There is an increasing focus on researching children admitted to hospital with new variants of CO... more There is an increasing focus on researching children admitted to hospital with new variants of COVID-19, combined with concerns with hyperinflammatory syndromes and the overuse of antimicrobials. Paediatric guidelines have been produced in Bangladesh to improve their care. Consequently, the objective is to document the management of children with COVID-19 among 24 hospitals in Bangladesh. Key outcome measures included the percentage prescribed different antimicrobials, adherence to paediatric guidelines and mortality rates using purposely developed report forms. The majority of 146 admitted children were aged 5 years or under (62.3%) and were boys (58.9%). Reasons for admission included fever, respiratory distress and coughing; 86.3% were prescribed antibiotics, typically parenterally, on the WHO ‘Watch’ list, and empirically (98.4%). There were no differences in antibiotic use whether hospitals followed paediatric guidance or not. There was no prescribing of antimalarials and limit...
Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by i... more Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by itchy, eczematous, sparsely tiny blisters that hold a clear watery substance. Additionally, the diseased skin can suppurate, occasionally with weeping with thickening of the affected skin. This is considered one of the top skin disorders involving both children and adult populations globally. The principal therapeutic intervention for AD is long-standing topical glucocorticoids, which have been used for several decades. Corticosteroid therapy brings several adverse drug effects (ADRs), including irreversible skin atrophy. Tacrolimus belongs to the class of calcineurin inhibitors, which is a type of immunomodulator possessing promising efficacy in treating AD. Topical tacrolimus is an effective and safe non-corticosteroid substitute treatment for AD. We reviewed the available literature to compare and institute the safety, efficacy, and effectiveness of tacrolimus when equated to corticosteroid therapy in managing AD.
Objective: At the start of the Covid-19 pandemic, educational establishments, including universit... more Objective: At the start of the Covid-19 pandemic, educational establishments, including universities, were closed. Educators in high-income countries quickly shifted all education online, building on available infrastructures and approaches. However, there were concerns in developing countries regarding the necessary skills among students and faculty as well as financial support for equipment and the internet. Consequently, a pilot was undertaken in Bangladesh to determine the impact of Covid-19 on the non-medical education system, building on similar research with healthcare professionals. Materials and Methods: A purposively designed questionnaire was disseminated among eight non-medical healthcare educators in private and public universities in Bangladesh. Results and Discussion: Private university educators reported their universities readily adopted e-learning systems and resumed classes more quickly than public universities. Both private and public university educators shared ...
Juvenile localized scleroderma (JLS) is a rare chronic inflammatory and fibrosing disorder. It ca... more Juvenile localized scleroderma (JLS) is a rare chronic inflammatory and fibrosing disorder. It can result in significant morbidity, disfigurement, and severe functional, aesthetic and psychological disabilities. Patients with JLS should be identified early, evaluated extensively, treated aggressively, and monitored carefully. Here the case of a 2 year old boy is reported who was admitted into the department of Paediatrics of Delta Medical College & Hospital, Dhaka, Bangladesh with painful swelling of all fingers of both hands for 6 months and blackish patches over the fingers for the last one and half months. Left little finger was the first finger affected and there was flexion contracture of both left little and index fingers. The boy was diagnosed as a case of juvenile localized scleroderma and was confirmed by skin biopsy. We treated the child with methotrexate and prednisolone. It is very essential to raise awareness about this disease among clinicians and also parents for earl...
Background & objective:The present study was undertaken to find the prevalence and pattern of chi... more Background & objective:The present study was undertaken to find the prevalence and pattern of childhood stroke and to see its clinical presentation and sub-types. Materials & Methods:The present cross sectional study was conducted in the Department of Pediatrics, BSMMU, Dhaka over a period of 6 months. A total of 30 children suffering from childhood stroke, provisionally diagnosed on the basis of clinical criteria and confirmed by neuroimaging were the study population.The demographic variables were age, sex, age at onset and age at case taking. The signs and symptoms at presentation, causes, investigations, neuro-imaging findings and final diagnosis were recorded. Result: Over half (53.4%) of the patients were in the range of 13 – 36 months with mean age of the patients being 39.1 ± 8.2 months. The mean age at onset was 36.2 ± 8.3 months. About 47% of patients were male and 53% female. Paresis of limb was invariably present, unconsciousness at onset (50%), convulsion (33.3%), aphas...
Objective: The focus on COVID-19 in children in low- and middle-income countries including Bangla... more Objective: The focus on COVID-19 in children in low- and middle-income countries including Bangladesh has been on addressing key issues including poor vaccination rates as well as mental health issues, domestic violence and child labour. However, the focus on optimally managing children in hospitals is changing with new variants and concerns with the development of hyperinflammatory syndromes. There are also concerns with the overuse of antimicrobials to treat patients with COVID-19 in hospitals enhancing resistance rates. The Bangladesh Paediatric Association have developed guidelines to improve patient care building on national guidance. Consequently, there is a need to document the current management of children with COVID-19 in Bangladesh and use the findings for future guidance. Methods: Rapid analysis of the management of children with COVID-19 among eight private and public hospitals in Bangladesh with varying numbers of in-patient beds using purposely developed case report f...
Background: Urinary tract infection (UTI) is common in children. About 7% girls and 2% of boys su... more Background: Urinary tract infection (UTI) is common in children. About 7% girls and 2% of boys suffer from symptomatic, culture positive UTI by 6 years of age. These children present with poor feeding, irritability, vomiting, fever, abdominal pain or failure to thrive. Now a days antibiotic resistance is a global problem which hampers appropriate treatment of urinary tract infection in children. This study was done to see clinical profile, common pathogens and their drug sensitivity pattern in UTI. Methodology: It is a prospective study conducted in Delta Medical College & Hospital, Dhaka. All cases collected from outdoor patient or inpatient who were clinically suspected as UTI were enrolled in this study from January 2015 to July 2017. Total 200 cases were included. History was taken properly. Diagnosis of UTI was confirmed by urinalysis and culture sensitivity (C/S). All informations were recorded in preformed data sheet. Results: Usual presentations of UTI were fever, abdominal ...
A 6 year old girl presented with not growing well, delayed milestone of development, feeding diff... more A 6 year old girl presented with not growing well, delayed milestone of development, feeding difficulty, constipation since birth and breathing difficulty for last 3 months. The diagnosis was congenital hypothyroidism which was confirmed by Serum FT4 & TSH. The patient was put on oral thyroxin and showed little improvement initially and discharged on request after 15 days but unfortunately she died after 1 month at her residence. DOI: http://dx.doi.org/10.3329/bmj.v41i1.18787 Bangladesh Medical Journal 2012 Vol. 41 No. 1; 59-61
Urinary tract infection (UTI) is one of the most common paediatric infections. By the time childr... more Urinary tract infection (UTI) is one of the most common paediatric infections. By the time children are 5 years old, about 8% of girls and about 1-2% of boys have had at least one episode of UTI. UTIs are caused mainly by colonic bacteria, such as Escherichia coli, followed by Klebsiella and Proteus. However, any organism that gains access to the urinary tract system may cause infection, including fungi (Candida species) and viruses. In some instances, UTI results in recognition of an important underlying structural abnormality of the urinary tract. The febrile infant or child with clinically significant bacteriuria and no other site of infection to explain the fever, even in the absence of systemic symptoms has UTI. Signs and symptoms of UTIs vary depending on the child's age and on which part of the urinary tract is infected. The diagnosis of UTI is based on routine microscopic examination and culture of a properly collected urine specimen. Imaging studies are done in selected...
Management of Atopic Dermatitis: The Role of Tacrolimus, 2022
Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by i... more Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by itchy, eczematous, sparsely tiny blisters that hold a clear watery substance. Additionally, the diseased skin can suppurate, occasionally with weeping with thickening of the affected skin. This is considered one of the top skin disorders involving both children and adult populations globally. The principal therapeutic intervention for AD is long-standing topical glucocorticoids, which have been used for several decades. Corticosteroid therapy brings several adverse drug effects (ADRs), including irreversible skin atrophy. Tacrolimus belongs to the class of calcineurin inhibitors, which is a type of immunomodulator possessing promising efficacy in treating AD. Topical tacrolimus is an effective and safe non-corticosteroid substitute treatment for AD. We reviewed the available literature to compare and institute the safety, efficacy, and effectiveness of tacrolimus when equated to corticosteroid therapy in managing AD.
There is an increasing focus on researching children admitted to hospital with new variants of CO... more There is an increasing focus on researching children admitted to hospital with new variants of COVID-19, combined with concerns with hyperinflammatory syndromes and the overuse of antimicrobials. Paediatric guidelines have been produced in Bangladesh to improve their care. Consequently, the objective is to document the management of children with COVID-19 among 24 hospitals in Bangladesh. Key outcome measures included the percentage prescribed different antimicrobials, adherence to paediatric guidelines and mortality rates using purposely developed report forms. The majority of 146 admitted children were aged 5 years or under (62.3%) and were boys (58.9%). Reasons for admission included fever, respiratory distress and coughing; 86.3% were prescribed antibiotics, typically parenterally, on the WHO ‘Watch’ list, and empirically (98.4%). There were no differences in antibiotic use whether hospitals followed paediatric guidance or not. There was no prescribing of antimalarials and limit...
Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by i... more Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by itchy, eczematous, sparsely tiny blisters that hold a clear watery substance. Additionally, the diseased skin can suppurate, occasionally with weeping with thickening of the affected skin. This is considered one of the top skin disorders involving both children and adult populations globally. The principal therapeutic intervention for AD is long-standing topical glucocorticoids, which have been used for several decades. Corticosteroid therapy brings several adverse drug effects (ADRs), including irreversible skin atrophy. Tacrolimus belongs to the class of calcineurin inhibitors, which is a type of immunomodulator possessing promising efficacy in treating AD. Topical tacrolimus is an effective and safe non-corticosteroid substitute treatment for AD. We reviewed the available literature to compare and institute the safety, efficacy, and effectiveness of tacrolimus when equated to corticosteroid therapy in managing AD.
Objective: At the start of the Covid-19 pandemic, educational establishments, including universit... more Objective: At the start of the Covid-19 pandemic, educational establishments, including universities, were closed. Educators in high-income countries quickly shifted all education online, building on available infrastructures and approaches. However, there were concerns in developing countries regarding the necessary skills among students and faculty as well as financial support for equipment and the internet. Consequently, a pilot was undertaken in Bangladesh to determine the impact of Covid-19 on the non-medical education system, building on similar research with healthcare professionals. Materials and Methods: A purposively designed questionnaire was disseminated among eight non-medical healthcare educators in private and public universities in Bangladesh. Results and Discussion: Private university educators reported their universities readily adopted e-learning systems and resumed classes more quickly than public universities. Both private and public university educators shared ...
Juvenile localized scleroderma (JLS) is a rare chronic inflammatory and fibrosing disorder. It ca... more Juvenile localized scleroderma (JLS) is a rare chronic inflammatory and fibrosing disorder. It can result in significant morbidity, disfigurement, and severe functional, aesthetic and psychological disabilities. Patients with JLS should be identified early, evaluated extensively, treated aggressively, and monitored carefully. Here the case of a 2 year old boy is reported who was admitted into the department of Paediatrics of Delta Medical College & Hospital, Dhaka, Bangladesh with painful swelling of all fingers of both hands for 6 months and blackish patches over the fingers for the last one and half months. Left little finger was the first finger affected and there was flexion contracture of both left little and index fingers. The boy was diagnosed as a case of juvenile localized scleroderma and was confirmed by skin biopsy. We treated the child with methotrexate and prednisolone. It is very essential to raise awareness about this disease among clinicians and also parents for earl...
Background & objective:The present study was undertaken to find the prevalence and pattern of chi... more Background & objective:The present study was undertaken to find the prevalence and pattern of childhood stroke and to see its clinical presentation and sub-types. Materials & Methods:The present cross sectional study was conducted in the Department of Pediatrics, BSMMU, Dhaka over a period of 6 months. A total of 30 children suffering from childhood stroke, provisionally diagnosed on the basis of clinical criteria and confirmed by neuroimaging were the study population.The demographic variables were age, sex, age at onset and age at case taking. The signs and symptoms at presentation, causes, investigations, neuro-imaging findings and final diagnosis were recorded. Result: Over half (53.4%) of the patients were in the range of 13 – 36 months with mean age of the patients being 39.1 ± 8.2 months. The mean age at onset was 36.2 ± 8.3 months. About 47% of patients were male and 53% female. Paresis of limb was invariably present, unconsciousness at onset (50%), convulsion (33.3%), aphas...
Objective: The focus on COVID-19 in children in low- and middle-income countries including Bangla... more Objective: The focus on COVID-19 in children in low- and middle-income countries including Bangladesh has been on addressing key issues including poor vaccination rates as well as mental health issues, domestic violence and child labour. However, the focus on optimally managing children in hospitals is changing with new variants and concerns with the development of hyperinflammatory syndromes. There are also concerns with the overuse of antimicrobials to treat patients with COVID-19 in hospitals enhancing resistance rates. The Bangladesh Paediatric Association have developed guidelines to improve patient care building on national guidance. Consequently, there is a need to document the current management of children with COVID-19 in Bangladesh and use the findings for future guidance. Methods: Rapid analysis of the management of children with COVID-19 among eight private and public hospitals in Bangladesh with varying numbers of in-patient beds using purposely developed case report f...
Background: Urinary tract infection (UTI) is common in children. About 7% girls and 2% of boys su... more Background: Urinary tract infection (UTI) is common in children. About 7% girls and 2% of boys suffer from symptomatic, culture positive UTI by 6 years of age. These children present with poor feeding, irritability, vomiting, fever, abdominal pain or failure to thrive. Now a days antibiotic resistance is a global problem which hampers appropriate treatment of urinary tract infection in children. This study was done to see clinical profile, common pathogens and their drug sensitivity pattern in UTI. Methodology: It is a prospective study conducted in Delta Medical College & Hospital, Dhaka. All cases collected from outdoor patient or inpatient who were clinically suspected as UTI were enrolled in this study from January 2015 to July 2017. Total 200 cases were included. History was taken properly. Diagnosis of UTI was confirmed by urinalysis and culture sensitivity (C/S). All informations were recorded in preformed data sheet. Results: Usual presentations of UTI were fever, abdominal ...
A 6 year old girl presented with not growing well, delayed milestone of development, feeding diff... more A 6 year old girl presented with not growing well, delayed milestone of development, feeding difficulty, constipation since birth and breathing difficulty for last 3 months. The diagnosis was congenital hypothyroidism which was confirmed by Serum FT4 & TSH. The patient was put on oral thyroxin and showed little improvement initially and discharged on request after 15 days but unfortunately she died after 1 month at her residence. DOI: http://dx.doi.org/10.3329/bmj.v41i1.18787 Bangladesh Medical Journal 2012 Vol. 41 No. 1; 59-61
Urinary tract infection (UTI) is one of the most common paediatric infections. By the time childr... more Urinary tract infection (UTI) is one of the most common paediatric infections. By the time children are 5 years old, about 8% of girls and about 1-2% of boys have had at least one episode of UTI. UTIs are caused mainly by colonic bacteria, such as Escherichia coli, followed by Klebsiella and Proteus. However, any organism that gains access to the urinary tract system may cause infection, including fungi (Candida species) and viruses. In some instances, UTI results in recognition of an important underlying structural abnormality of the urinary tract. The febrile infant or child with clinically significant bacteriuria and no other site of infection to explain the fever, even in the absence of systemic symptoms has UTI. Signs and symptoms of UTIs vary depending on the child's age and on which part of the urinary tract is infected. The diagnosis of UTI is based on routine microscopic examination and culture of a properly collected urine specimen. Imaging studies are done in selected...
Management of Atopic Dermatitis: The Role of Tacrolimus, 2022
Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by i... more Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by itchy, eczematous, sparsely tiny blisters that hold a clear watery substance. Additionally, the diseased skin can suppurate, occasionally with weeping with thickening of the affected skin. This is considered one of the top skin disorders involving both children and adult populations globally. The principal therapeutic intervention for AD is long-standing topical glucocorticoids, which have been used for several decades. Corticosteroid therapy brings several adverse drug effects (ADRs), including irreversible skin atrophy. Tacrolimus belongs to the class of calcineurin inhibitors, which is a type of immunomodulator possessing promising efficacy in treating AD. Topical tacrolimus is an effective and safe non-corticosteroid substitute treatment for AD. We reviewed the available literature to compare and institute the safety, efficacy, and effectiveness of tacrolimus when equated to corticosteroid therapy in managing AD.
Uploads
Papers by Nadia Nusrat