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    Natasha Santana-Vaz

    Introduction: Adenocarcinoma represents less than 2% of all bladder carcinomas. Metastatic adenocarcinoma is the most common form and usually represents a direct extension from a primary lesion either in the colon, prostate or the female... more
    Introduction: Adenocarcinoma represents less than 2% of all bladder carcinomas. Metastatic adenocarcinoma is the most common form and usually represents a direct extension from a primary lesion either in the colon, prostate or the female genital organs. Other categories include primary vesical or urachal. Case Report: We present a case of 79 year old female presented with microscopic hematuria, frequency, urgency, and weight loss. An adenocarcinoma of the urinary bladder of intestinal origin was founded. Conclusion: Primary adenocarcinoma of urinary bladder is an uncommon neoplasm and the reported incidence of the primary adenocarcinoma is 0.5–2%. It represents a diagnostic challenge raising the inquiry about the site of the lesion. Three major classes were identified: primary vesical adenocarcinoma, urachal adenocarcinoma, and extravesical adenocarcinoma involving the bladder. The metastatic adenocarcinoma is the most common category representing a direct extension from a nearby or...
    Motor neurone disease (MND) is a chronic, progressive and currently incurable neurodegenerative disorder. This case report discusses an instance of MND presenting initially as polycythaemia, caused via insidious respiratory failure... more
    Motor neurone disease (MND) is a chronic, progressive and currently incurable neurodegenerative disorder. This case report discusses an instance of MND presenting initially as polycythaemia, caused via insidious respiratory failure through ventilatory insufficiency. This case aims to improve clinicians' awareness of this atypical presentation and highlights the need for a high index of suspicion of respiratory failure in any patient with polycythaemia. Finally it demonstrates an improvement in quality of life associated with the use of non-invasive ventilation (NIV) in a patient with MND.