WOS: 000290235800004Aim. The current study aims to investigate the early out comes of the new tec... more WOS: 000290235800004Aim. The current study aims to investigate the early out comes of the new technique applied to degenerative spinal disc disease (DSDD) patients. For this purpose 25 patients having DSDD, spinal stenosis and spondilolisthesis were included in the study. The treatments were performed on a two-stage procedure, first surgically with laminectomy, discectomy (when needed) and then the low invasive non-fusion dynamic stabilization with InterS. Methods. The outcomes of the procedure has been followed up for 12 months. Patients were followed up by means of clinical and radiographic techniques. All of the three group of patients underwent a midline decompressive laminectomy with foraminotomies at the effected levels. Furthermore, in lumbar disc hernia cases, discectomy was performed. Oswestry pain scale was used for the clinical evaluation. Results. The study included patients from both sexes (16 females, 9 males) with a mean age of 54.45 years (range 37-68). Symptoms and signs included pain (100), 15 patients have DDD, 7 patients have spinal stenosis, 3 patients spondylolisthesis. Localization was as follows: L3-4: 5 (20%), L4-5: 20 (80%). Satisfactory results were demonstrated in 21 (84%) patients. The average of Oswestry scores was 42.15 in the preoperative period and 8.8 in the postoperative period. Conclusion. Non-fusion dynamic stabilization method of InterS type is a safe procedure. We believe this technique may reduce higher complication rates for patients with spinal stenosis and spondylolysthesis, degenerative disc disease. Motion preservation, early mobilization, short hospital stays and shorter recovery are the main advantages of the operation
ATILLA, PERGIN/0000-0001-5132-0002WOS: 000347120800005Background: The aim of this study was to ex... more ATILLA, PERGIN/0000-0001-5132-0002WOS: 000347120800005Background: The aim of this study was to explore the effects of glutamine in brain ischemia/reperfusion model in rat. Methods: Right common carotid arteries of 24 Wistar albino rats were clamped for a duration of 30 minutes. Two hours later, except CONTROL group, glutamine was infused into left femoral vein of rats in GLIV group; and glutamine and normal saline was administered into cisterna magna of rats in GLIS and SFIS groups, respectively. After 7 days, all animals were decapitated and each brain was divided into two hemispheres for histopathological and biochemical evaluation. The right hemisphere was called "Hypoxia/Reperfusion side (HRS)" and the left hemisphere was called " Toxicity side (TS)". Results: In TS and HRS, degenerated neuron counts of GLIV groups were significantly higher than other groups' values. Degenerated neuron count values of TS were significantly lower than HRS values for GLIS, and SFIS groups, but the results of GLIV group in TS did not different from the GLIV group in HRS. LPO levels of TS and HRS of the groups was not statistically significant. Conclusion: This study results showed that glutamine had no beneficial effect to the hypoxia/reperfusion injury in rat model
Over a 3-year period in our clinic, surgeons operated on 32 persons over 65 years old with lumbar... more Over a 3-year period in our clinic, surgeons operated on 32 persons over 65 years old with lumbar spinal stenosis. This article presents the retrospective analysis of the clinical, radiological, and short-term surgical outcomes. The stenosis seen most commonly among the elderly develops focally at the intervertebral junctions as a result of a complex process of disc degeneration, facet arthropathy, ligamentum flavum hypertrophy, spondylosis, and sometimes spondylolisthesis. All patients underwent a midline decompressive laminectomy with foraminotomies at the affected levels, and discectomy was performed in persons with lumbar disc hernia. Average age was 71.15 +/- 5.09 (65-80); 50% (16) were women, and 50% (16) were men. The most frequent symptoms were pain (96.9%) and neurological claudication (90.6%). The average preoperative duration of the symptoms was 139.87 +/- 115.03 weeks. The most frequent neurological symptoms were reflex disturbances (62.5%), Lasèques's sign (SLR) (+)(53%), and motor deficit (50%). The anteroposterior diameter of the spinal canal was less than 11.5 mm in 71.9% of the cases. In 62.5% of the patients, partial recovery was observed in the short term; 68.8% of the patients underwent laminectomy. Of those, 87.5% had total and 12.5% had partial laminectomies. In addition to laminectomy, discectomy was performed in 31.3% of the patients. Total laminectomy was more likely to be performed on patients older than 65 years, because the anteroposterior diameter was more likely to be below 11.5 mm in this cohort of patients. In lumbar stenosis, surgical treatment-decompression-is an effective method. Surgery has been demonstrated to be effective even in patients over the age of 75 years.
WOS: 000290235800004Aim. The current study aims to investigate the early out comes of the new tec... more WOS: 000290235800004Aim. The current study aims to investigate the early out comes of the new technique applied to degenerative spinal disc disease (DSDD) patients. For this purpose 25 patients having DSDD, spinal stenosis and spondilolisthesis were included in the study. The treatments were performed on a two-stage procedure, first surgically with laminectomy, discectomy (when needed) and then the low invasive non-fusion dynamic stabilization with InterS. Methods. The outcomes of the procedure has been followed up for 12 months. Patients were followed up by means of clinical and radiographic techniques. All of the three group of patients underwent a midline decompressive laminectomy with foraminotomies at the effected levels. Furthermore, in lumbar disc hernia cases, discectomy was performed. Oswestry pain scale was used for the clinical evaluation. Results. The study included patients from both sexes (16 females, 9 males) with a mean age of 54.45 years (range 37-68). Symptoms and signs included pain (100), 15 patients have DDD, 7 patients have spinal stenosis, 3 patients spondylolisthesis. Localization was as follows: L3-4: 5 (20%), L4-5: 20 (80%). Satisfactory results were demonstrated in 21 (84%) patients. The average of Oswestry scores was 42.15 in the preoperative period and 8.8 in the postoperative period. Conclusion. Non-fusion dynamic stabilization method of InterS type is a safe procedure. We believe this technique may reduce higher complication rates for patients with spinal stenosis and spondylolysthesis, degenerative disc disease. Motion preservation, early mobilization, short hospital stays and shorter recovery are the main advantages of the operation
ATILLA, PERGIN/0000-0001-5132-0002WOS: 000347120800005Background: The aim of this study was to ex... more ATILLA, PERGIN/0000-0001-5132-0002WOS: 000347120800005Background: The aim of this study was to explore the effects of glutamine in brain ischemia/reperfusion model in rat. Methods: Right common carotid arteries of 24 Wistar albino rats were clamped for a duration of 30 minutes. Two hours later, except CONTROL group, glutamine was infused into left femoral vein of rats in GLIV group; and glutamine and normal saline was administered into cisterna magna of rats in GLIS and SFIS groups, respectively. After 7 days, all animals were decapitated and each brain was divided into two hemispheres for histopathological and biochemical evaluation. The right hemisphere was called "Hypoxia/Reperfusion side (HRS)" and the left hemisphere was called " Toxicity side (TS)". Results: In TS and HRS, degenerated neuron counts of GLIV groups were significantly higher than other groups' values. Degenerated neuron count values of TS were significantly lower than HRS values for GLIS, and SFIS groups, but the results of GLIV group in TS did not different from the GLIV group in HRS. LPO levels of TS and HRS of the groups was not statistically significant. Conclusion: This study results showed that glutamine had no beneficial effect to the hypoxia/reperfusion injury in rat model
Over a 3-year period in our clinic, surgeons operated on 32 persons over 65 years old with lumbar... more Over a 3-year period in our clinic, surgeons operated on 32 persons over 65 years old with lumbar spinal stenosis. This article presents the retrospective analysis of the clinical, radiological, and short-term surgical outcomes. The stenosis seen most commonly among the elderly develops focally at the intervertebral junctions as a result of a complex process of disc degeneration, facet arthropathy, ligamentum flavum hypertrophy, spondylosis, and sometimes spondylolisthesis. All patients underwent a midline decompressive laminectomy with foraminotomies at the affected levels, and discectomy was performed in persons with lumbar disc hernia. Average age was 71.15 +/- 5.09 (65-80); 50% (16) were women, and 50% (16) were men. The most frequent symptoms were pain (96.9%) and neurological claudication (90.6%). The average preoperative duration of the symptoms was 139.87 +/- 115.03 weeks. The most frequent neurological symptoms were reflex disturbances (62.5%), Lasèques's sign (SLR) (+)(53%), and motor deficit (50%). The anteroposterior diameter of the spinal canal was less than 11.5 mm in 71.9% of the cases. In 62.5% of the patients, partial recovery was observed in the short term; 68.8% of the patients underwent laminectomy. Of those, 87.5% had total and 12.5% had partial laminectomies. In addition to laminectomy, discectomy was performed in 31.3% of the patients. Total laminectomy was more likely to be performed on patients older than 65 years, because the anteroposterior diameter was more likely to be below 11.5 mm in this cohort of patients. In lumbar stenosis, surgical treatment-decompression-is an effective method. Surgery has been demonstrated to be effective even in patients over the age of 75 years.
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