Necrotizing fasciitis is a grave complication of ascending omphalitis in the neonate, but because... more Necrotizing fasciitis is a grave complication of ascending omphalitis in the neonate, but because it is rare some of the signs are not well documented. Rapidly progressive anterior abdominal wall edema and cellulitis were noted in 16 patients who were clinically diagnosed with necrotizing fasciitis. Fifteen of these patients died soon after emergence of anterior abdominal wall edema and cellulitis. The appearance of anterior abdominal edema and cellulitis in a patient with ascending omphalitis has serious implications and demands intensive care if the patient is to survive.
Early recognition of neonatal hyperbilirubinemia is essential for prevention of bilirubin neuroto... more Early recognition of neonatal hyperbilirubinemia is essential for prevention of bilirubin neurotoxicity and its long-term sequelae. High rates of home delivery in low- and middle-income countries (LMICs) as well as early discharge post-delivery (within 24hours) make community surveillance for neonatal hyperbilirubinemia highly important. Here, we performed a literature review to estimate the level of societal awareness of neonatal hyperbilirubinemia. We searched several databases for studies assessing the knowledge and awareness of neonatal hyperbilirubinemia. We retrieved 211 citations from 206 databases with five being in the grey literature. 52 selected articles were further reviewed. Data from these studies were then analyzed using Stata software (Statacorp® LLC Texas USA). We found that the pooled estimate of societal awareness of neonatal hyperbilirubinemia was 67% (95% confidence interval [CI]: 60, 74). There however was a publication bias (Begg test: P ≤ 0.01; Egger P = 0.06...
Introduction: In Nigeria, chronic kidney disease (CKD) incidence in children ranges between 2-6 c... more Introduction: In Nigeria, chronic kidney disease (CKD) incidence in children ranges between 2-6 cases per annum. Management of CKD which includes dialysis and renal transplant (renal replacement therapy) is not easily obtainable and affordable in our environment. Identifying patients with increased risk and prompt treatment aimed at risk reduction, slow down the progression. Consequently, screening for early detection therefore becomes inevitable, even individuals who appear normal should be screened for modifiable CKD risk factors such as proteinuria, hypertension and obesity. Objectives: To screen for risk factors for CKD in children attending paediatric outpatient clinic in Federal Medical Center Asaba. Patients and Methods: It was a cross-sectional descriptive study in which all the children 3-16 years, attending the children outpatient clinic, and have satisfied the inclusion criteria were screened for proteinuria, hypertension and obesit...
AIM Over two thirds of newborn deaths occur in Africa and South Asia and respiratory failure is a... more AIM Over two thirds of newborn deaths occur in Africa and South Asia and respiratory failure is a major contributor of these deaths. The exact availability of continuous positive airway pressure (CPAP) and surfactant in Africa is unknown. The aim of this study was to describe the availability of newborn respiratory care treatments in the countries of Africa. METHODS Surveys, in English, French and Portuguese were sent to neonatal leaders in all 48 continental countries and the two islands with populations over 1 million. RESULTS Forty-nine (98%) countries responded. Twenty-one countries reported less than 50 paediatricians and 12 countries had no neonatologists. Speciality neonatal nursing was recognised in 57% of countries. Most units were able to provide supplemental oxygen. CPAP was available in 63% and 67% of the most well-equipped government and private hospitals. Surfactant was available in 33% and 39% of the most well-equipped public and private hospital respectively. Availab...
BackgroundQuality health care service delivery to children and adolescents is enhanced by continu... more BackgroundQuality health care service delivery to children and adolescents is enhanced by continuous research into the health challenges of this subpopulation led by paediatricians with tremendous capacity to investigate and proffer solutions to the myriads of childhood illnesses. Understanding the health issues therefore is the foundation for implementation of viable interventions that assure optimum service delivery. In view of this background, the Paediatric Association of Nigeria (PAN) directed that research into children’s health challenges in Nigeria should be brought to the front burner in the country. Pursuant to this laudable goal this study was conceived to evaluate the research capacity and capability of paediatricians in Nigeria and the institutions they represent. In view of above needs, this study aimed at evaluating the research capacities and challenges among paediatricians.MethodsThe survey used a cross-sectional nationwide design to enroll paediatricians into the s...
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, Jan 25, 2018
Surfactant replacement therapy (SRT) is the standard of care in developed countries. Poor access ... more Surfactant replacement therapy (SRT) is the standard of care in developed countries. Poor access to surfactant limits its use in low resource settings. The extent of its use and the effect of its regular use on the preterm in such settings is unknown. This study assessed the extent of exogenous surfactant utilization in Nigerian tertiary care facilities and the benefits of its regular use to the preterm population. A two-phase cross-sectional study design evaluated the response from a respondent administered structured questionnaire addressed to health care providers from 54 centers and a targeted assessment of the outcome of the regular use of exogenous surfactant in a tertiary care facility from January 2014 to December 2016. SRT was available in 16.7% of 54 units evaluated nationally; three (33.3%) were located in south-south and south-west respectively, 2 (22.2%) in southeast and one (11.1%) in north-central regions of the country. Twenty-two percent of the units were private ce...
Sickle cell disease affects about 150,000 births annually in Nigeria. Early diagnosis is hampered... more Sickle cell disease affects about 150,000 births annually in Nigeria. Early diagnosis is hampered by factors such as centralized and urban localization of laboratories, high cost of diagnostic equipment and inadequate skilled manpower to operate them. The need for a low-cost, portable, easy-to-use diagnostic test for sickle cell disease is critical, especially in resource-poor countries. In this study, we evaluated the performance characteristics of a novel point-of-care testing device (SickleSCAN™), and its acceptability and feasibility, as a possible screening tool for sickle cell disease. In the first phase, we assessed the performance characteristics of SickleSCAN™ by evaluating 57 subjects comprising both children and adults attending a primary health center, for Hb SS (β(S)/β(S); HBB: c.20A>T), Hb SC (β(S)/β(C); HBB: c.19G>A) and Hb AS (β(A)/β(S)) using SickleSCAN™, cellulose acetate electrophoresis (CAE) and high performance liquid chromatography (HPLC). Performance cha...
Necrotizing fasciitis is a grave complication of ascending omphalitis in the neonate, but because... more Necrotizing fasciitis is a grave complication of ascending omphalitis in the neonate, but because it is rare some of the signs are not well documented. Rapidly progressive anterior abdominal wall edema and cellulitis were noted in 16 patients who were clinically diagnosed with necrotizing fasciitis. Fifteen of these patients died soon after emergence of anterior abdominal wall edema and cellulitis. The appearance of anterior abdominal edema and cellulitis in a patient with ascending omphalitis has serious implications and demands intensive care if the patient is to survive.
Early recognition of neonatal hyperbilirubinemia is essential for prevention of bilirubin neuroto... more Early recognition of neonatal hyperbilirubinemia is essential for prevention of bilirubin neurotoxicity and its long-term sequelae. High rates of home delivery in low- and middle-income countries (LMICs) as well as early discharge post-delivery (within 24hours) make community surveillance for neonatal hyperbilirubinemia highly important. Here, we performed a literature review to estimate the level of societal awareness of neonatal hyperbilirubinemia. We searched several databases for studies assessing the knowledge and awareness of neonatal hyperbilirubinemia. We retrieved 211 citations from 206 databases with five being in the grey literature. 52 selected articles were further reviewed. Data from these studies were then analyzed using Stata software (Statacorp® LLC Texas USA). We found that the pooled estimate of societal awareness of neonatal hyperbilirubinemia was 67% (95% confidence interval [CI]: 60, 74). There however was a publication bias (Begg test: P ≤ 0.01; Egger P = 0.06...
Introduction: In Nigeria, chronic kidney disease (CKD) incidence in children ranges between 2-6 c... more Introduction: In Nigeria, chronic kidney disease (CKD) incidence in children ranges between 2-6 cases per annum. Management of CKD which includes dialysis and renal transplant (renal replacement therapy) is not easily obtainable and affordable in our environment. Identifying patients with increased risk and prompt treatment aimed at risk reduction, slow down the progression. Consequently, screening for early detection therefore becomes inevitable, even individuals who appear normal should be screened for modifiable CKD risk factors such as proteinuria, hypertension and obesity. Objectives: To screen for risk factors for CKD in children attending paediatric outpatient clinic in Federal Medical Center Asaba. Patients and Methods: It was a cross-sectional descriptive study in which all the children 3-16 years, attending the children outpatient clinic, and have satisfied the inclusion criteria were screened for proteinuria, hypertension and obesit...
AIM Over two thirds of newborn deaths occur in Africa and South Asia and respiratory failure is a... more AIM Over two thirds of newborn deaths occur in Africa and South Asia and respiratory failure is a major contributor of these deaths. The exact availability of continuous positive airway pressure (CPAP) and surfactant in Africa is unknown. The aim of this study was to describe the availability of newborn respiratory care treatments in the countries of Africa. METHODS Surveys, in English, French and Portuguese were sent to neonatal leaders in all 48 continental countries and the two islands with populations over 1 million. RESULTS Forty-nine (98%) countries responded. Twenty-one countries reported less than 50 paediatricians and 12 countries had no neonatologists. Speciality neonatal nursing was recognised in 57% of countries. Most units were able to provide supplemental oxygen. CPAP was available in 63% and 67% of the most well-equipped government and private hospitals. Surfactant was available in 33% and 39% of the most well-equipped public and private hospital respectively. Availab...
BackgroundQuality health care service delivery to children and adolescents is enhanced by continu... more BackgroundQuality health care service delivery to children and adolescents is enhanced by continuous research into the health challenges of this subpopulation led by paediatricians with tremendous capacity to investigate and proffer solutions to the myriads of childhood illnesses. Understanding the health issues therefore is the foundation for implementation of viable interventions that assure optimum service delivery. In view of this background, the Paediatric Association of Nigeria (PAN) directed that research into children’s health challenges in Nigeria should be brought to the front burner in the country. Pursuant to this laudable goal this study was conceived to evaluate the research capacity and capability of paediatricians in Nigeria and the institutions they represent. In view of above needs, this study aimed at evaluating the research capacities and challenges among paediatricians.MethodsThe survey used a cross-sectional nationwide design to enroll paediatricians into the s...
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, Jan 25, 2018
Surfactant replacement therapy (SRT) is the standard of care in developed countries. Poor access ... more Surfactant replacement therapy (SRT) is the standard of care in developed countries. Poor access to surfactant limits its use in low resource settings. The extent of its use and the effect of its regular use on the preterm in such settings is unknown. This study assessed the extent of exogenous surfactant utilization in Nigerian tertiary care facilities and the benefits of its regular use to the preterm population. A two-phase cross-sectional study design evaluated the response from a respondent administered structured questionnaire addressed to health care providers from 54 centers and a targeted assessment of the outcome of the regular use of exogenous surfactant in a tertiary care facility from January 2014 to December 2016. SRT was available in 16.7% of 54 units evaluated nationally; three (33.3%) were located in south-south and south-west respectively, 2 (22.2%) in southeast and one (11.1%) in north-central regions of the country. Twenty-two percent of the units were private ce...
Sickle cell disease affects about 150,000 births annually in Nigeria. Early diagnosis is hampered... more Sickle cell disease affects about 150,000 births annually in Nigeria. Early diagnosis is hampered by factors such as centralized and urban localization of laboratories, high cost of diagnostic equipment and inadequate skilled manpower to operate them. The need for a low-cost, portable, easy-to-use diagnostic test for sickle cell disease is critical, especially in resource-poor countries. In this study, we evaluated the performance characteristics of a novel point-of-care testing device (SickleSCAN™), and its acceptability and feasibility, as a possible screening tool for sickle cell disease. In the first phase, we assessed the performance characteristics of SickleSCAN™ by evaluating 57 subjects comprising both children and adults attending a primary health center, for Hb SS (β(S)/β(S); HBB: c.20A>T), Hb SC (β(S)/β(C); HBB: c.19G>A) and Hb AS (β(A)/β(S)) using SickleSCAN™, cellulose acetate electrophoresis (CAE) and high performance liquid chromatography (HPLC). Performance cha...
The voices of children and young people during COVID‐19: A critical review of methods, 2022
This is the pre-peer reviewed version of the following article: Jörgensen E, Koller D, Raman S, O... more This is the pre-peer reviewed version of the following article: Jörgensen E, Koller D, Raman S, Olatunya O, Asemota O, Ekpenyong BN, Gunnlaugsson G, Okolo A “The voices of children and young people during COVID-19: A critical review of methods”. Acta Paediatr. 2022;00:1–12. which has been published in final form at https://doi.org/10.1111/apa.16422. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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