Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, Jan 9, 2009
Şakir Arslan, M. Emin Kalkan, Yekta Gürlertop Cardiology Department, Faculty of Medicine, Ataturk... more Şakir Arslan, M. Emin Kalkan, Yekta Gürlertop Cardiology Department, Faculty of Medicine, Ataturk University, Erzurum, Turkey ... Cem Köz, İnanç Güvenç*, Oben Baysan, Mehmet Yokuşoğlu, Haldun Karagöz1, Ömür Ataoğlu2 From Departments of Cardiology and *Radiology ...
We report a case of large renal hemangioma that completely filled the collecting system in a 43-y... more We report a case of large renal hemangioma that completely filled the collecting system in a 43-year-old man. Most of the renal hemangiomas are small in size and this situation is extremely rare. The diagnosis and treatment of the case is discussed.
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2003
In a rabbit model of squamous cell carcinoma of the tongue, we monitored histopathologic changes ... more In a rabbit model of squamous cell carcinoma of the tongue, we monitored histopathologic changes and assessed the effect of selenium against carcinogenesis. The study included 36 male albino New Zealand rabbits. To induce squamous cell carcinoma of the tongue, 9,10-dimethyl-1,2-benzanthracene (DMBA)-acetone solution was applied three times a week for a duration of 20 weeks under anesthesia with xylazine hydrochloride and ketamine. The rabbits were randomly assigned to receive either pure tap water (24 rabbits) or tap water supplemented with 4 ppm sodium selenite (12 rabbits). One rabbit in each group was sacrificed at the end of 4, 8, 12 and 16 weeks, and the remaining rabbits at the end of 20 weeks for macroscopic and microscopic examination of the tongue. By week 20, two rabbits in the selenium group, and nine rabbits receiving tap water died from acute necrotizing bronchopneumonia due to pasteurellosis. Dysplasia was significantly less in selenium-receiving rabbits (16.7% vs 66.7...
Osteoblastoma is a rare primary bone tumor that is curable by complete excision. There are few da... more Osteoblastoma is a rare primary bone tumor that is curable by complete excision. There are few data about the effectiveness of chemotherapy or radiotherapy in the treatment of recurrent osteoblastoma. We report a 13-year-old girl wit recurrent osteoblastoma who, after in complete surgical excision, responded to treatment with radiotherapy and later with chemotherapy. Surgery remains the treatment of choice for osteoblastoma. Radiotherapy and chemotherapy either alone or together may be useful in selected patients with recurrent, aggressive tumor or in patients with surgically unresectable disease.
Forty-four pathologic specimens of 39 bladder cancer patients were analyzed immunohistochemically... more Forty-four pathologic specimens of 39 bladder cancer patients were analyzed immunohistochemically with D07 monoclonal antibody to detect over-expression of mutant p53 gene. The findings were interpreted by correlating with patient age, sex, cigarette smoking, number and macroscopic appearance of tumour, histological tumour grade, muscular invasion, vascular invasion, necrosis and urothelial atypia or dysplasia. Mutant p53 gene was over-expressed in 8 (18.2%) specimens. Statistically significant correlation with grade, vascular invasion, necrosis and patient sex was found with p53 over-expression. Available follow-up data were insufficient to draw a conclusion about the prognostic role of p53 over-expression. Prospective studies with larger number of patients are needed to define the exact place of nuclear p53 over-expression in transitional cell bladder cancer.
It is difficult to recognize epithelioid trophoblastic tumor (ETT) as a trophoblastic disease bec... more It is difficult to recognize epithelioid trophoblastic tumor (ETT) as a trophoblastic disease because of its rarity and growth pattern simulating a carcinoma. A 36-year-old woman with stage IB(1) squamous cell carcinoma of the uterine cervix and a high serum beta-human chorionic gonadotropin (beta-hCG) level underwent radical hysterectomy with pelvic and para-aortic lymphadenectomy. However, light microscopic findings and immunohistochemical studies with pan-cytokeratin, epithelial membrane antigen, inhibin-alpha, beta-hCG, and human placental lactogen revealed ETT of the endocervix. The patient is alive with no evidence of disease 12 months after surgery. Before the patient is resorted to radical surgical interventions for assumed cervical carcinoma, ETT should be ruled out in women of reproductive age with endocervical tumors and elevated serum beta-hCG levels.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, Jan 9, 2009
Şakir Arslan, M. Emin Kalkan, Yekta Gürlertop Cardiology Department, Faculty of Medicine, Ataturk... more Şakir Arslan, M. Emin Kalkan, Yekta Gürlertop Cardiology Department, Faculty of Medicine, Ataturk University, Erzurum, Turkey ... Cem Köz, İnanç Güvenç*, Oben Baysan, Mehmet Yokuşoğlu, Haldun Karagöz1, Ömür Ataoğlu2 From Departments of Cardiology and *Radiology ...
We report a case of large renal hemangioma that completely filled the collecting system in a 43-y... more We report a case of large renal hemangioma that completely filled the collecting system in a 43-year-old man. Most of the renal hemangiomas are small in size and this situation is extremely rare. The diagnosis and treatment of the case is discussed.
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2003
In a rabbit model of squamous cell carcinoma of the tongue, we monitored histopathologic changes ... more In a rabbit model of squamous cell carcinoma of the tongue, we monitored histopathologic changes and assessed the effect of selenium against carcinogenesis. The study included 36 male albino New Zealand rabbits. To induce squamous cell carcinoma of the tongue, 9,10-dimethyl-1,2-benzanthracene (DMBA)-acetone solution was applied three times a week for a duration of 20 weeks under anesthesia with xylazine hydrochloride and ketamine. The rabbits were randomly assigned to receive either pure tap water (24 rabbits) or tap water supplemented with 4 ppm sodium selenite (12 rabbits). One rabbit in each group was sacrificed at the end of 4, 8, 12 and 16 weeks, and the remaining rabbits at the end of 20 weeks for macroscopic and microscopic examination of the tongue. By week 20, two rabbits in the selenium group, and nine rabbits receiving tap water died from acute necrotizing bronchopneumonia due to pasteurellosis. Dysplasia was significantly less in selenium-receiving rabbits (16.7% vs 66.7...
Osteoblastoma is a rare primary bone tumor that is curable by complete excision. There are few da... more Osteoblastoma is a rare primary bone tumor that is curable by complete excision. There are few data about the effectiveness of chemotherapy or radiotherapy in the treatment of recurrent osteoblastoma. We report a 13-year-old girl wit recurrent osteoblastoma who, after in complete surgical excision, responded to treatment with radiotherapy and later with chemotherapy. Surgery remains the treatment of choice for osteoblastoma. Radiotherapy and chemotherapy either alone or together may be useful in selected patients with recurrent, aggressive tumor or in patients with surgically unresectable disease.
Forty-four pathologic specimens of 39 bladder cancer patients were analyzed immunohistochemically... more Forty-four pathologic specimens of 39 bladder cancer patients were analyzed immunohistochemically with D07 monoclonal antibody to detect over-expression of mutant p53 gene. The findings were interpreted by correlating with patient age, sex, cigarette smoking, number and macroscopic appearance of tumour, histological tumour grade, muscular invasion, vascular invasion, necrosis and urothelial atypia or dysplasia. Mutant p53 gene was over-expressed in 8 (18.2%) specimens. Statistically significant correlation with grade, vascular invasion, necrosis and patient sex was found with p53 over-expression. Available follow-up data were insufficient to draw a conclusion about the prognostic role of p53 over-expression. Prospective studies with larger number of patients are needed to define the exact place of nuclear p53 over-expression in transitional cell bladder cancer.
It is difficult to recognize epithelioid trophoblastic tumor (ETT) as a trophoblastic disease bec... more It is difficult to recognize epithelioid trophoblastic tumor (ETT) as a trophoblastic disease because of its rarity and growth pattern simulating a carcinoma. A 36-year-old woman with stage IB(1) squamous cell carcinoma of the uterine cervix and a high serum beta-human chorionic gonadotropin (beta-hCG) level underwent radical hysterectomy with pelvic and para-aortic lymphadenectomy. However, light microscopic findings and immunohistochemical studies with pan-cytokeratin, epithelial membrane antigen, inhibin-alpha, beta-hCG, and human placental lactogen revealed ETT of the endocervix. The patient is alive with no evidence of disease 12 months after surgery. Before the patient is resorted to radical surgical interventions for assumed cervical carcinoma, ETT should be ruled out in women of reproductive age with endocervical tumors and elevated serum beta-hCG levels.
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