Pilonidal sinus is a worldwide problem found commonly in young hirsute men. The incidence is obse... more Pilonidal sinus is a worldwide problem found commonly in young hirsute men. The incidence is observed to be 26/100,000 person with 3:1 male predominance. This disease clinically simulates Nadivrana (K14) described in Ayurveda. Many surgical techniques have been described and performed as a treatment for chronic pilonidal sinus. But up to 40% of patients develop recurrence and surgery may cause loss of the intergluteal tissue and other side effects. A 29-year-old non-smoker, nonalcoholic male student with complaints of a dimple-like depression on the skin surface at upper part of intergluteal cleft associated with pain while sitting or standing, and intermittent discharge of foul-smelling pus and blood draining from the cleft visited the OPD of Central Ayurveda Research Institute for Cardiovascular Diseases, New Delhi for Ayurvedic management. On examination, there was swollen hyperemic skin around the area which is tender on palpation with hair protruding from the lesion and one vis...
It is today's need to understand the nanotechnology of manufacturing the ancient conventional... more It is today's need to understand the nanotechnology of manufacturing the ancient conventional drugs which advantages will certainly be more fruitful when reevaluate the standardization of manufacturing process of conventional medicine. As conventional medicine is having a potential risk of interactions between micronutrients affecting absorption and bioavailability. The antimicrobial action of Teminalia chebula especially on gastrointestinal tract is considered in supplementation of soothing to mucosal lining. Haritaki (Terminalia chebula), a common herbaceous plant is extensively used in preparation of many Ayurvedic medicines. Haritaki is used as a purgative, for flatulence, indigestion, gastroenteritis and Vata Dosha. Ellagic acid present in T. chebula has a potent inhibitory action on microorganisms like C. perfringens and E. coli. It is commonly advocated for increasing the gastrointestinal motility thus relieving the symptoms of gastroparesis for better bioavailability and...
AYU (An international quarterly journal of research in Ayurveda), 2016
Salacia species plant has been used traditionally as an Ayurvedic medicine for diabetes mellitus.... more Salacia species plant has been used traditionally as an Ayurvedic medicine for diabetes mellitus. Studies over the past decades have shown its multi-targeted role in diabetics. In the present review article, various mechanisms of action of Salacia on diabetics are discussed in detail. Apart from the well-known action of decreasing postprandial glucose sugar by inhibiting α-glucosidase and α-pancreatic amylase, it also inhibits aldose reductase which otherwise results in microvascular complications. Importantly, its peroxisome proliferator-activated receptor (PPAR)-γ agonist (such as thiazolidinediones, the insulin sensitizers) action increases the uptake of free fatty acid (FFA) and facilitates their storage in subcutaneous fat rather than the visceral fat. This reduces plasma FFA and insulin resistance. Furthermore, it increases the expression of and translocation to the cell surface of glucose transporter 1 and 4 receptors which result in glucose uptake by the liver and skeletal muscle and decreases plasma glucose levels. It also decreases inflammatory cytokines and increases adiponectin expression. Salacia as PPAR-α agonist (such as fibrates) has a role in the management of dyslipidemia. The activation of PPAR-α leads to the increased expression of lipoprotein lipase and apolipoprotein (Apo) A-V and decrease in hepatic Apo-C-III. These actions lower plasma triglycerides in chylomicrons and very low-density lipoprotein particles, thus liberating fatty acids, which are taken up and stored as fat in adipocytes. Salacia has been shown to suppress the overexpression of cardiac PPAR-α (similar to angiotensin-converting enzyme inhibitors/angiotensin receptor blockers) and thereby preventing diabetic cardiomyopathy. It also suppresses the cardiac angiotensin II Type 1 receptors resulting in antihypertrophic and antifibrogenic effect.
Shonitarsha is a common affliction which has been described and treated since the beginning of hu... more Shonitarsha is a common affliction which has been described and treated since the beginning of human civilization. Hemorrhoidal cushions are a part of normal anatomy but become pathological when swollen or inflamed. Treatment of piles in modern medicine is hemorrhoidectomy which results in repeated recurrences. Ayurveda provides a cure and prevents recurrences. Present study was carried out using a combination of Apamarga Kshara Basti and Triphalaguggulu. The results of the clinical assessment of the indigenous formulation on 129 patients with bleeding piles are reported in this paper; 55 patients of a total of 129 showed marked relief.
Pilonidal sinus is a worldwide problem found commonly in young hirsute men. The incidence is obse... more Pilonidal sinus is a worldwide problem found commonly in young hirsute men. The incidence is observed to be 26/100,000 person with 3:1 male predominance. This disease clinically simulates Nadivrana (K14) described in Ayurveda. Many surgical techniques have been described and performed as a treatment for chronic pilonidal sinus. But up to 40% of patients develop recurrence and surgery may cause loss of the intergluteal tissue and other side effects. A 29-year-old non-smoker, nonalcoholic male student with complaints of a dimple-like depression on the skin surface at upper part of intergluteal cleft associated with pain while sitting or standing, and intermittent discharge of foul-smelling pus and blood draining from the cleft visited the OPD of Central Ayurveda Research Institute for Cardiovascular Diseases, New Delhi for Ayurvedic management. On examination, there was swollen hyperemic skin around the area which is tender on palpation with hair protruding from the lesion and one vis...
It is today's need to understand the nanotechnology of manufacturing the ancient conventional... more It is today's need to understand the nanotechnology of manufacturing the ancient conventional drugs which advantages will certainly be more fruitful when reevaluate the standardization of manufacturing process of conventional medicine. As conventional medicine is having a potential risk of interactions between micronutrients affecting absorption and bioavailability. The antimicrobial action of Teminalia chebula especially on gastrointestinal tract is considered in supplementation of soothing to mucosal lining. Haritaki (Terminalia chebula), a common herbaceous plant is extensively used in preparation of many Ayurvedic medicines. Haritaki is used as a purgative, for flatulence, indigestion, gastroenteritis and Vata Dosha. Ellagic acid present in T. chebula has a potent inhibitory action on microorganisms like C. perfringens and E. coli. It is commonly advocated for increasing the gastrointestinal motility thus relieving the symptoms of gastroparesis for better bioavailability and...
AYU (An international quarterly journal of research in Ayurveda), 2016
Salacia species plant has been used traditionally as an Ayurvedic medicine for diabetes mellitus.... more Salacia species plant has been used traditionally as an Ayurvedic medicine for diabetes mellitus. Studies over the past decades have shown its multi-targeted role in diabetics. In the present review article, various mechanisms of action of Salacia on diabetics are discussed in detail. Apart from the well-known action of decreasing postprandial glucose sugar by inhibiting α-glucosidase and α-pancreatic amylase, it also inhibits aldose reductase which otherwise results in microvascular complications. Importantly, its peroxisome proliferator-activated receptor (PPAR)-γ agonist (such as thiazolidinediones, the insulin sensitizers) action increases the uptake of free fatty acid (FFA) and facilitates their storage in subcutaneous fat rather than the visceral fat. This reduces plasma FFA and insulin resistance. Furthermore, it increases the expression of and translocation to the cell surface of glucose transporter 1 and 4 receptors which result in glucose uptake by the liver and skeletal muscle and decreases plasma glucose levels. It also decreases inflammatory cytokines and increases adiponectin expression. Salacia as PPAR-α agonist (such as fibrates) has a role in the management of dyslipidemia. The activation of PPAR-α leads to the increased expression of lipoprotein lipase and apolipoprotein (Apo) A-V and decrease in hepatic Apo-C-III. These actions lower plasma triglycerides in chylomicrons and very low-density lipoprotein particles, thus liberating fatty acids, which are taken up and stored as fat in adipocytes. Salacia has been shown to suppress the overexpression of cardiac PPAR-α (similar to angiotensin-converting enzyme inhibitors/angiotensin receptor blockers) and thereby preventing diabetic cardiomyopathy. It also suppresses the cardiac angiotensin II Type 1 receptors resulting in antihypertrophic and antifibrogenic effect.
Shonitarsha is a common affliction which has been described and treated since the beginning of hu... more Shonitarsha is a common affliction which has been described and treated since the beginning of human civilization. Hemorrhoidal cushions are a part of normal anatomy but become pathological when swollen or inflamed. Treatment of piles in modern medicine is hemorrhoidectomy which results in repeated recurrences. Ayurveda provides a cure and prevents recurrences. Present study was carried out using a combination of Apamarga Kshara Basti and Triphalaguggulu. The results of the clinical assessment of the indigenous formulation on 129 patients with bleeding piles are reported in this paper; 55 patients of a total of 129 showed marked relief.
Uploads