The exact nature of the complex relationship between sleep and affect has remained unclear. This ... more The exact nature of the complex relationship between sleep and affect has remained unclear. This study investigated the temporal order of change in sleep and affect in participants with and without depression. 27 depressed patients and 27 pair-matched healthy controls assessed their sleep in the morning and their affect 3 times a day for 30 consecutive days in their natural environment. Daily sleep quality and average positive affect (PA) and negative affect (NA) were used to examine whether changes in sleep quality preceded or followed changes in PA and NA, and whether this was different for patients and healthy controls. Second, presumptive mediating factors were investigated. We hypothesized that fatigue mediated the effect of changes in sleep quality on subsequent PA/NA, and that rumination mediated the effect of changes in PA/NA on subsequent sleep quality. Multilevel models showed that changes in sleep quality predicted changes in PA (B=0.08, p<0.001) and NA (B=-0.06, p<...
All over the world people are becoming increasingly interested in complementary and alternative m... more All over the world people are becoming increasingly interested in complementary and alternative medicine (CAM). Some would like CAM to be integrated into conventional medicine, others are strongly opposed to its integration. We distributed printed questionnaires in order to discover the views of patients and psychiatrists on CAM and to obtain information about the extent to which people actually use CAM. Patients often turn to CAM and are generally satisfied with the results and many support integration. Psychiatrists underestimate the number of times that patients use CAM. They are reluctant to support the integration of alternative medicine but are less opposed to the integration of complementary medicine. Patients and psychiatrists want more information about CAM. Asking the patients whether they use CAM seems desirable.
Time-series analysis was used to study the associations between daily weather variables and sympt... more Time-series analysis was used to study the associations between daily weather variables and symptomatology in a man suffering from recurrent anxiety. Outcome measures were the patient's main symptoms: anxiety and energy. Wind direction appeared to be related to the patient's energy levels; these were significantly lower when the wind blew from the southeast. This effect could not be explained by other weather parameters. Decreases in energy in turn predicted increases in anxiety. The reverse effect was observed as well, with increases in anxiety predicting decreases in energy, indicating a positive feedback loop.
All over the world people are becoming increasingly interested in complementary and alternative m... more All over the world people are becoming increasingly interested in complementary and alternative medicine (CAM). Some would like CAM to be integrated into conventional medicine, others are strongly opposed to its integration. We distributed printed questionnaires in order to discover the views of patients and psychiatrists on CAM and to obtain information about the extent to which people actually use CAM. Patients often turn to CAM and are generally satisfied with the results and many support integration. Psychiatrists underestimate the number of times that patients use CAM. They are reluctant to support the integration of alternative medicine but are less opposed to the integration of complementary medicine. Patients and psychiatrists want more information about CAM. Asking the patients whether they use CAM seems desirable.
There is considerable debate about routine outcome monitoring (ROM) for scientific or benchmarkin... more There is considerable debate about routine outcome monitoring (ROM) for scientific or benchmarking purposes. We discuss pitfalls associated with the assessment , analysis, and interpretation of ROM data, using data of 376 patients. 206 patients (55 %) completed one or more follow-up measurements. Mixed-model analysis showed significant improvement in symptomatology, quality of life, and autonomy, and differential improvement for different subgroups. Effect sizes were small to large, depending on the outcome measure and subgroup. Subtle variations in analytic strategies influenced effect sizes substantially. We illustrate how problems inherent to design and analysis of ROM data prevent drawing conclusions about (comparative) treatment effectiveness.
The exact nature of the complex relationship between sleep and affect has remained unclear. This ... more The exact nature of the complex relationship between sleep and affect has remained unclear. This study investigated the temporal order of change in sleep and affect in participants with and without depression. 27 depressed patients and 27 pair-matched healthy controls assessed their sleep in the morning and their affect 3 times a day for 30 consecutive days in their natural environment. Daily sleep quality and average positive affect (PA) and negative affect (NA) were used to examine whether changes in sleep quality preceded or followed changes in PA and NA, and whether this was different for patients and healthy controls. Second, presumptive mediating factors were investigated. We hypothesized that fatigue mediated the effect of changes in sleep quality on subsequent PA/NA, and that rumination mediated the effect of changes in PA/NA on subsequent sleep quality. Multilevel models showed that changes in sleep quality predicted changes in PA (B=0.08, p<0.001) and NA (B=-0.06, p<...
All over the world people are becoming increasingly interested in complementary and alternative m... more All over the world people are becoming increasingly interested in complementary and alternative medicine (CAM). Some would like CAM to be integrated into conventional medicine, others are strongly opposed to its integration. We distributed printed questionnaires in order to discover the views of patients and psychiatrists on CAM and to obtain information about the extent to which people actually use CAM. Patients often turn to CAM and are generally satisfied with the results and many support integration. Psychiatrists underestimate the number of times that patients use CAM. They are reluctant to support the integration of alternative medicine but are less opposed to the integration of complementary medicine. Patients and psychiatrists want more information about CAM. Asking the patients whether they use CAM seems desirable.
Time-series analysis was used to study the associations between daily weather variables and sympt... more Time-series analysis was used to study the associations between daily weather variables and symptomatology in a man suffering from recurrent anxiety. Outcome measures were the patient's main symptoms: anxiety and energy. Wind direction appeared to be related to the patient's energy levels; these were significantly lower when the wind blew from the southeast. This effect could not be explained by other weather parameters. Decreases in energy in turn predicted increases in anxiety. The reverse effect was observed as well, with increases in anxiety predicting decreases in energy, indicating a positive feedback loop.
All over the world people are becoming increasingly interested in complementary and alternative m... more All over the world people are becoming increasingly interested in complementary and alternative medicine (CAM). Some would like CAM to be integrated into conventional medicine, others are strongly opposed to its integration. We distributed printed questionnaires in order to discover the views of patients and psychiatrists on CAM and to obtain information about the extent to which people actually use CAM. Patients often turn to CAM and are generally satisfied with the results and many support integration. Psychiatrists underestimate the number of times that patients use CAM. They are reluctant to support the integration of alternative medicine but are less opposed to the integration of complementary medicine. Patients and psychiatrists want more information about CAM. Asking the patients whether they use CAM seems desirable.
There is considerable debate about routine outcome monitoring (ROM) for scientific or benchmarkin... more There is considerable debate about routine outcome monitoring (ROM) for scientific or benchmarking purposes. We discuss pitfalls associated with the assessment , analysis, and interpretation of ROM data, using data of 376 patients. 206 patients (55 %) completed one or more follow-up measurements. Mixed-model analysis showed significant improvement in symptomatology, quality of life, and autonomy, and differential improvement for different subgroups. Effect sizes were small to large, depending on the outcome measure and subgroup. Subtle variations in analytic strategies influenced effect sizes substantially. We illustrate how problems inherent to design and analysis of ROM data prevent drawing conclusions about (comparative) treatment effectiveness.
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Papers by Rogier Hoenders