The use of urea as an osmotic agent for the reduction of intraocular pressure has supplanted sucr... more The use of urea as an osmotic agent for the reduction of intraocular pressure has supplanted sucrose and the other drugs classically used for this purpose. The theoretical advantages of urea have been outlined, 1 but no comparative study of urea and sucrose that might adduce clinical proof of these advantages has appeared in the literature. Recently, however, it was possible to obtain a patient, a 70-year-old man, on whom a comparison of the effects of intravenously administered urea and sucrose in the commonly used dosage levels could be measured. The results are reported herein. Materials and Methods As in past studies, the following routine was used: Blood was obtained for subsequent analysis of freezing point depression and urea nitrogen. Tonography was performed, and shortly thereafter a 30% solution of lyophilized, ammonia-free urea * dissolved in 10% invert sugar was administered intravenously at a rate of about 3 cc. per minute.
Background/aimsWith a paradigm shift in geographic atrophy (GA) treatments now available, establi... more Background/aimsWith a paradigm shift in geographic atrophy (GA) treatments now available, establishing consensus on the identification and diagnosis of the disease along with considerations for management of patients with GA will assist eye care professionals (ECP) in their day-to-day practices, leading to improved patient outcomes.MethodsA modified Delphi panel process (Geographic Atrophy Management Consensus) consisting of three total surveys and one virtual live meeting held between survey 2 and survey 3. Data were collected from July to October 2022. Participants included expert members of the eye care community that have demonstrated outstanding leadership among peers: a steering committee with three ECPs and a 15-member panel divided between five optometrists, five comprehensive ophthalmologists and five retina specialists. Consensus on statements related to the management of patients with GA was calculated using the RAND/UCLA Appropriateness Method.ResultsAt the conclusion of...
Journal of refractive surgery (Thorofare, N.J. : 1995), 2018
To report a retrospective study of simultaneous LASIK versus photorefractive keratectomy (PRK) wi... more To report a retrospective study of simultaneous LASIK versus photorefractive keratectomy (PRK) with accompanying small-aperture cornea inlay implantation (KAMRA; AcuFocus, Inc., Irvine, CA) in treating presbyopia. Simultaneous LASIK/inlay and simultaneous PRK/inlay was performed on 79 and 47 patients, respectively. Follow-up examinations were conducted at 1, 3, and 6 months postoperatively. The main outcome measures were safety, efficacy, predictability, and stability with primary emphasis on monocular uncorrected near visual acuity (UNVA). Both groups met U.S. Food and Drug Administration criteria for efficacy with 95% and 55% of the LASIK/inlay group and 83% and 52% of the PRK/inlay group having a monocular UNVA of 20/40 (J5) and 20/25 (J2), respectively, at 6-month follow-up. Ninety-two percent of the LASIK/inlay group and 95% of the PRK/inlay group had a UDVA of 20/40 or better at 6 months. Two eyes lost one line of corrected distance visual acuity (CDVA). Mild hyperopic shift w...
The use of urea as an osmotic agent for the reduction of intraocular pressure has supplanted sucr... more The use of urea as an osmotic agent for the reduction of intraocular pressure has supplanted sucrose and the other drugs classically used for this purpose. The theoretical advantages of urea have been outlined, 1 but no comparative study of urea and sucrose that might adduce clinical proof of these advantages has appeared in the literature. Recently, however, it was possible to obtain a patient, a 70-year-old man, on whom a comparison of the effects of intravenously administered urea and sucrose in the commonly used dosage levels could be measured. The results are reported herein. Materials and Methods As in past studies, the following routine was used: Blood was obtained for subsequent analysis of freezing point depression and urea nitrogen. Tonography was performed, and shortly thereafter a 30% solution of lyophilized, ammonia-free urea * dissolved in 10% invert sugar was administered intravenously at a rate of about 3 cc. per minute.
Background/aimsWith a paradigm shift in geographic atrophy (GA) treatments now available, establi... more Background/aimsWith a paradigm shift in geographic atrophy (GA) treatments now available, establishing consensus on the identification and diagnosis of the disease along with considerations for management of patients with GA will assist eye care professionals (ECP) in their day-to-day practices, leading to improved patient outcomes.MethodsA modified Delphi panel process (Geographic Atrophy Management Consensus) consisting of three total surveys and one virtual live meeting held between survey 2 and survey 3. Data were collected from July to October 2022. Participants included expert members of the eye care community that have demonstrated outstanding leadership among peers: a steering committee with three ECPs and a 15-member panel divided between five optometrists, five comprehensive ophthalmologists and five retina specialists. Consensus on statements related to the management of patients with GA was calculated using the RAND/UCLA Appropriateness Method.ResultsAt the conclusion of...
Journal of refractive surgery (Thorofare, N.J. : 1995), 2018
To report a retrospective study of simultaneous LASIK versus photorefractive keratectomy (PRK) wi... more To report a retrospective study of simultaneous LASIK versus photorefractive keratectomy (PRK) with accompanying small-aperture cornea inlay implantation (KAMRA; AcuFocus, Inc., Irvine, CA) in treating presbyopia. Simultaneous LASIK/inlay and simultaneous PRK/inlay was performed on 79 and 47 patients, respectively. Follow-up examinations were conducted at 1, 3, and 6 months postoperatively. The main outcome measures were safety, efficacy, predictability, and stability with primary emphasis on monocular uncorrected near visual acuity (UNVA). Both groups met U.S. Food and Drug Administration criteria for efficacy with 95% and 55% of the LASIK/inlay group and 83% and 52% of the PRK/inlay group having a monocular UNVA of 20/40 (J5) and 20/25 (J2), respectively, at 6-month follow-up. Ninety-two percent of the LASIK/inlay group and 95% of the PRK/inlay group had a UDVA of 20/40 or better at 6 months. Two eyes lost one line of corrected distance visual acuity (CDVA). Mild hyperopic shift w...
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Papers by Ronald Rebenitsch