Proceedings of the Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia, 2019
Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and anti... more Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which is possibly related to fatigue and tissue injury. Red fruit oil contains high betacarotene and tocopherol. This study was investigated the effect of red fruit oil on hematological parameters and endurance performance at maximal physical activity. This study was used pretestposttest control group design. Thirty athletes are used as samples were divided into two groups. While undergoing the training program, the experimental group consumed the red fruit oil 5 ml every day. After undergoing the training program, all athletes perform maximum physical activity by doing a bleep test. Blood samples were collected before and after the test to measure hematological parameters. The result of the research was concluded that red fruit oil can affect hematological parameters and increase endurance and delay fatigue induced by maximal physical activity in athletes.
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2020
Obesitas dapat menyebabkan peningkatan kolesterol dan trigliserida yang dapat menyebabkan penyaki... more Obesitas dapat menyebabkan peningkatan kolesterol dan trigliserida yang dapat menyebabkan penyakit kardiovascular. Tujuan penelitian adalah untuk mengetahui pengaruh senam aerobik mix impact dan suplementasi bawang putih terhadap penurunan kadar kolesterol total dan kadar trigliserida wanita penderita obesitas. Jenis penelitian adalah penelitian eksperimental semu dengan rancangan penelitian pretest postets control group design. Sampel penelitian berjumlah 10 orang dibagi atas dua kelompok yaitu kelompok senam aerobik mix impact (SA) sebagai kelompok kontrol dan kelompok senam aerobik mix impact dengan suplementasi bawang putih (LA-BP) sebagai kelompok eksperimen. Senam aerobik dilakukan selama satu bulan, 3 kali seminggu, waktu 45 menit dengan target denyut jantung 60-70% MHR, sedang pemberian bawang putih adalah satu kali satu hari. Hasil penelitian diperoleh kadar kolesterol total pretest kelompok LA dan LA-BP adalah 212,9 mg/dl dan 215,6 mg/dl, kadar trigliserida 106,1 mg/dl da...
Physical activity can cause to increased production of free radicals that can be reduced the anti... more Physical activity can cause to increased production of free radicals that can be reduced the antioxidant so as to affect performance athletes due to happened sport anemia. Free radicals can be prevented or reduced to the delivery of antioxidant. It have been known fruit red guava containing various types of natural antioxidant but never researched for its usefulness to reduce free radical production triggered by physical activity. This study aims to know the effect of giving guava fruit juice towards haemoglobin and VO2max contents on maximum physical activity. Type of this study was experimental research with Randomized Control Group Pretest Design. It was conducted at Medan State University Stadium and Physiology Laboratory Faculty Of Sport Science, Medan State University. It was conducted in 3 Months. The population and sample were 20 students of sport which fulfilled the criteria and it was divided into group, namely experimental group and control group. In this study was conduc...
Maximum physical activity can cause an increase in malondialdehyde levels due to increased produc... more Maximum physical activity can cause an increase in malondialdehyde levels due to increased production of free radicals. The amount of free radicals can be neutralized by giving antioxidants. Red guava fruit is known to have high antioxidant content. The purpose of this study was to determine the effect of giving red guava during exercise on malondialdehyde levels when performing maximum physical activity. This research is an experimental research with a randomized control group pretest-posttest design. The study was conducted at the Physical Laboratory of the Faculty of Sport Sciences, State University of Medan. The population and sample were students of Sports Science as many as 20 people who met the criteria. Sample was divided into 2 groups, namely the group that consumed red guava fruit juice (RGF) during the exercise program and the control group (C). Malondialdehyde examination was carried out before the administration of red guava gruit juice and after maximum physical activi...
This study investigated the effect of red fruit oil on biomarkers of oxidative stress in maximal ... more This study investigated the effect of red fruit oil on biomarkers of oxidative stress in maximal physical activity. Fourty rats were divided into 4 groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III) and (IV) were administered with different doses of Red Fruit Oil (0.15 ml/kgBW, 0.3 ml/kgBW, and 0.6 ml/kgBW, respectively). All groups were trained to swim for 4 weeks and then were forced to swim without a load until being exhausted. The malondialdehyde, glutathione peroxidase levels and time of swimming to exhaustion were measured in all groups. The results showed that MDA level obtained was decreasing significantly (P<0.05), glutathione peroxidase and time of swimming was increasing significantly (P< 0.05) in the intervention groups. The results suggest that red fruit oil can obviously reduce MDA level, increased glutathione peroxidase and endurance and delay fatigue induced by maximal physical activity in the rat. Keywor...
Asian Journal of Pharmaceutical Research and Development, 2020
Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha in... more Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated. Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing. Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base. Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase. Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.
Open Access Macedonian Journal of Medical Sciences, 2020
BACKGROUND: Living cells continuously produce free radicals and reactive oxygen species (ROS) as ... more BACKGROUND: Living cells continuously produce free radicals and reactive oxygen species (ROS) as a part of metabolic processes. These free radicals are neutralized by an antioxidant defense system. Maximal physical activity can produce an imbalance between ROS and antioxidants and thus may cause oxidative stress, which is possibly related to fatigue and tissue injury. Red fruit oil contains high beta-carotene and tocopherol as antioxidants which could overcome oxidative stress condition. AIM: The aim of this study was to determine the effect of red fruit oil on exercise endurance and oxidative stress in rats at a maximal physical activity. METHODS: Twenty-four male rats were divided into four groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III), and (IV) were administered with different doses of red fruit oil (0.15 ml/kgBW, 0.3 ml/kgBW, and 0.6 ml/kgBW, respectively). All groups were trained to swim for 4 weeks and then were for...
The purpose of this study was to determine the protective effects of beetroot juice treatment on ... more The purpose of this study was to determine the protective effects of beetroot juice treatment on hepatic oxidative stress at maximum physical activity. This type of research is an experimental study with a randomized control group pretest-posttest design research. The study was conducted at the Universitas Negeri Medan Stadium and Universitas Sumatera Utara Faculty of Medicine Laboratory. The sample was 30 students of Sports Science who met the criteria. The Pretest is done by checking the levels of alanine aminotransferase, aspartate aminotransferase, and malondialdehyde. Furthermore the sample was divided into 2 groups (P1 = 15, P2 = 15). During the 30-day training program, the P1 group was given 250 ml beetroot juice once a day, whereas P2 was given as a control. Then all samples performed a maximal physical activity using a bleep test, and again examined levels of alanine aminotransferase, aspartate aminotransferase, and malondialdehyde. The results showed beetroot juice could r...
Open Access Macedonian Journal of Medical Sciences, 2019
BACKGROUND: Maximal physical activity can produce an imbalance between reactive oxygen species (R... more BACKGROUND: Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which are possibly related to fatigue and tissue injury. One of the natural sources that contain antioxidants is virgin coconut oil (VCO). AIM: This study aimed to determine the protective effects antioxidant of virgin coconut oil (VCO) treatment on urea and creatine level on maximum physical activity METHODS: This study used 24 healthy male rats. The rats were divided into four groups, randomly consisted of six rats in each group. The control group (P0) was given 2 mL water, the treatment groups (VCO-1, VCO-2, and VCO-4) were given VCO 1 mL/200 gBW, 2 mL/200 gBW and 4 ml/200 gBW, respectively, per day using gavage spuit. After 28 days, the rats were forced to perform maximal activity by putting the rats in water with no exit. Blood samples were collected immediately after the maximum physical activity. The urea, creatinine, malondialdehyde and glutation peroxidase l...
Asian Journal of Pharmaceutical and Clinical Research, 2019
Objective: The purpose of this study was to determine the protective effects of virgin coconut oi... more Objective: The purpose of this study was to determine the protective effects of virgin coconut oil (VCO) treatment on hepatic oxidative stress and antioxidant defenses after maximum physical activity. Methods: This study used 24 healthy male rats. The rats were divided into four groups randomly consisted of six rats in each group. The control group (P0) was given 2 mL water, the treatment groups (VCO-1, VCO-2, and VCO-4) were given VCO 1 ml/200 g BW, 2 ml/200 g BW, and 4 ml/200 g BW, respectively, per day using gavage spuit. The rats were trained to swim for a month, 30 min/day in the 1st week, 35 min/day in the 2nd week, 40 min/ day in the 3rd week, and 45 min/day in the 4th week. After 28 days, the rats were forced to perform the maximal activity by putting the rats in water with no exit. Blood samples were collected immediately after the maximum physical activity, and then, all rats were killed and liver tissues were collected. The malondialdehyde (MDA), glutathione peroxidase (G...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2017
Aktivitas fisik berat maupun olahraga aerobik dapat meningkatkan konsumsi oksigen dalam tubuh 10... more Aktivitas fisik berat maupun olahraga aerobik dapat meningkatkan konsumsi oksigen dalam tubuh 10-20 kali dan 100-200 kali lipat pada otot. Peningkatan penggunaan oksigen akibat peningkatan aktifitas dapat meningkatkan produksi radikal yang dapat mempengaruhi performance atlet ditandai dengan turunnya Hb. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian vitamin E terhadap kadar hemoglobin pada aktifitas fisik maksimal mahasiswa Ilmu Keolahragaan FIK Unimed.Jenis penelitian yang dilakukan adalah penelitian eksperimental semu dengan rancangan penelitian Randomized Control Group Pretest-Postest Design. Penelitian dilaksanakan di Stadion Sepakbola dan Laboratorium Fisiologi FIK UNIMED. Penelitian dilakukan selama 2 bulan dengan populasi dan sampel mahasiswa Ilmu Keolahragaan yang memenuhi kriteria. Pada penelitian ini akan diukur kadar Haemoglobin sebelum dan sesudah mengkonsumsi Vitamin E dengan dosis 400mg setelah melakukan aktifitas fisik maksimalDari hasil ana...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2019
Prevalensi obesitas dari tahun ke tahun mengalami peningkatan yang dapat membahayakan kesehatan t... more Prevalensi obesitas dari tahun ke tahun mengalami peningkatan yang dapat membahayakan kesehatan terutama penyakit cardiovascular yang ditandai dengan peningkatan Indeks Massa Tubuh (IMT) dan kadar kolesterol. Tujuan penelitian adalah untuk mengetahui pengaruh senam aerobik intensitas sedang terhadap penurunan Indeks Massa Tubuh dan kadar total kolesterol pada wanita penderita obesitas. Jenis penelitian adalah penelitian eksperimental semu dengan rancangan penelitian one group pretest postets design. Sampel penelitian berjumlah 10 orang yang sudah memenuhi kriteria. Senam aerobik dilakukan selama satu bulan, 3 kali seminggu, waktu 50 menit dengan target denyut jantung 60-70% MHR. Pengukuran IMT dan kolesterol total dilakukan sebelum dimulai program latihan dan setelah dan setelah menjalani program latihan senam aerobik. Hasil penelitian diperoleh IMT dan kadar kolesterol total pretest adalah 39,61 kg/m2 dan 191,1 mg/dl. Kadar IMT dan kadar kolesterol total postest adalah 24,81 kg/m2...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2019
Aktifitas fisik maksimal dapat mempengaruhi kesehatan dan performance atlet akibat meningkatnya p... more Aktifitas fisik maksimal dapat mempengaruhi kesehatan dan performance atlet akibat meningkatnya produksi radikal bebas di dalam tubuh. Tujuan penelitian adalah untuk mengetahui pengaruh aktifitas fisik maksimal terhadap jumlah leukosit dan hitung jenis leukosit pada Atlet Softball Putri Universitas Negeri Medan. Penelitian ini menggunakan metode quasi eksperimen dengan rancangan penelitian one group pretest posttest. Jumlah sampel berjumlah 11 orang. Pengukuran kadar leukosit dan hitung jenis leukosit dilakukan sebelum dan setelah melakukan aktifitas fisik maksimal. Hasil penelitian diperoleh rerata jumlah leukosit pretest 8,37 dan posttest sebesar 13,03; rerata jumlah neutrofil pretest 56,45 dan posttest 46,27; rerata jumlah limfosit pretest 33,27 dan posttest 42,90; rerata monosit pretest 6,45 dan posttest 7,63; rerata jumlah eusinofil pretest 3,81 dan posttest 3,18. Hasil uji-t berpasangan menunjukan bahwa aktifitas fisik maksimal dapat meningkatkan jumlah leukosit dan limfosit s...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2019
Aktifitas fisik berat dapat mengakibatkan terjadi stress oksidatif yang berdampak kepada penuruna... more Aktifitas fisik berat dapat mengakibatkan terjadi stress oksidatif yang berdampak kepada penurunan performance dan kesehatan atlet. Stres oksidatif dapat dicegah atau dikurangi dengan pemberian antioksidan. Salah satu sumber alami yang mengandung antioksidan adalah minyak buah merah (MBM). Sebagai antioksidan MBM diklaim mempunyai banyak khasiat tetapi semua efek ini masih perlu pembuktian secara ilmiah. Tujuan penelitian adalah untuk untuk melihat pengaruh pemberian MBM terhadap kadar Serum Glutamic Oxaloacetic Transaminase (SGPT) dan serum glutamate piruvat transferase serum tikus pada aktifitas fisik maksimal. Jenis penelitian yang dilakukan adalah penelitian eksperimental dengan rancangan penelitian randomized control group postest only group design. Penelitian dilakukan di Laboratorium Farmakologi Fakultas Farmasi Universitas Sumatera Utara. Penelitian menggunakan 40 ekor tikus yang dibagi menjadi empat kelompok yaitu kelompok kontrol (C); E-15; E-30 dan E-60 masing-masing d...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2018
Aktifitas fisik dapat menyebabkan peningkatan produksi radikal bebas yang menyebabkan terjadi str... more Aktifitas fisik dapat menyebabkan peningkatan produksi radikal bebas yang menyebabkan terjadi stress oksidatif akibat jumlah radikal bebas melebihi jumlah antioksidan tubuh. Stres oksidatif dapat menyebabkan peningkatan jumlah leukosit. Jumlah leukosit perifer dapat menjadi sumber informasi untuk diagnosa dan prognosa serta gambaran kerusakan organ dan pemulihan setelah olahraga. Radikal bebas dapat dicegah atau dikurangi dengan pemberian antioksidan. Telah diketahui buah jambu biji merah mengandung antioksidan. Tujuan penelitian adalah untuk mengetahui pengaruh pemberian jus buah jambu biji merah terhadap jumlah leukosit pada aktifitas fisik maksimal. Jenis penelitian yang dilakukan adalah penelitian eksperimental dengan rancangan penelitian randomized control group pretest-postest design. Sampel penelitian adalah mahasiswa Ilmu Keolahragaan sebanyak 30 orang yang memenuhi kriteria. Selanjutnya sampel dibagi atas 3 kelompok (P1=10, P2=10, dan P3=10). Selama menjalani program latiha...
Severe physical activity can cause lipid peroxidation marked by increased levels of malondialdehy... more Severe physical activity can cause lipid peroxidation marked by increased levels of malondialdehyde (MDA) which can reduce athlete's performance and health. Lipid peroxidation can be prevented or reduced by administering antioxidants. Beets (Beta Vulgaris L) contain various types of natural antioxidants but have not been investigated for their efficacy to reduce lipid peroxidation that is triggered by physical activity. The purpose of this study was to determine the effect of beetroot juice during exercise on lipid peroxidation during maximum physical activity.This type of research is an experimental study with a randomized control group pretestposttest design research design. The study was conducted at the Unimed Stadium and the USU Faculty of Medicine Integrated Laboratory. The sample was 30 students of Sports Science who met the criteria. Pretest is done by checking MDA levels. Furthermore the sample was divided into 2 groups (P1 = 15, P2 = 15). During the training program gr...
Proceedings of the Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia, 2019
Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and anti... more Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which is possibly related to fatigue and tissue injury. Red fruit oil contains high betacarotene and tocopherol. This study was investigated the effect of red fruit oil on hematological parameters and endurance performance at maximal physical activity. This study was used pretestposttest control group design. Thirty athletes are used as samples were divided into two groups. While undergoing the training program, the experimental group consumed the red fruit oil 5 ml every day. After undergoing the training program, all athletes perform maximum physical activity by doing a bleep test. Blood samples were collected before and after the test to measure hematological parameters. The result of the research was concluded that red fruit oil can affect hematological parameters and increase endurance and delay fatigue induced by maximal physical activity in athletes.
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2020
Obesitas dapat menyebabkan peningkatan kolesterol dan trigliserida yang dapat menyebabkan penyaki... more Obesitas dapat menyebabkan peningkatan kolesterol dan trigliserida yang dapat menyebabkan penyakit kardiovascular. Tujuan penelitian adalah untuk mengetahui pengaruh senam aerobik mix impact dan suplementasi bawang putih terhadap penurunan kadar kolesterol total dan kadar trigliserida wanita penderita obesitas. Jenis penelitian adalah penelitian eksperimental semu dengan rancangan penelitian pretest postets control group design. Sampel penelitian berjumlah 10 orang dibagi atas dua kelompok yaitu kelompok senam aerobik mix impact (SA) sebagai kelompok kontrol dan kelompok senam aerobik mix impact dengan suplementasi bawang putih (LA-BP) sebagai kelompok eksperimen. Senam aerobik dilakukan selama satu bulan, 3 kali seminggu, waktu 45 menit dengan target denyut jantung 60-70% MHR, sedang pemberian bawang putih adalah satu kali satu hari. Hasil penelitian diperoleh kadar kolesterol total pretest kelompok LA dan LA-BP adalah 212,9 mg/dl dan 215,6 mg/dl, kadar trigliserida 106,1 mg/dl da...
Physical activity can cause to increased production of free radicals that can be reduced the anti... more Physical activity can cause to increased production of free radicals that can be reduced the antioxidant so as to affect performance athletes due to happened sport anemia. Free radicals can be prevented or reduced to the delivery of antioxidant. It have been known fruit red guava containing various types of natural antioxidant but never researched for its usefulness to reduce free radical production triggered by physical activity. This study aims to know the effect of giving guava fruit juice towards haemoglobin and VO2max contents on maximum physical activity. Type of this study was experimental research with Randomized Control Group Pretest Design. It was conducted at Medan State University Stadium and Physiology Laboratory Faculty Of Sport Science, Medan State University. It was conducted in 3 Months. The population and sample were 20 students of sport which fulfilled the criteria and it was divided into group, namely experimental group and control group. In this study was conduc...
Maximum physical activity can cause an increase in malondialdehyde levels due to increased produc... more Maximum physical activity can cause an increase in malondialdehyde levels due to increased production of free radicals. The amount of free radicals can be neutralized by giving antioxidants. Red guava fruit is known to have high antioxidant content. The purpose of this study was to determine the effect of giving red guava during exercise on malondialdehyde levels when performing maximum physical activity. This research is an experimental research with a randomized control group pretest-posttest design. The study was conducted at the Physical Laboratory of the Faculty of Sport Sciences, State University of Medan. The population and sample were students of Sports Science as many as 20 people who met the criteria. Sample was divided into 2 groups, namely the group that consumed red guava fruit juice (RGF) during the exercise program and the control group (C). Malondialdehyde examination was carried out before the administration of red guava gruit juice and after maximum physical activi...
This study investigated the effect of red fruit oil on biomarkers of oxidative stress in maximal ... more This study investigated the effect of red fruit oil on biomarkers of oxidative stress in maximal physical activity. Fourty rats were divided into 4 groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III) and (IV) were administered with different doses of Red Fruit Oil (0.15 ml/kgBW, 0.3 ml/kgBW, and 0.6 ml/kgBW, respectively). All groups were trained to swim for 4 weeks and then were forced to swim without a load until being exhausted. The malondialdehyde, glutathione peroxidase levels and time of swimming to exhaustion were measured in all groups. The results showed that MDA level obtained was decreasing significantly (P<0.05), glutathione peroxidase and time of swimming was increasing significantly (P< 0.05) in the intervention groups. The results suggest that red fruit oil can obviously reduce MDA level, increased glutathione peroxidase and endurance and delay fatigue induced by maximal physical activity in the rat. Keywor...
Asian Journal of Pharmaceutical Research and Development, 2020
Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha in... more Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated. Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing. Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base. Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase. Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.
Open Access Macedonian Journal of Medical Sciences, 2020
BACKGROUND: Living cells continuously produce free radicals and reactive oxygen species (ROS) as ... more BACKGROUND: Living cells continuously produce free radicals and reactive oxygen species (ROS) as a part of metabolic processes. These free radicals are neutralized by an antioxidant defense system. Maximal physical activity can produce an imbalance between ROS and antioxidants and thus may cause oxidative stress, which is possibly related to fatigue and tissue injury. Red fruit oil contains high beta-carotene and tocopherol as antioxidants which could overcome oxidative stress condition. AIM: The aim of this study was to determine the effect of red fruit oil on exercise endurance and oxidative stress in rats at a maximal physical activity. METHODS: Twenty-four male rats were divided into four groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III), and (IV) were administered with different doses of red fruit oil (0.15 ml/kgBW, 0.3 ml/kgBW, and 0.6 ml/kgBW, respectively). All groups were trained to swim for 4 weeks and then were for...
The purpose of this study was to determine the protective effects of beetroot juice treatment on ... more The purpose of this study was to determine the protective effects of beetroot juice treatment on hepatic oxidative stress at maximum physical activity. This type of research is an experimental study with a randomized control group pretest-posttest design research. The study was conducted at the Universitas Negeri Medan Stadium and Universitas Sumatera Utara Faculty of Medicine Laboratory. The sample was 30 students of Sports Science who met the criteria. The Pretest is done by checking the levels of alanine aminotransferase, aspartate aminotransferase, and malondialdehyde. Furthermore the sample was divided into 2 groups (P1 = 15, P2 = 15). During the 30-day training program, the P1 group was given 250 ml beetroot juice once a day, whereas P2 was given as a control. Then all samples performed a maximal physical activity using a bleep test, and again examined levels of alanine aminotransferase, aspartate aminotransferase, and malondialdehyde. The results showed beetroot juice could r...
Open Access Macedonian Journal of Medical Sciences, 2019
BACKGROUND: Maximal physical activity can produce an imbalance between reactive oxygen species (R... more BACKGROUND: Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which are possibly related to fatigue and tissue injury. One of the natural sources that contain antioxidants is virgin coconut oil (VCO). AIM: This study aimed to determine the protective effects antioxidant of virgin coconut oil (VCO) treatment on urea and creatine level on maximum physical activity METHODS: This study used 24 healthy male rats. The rats were divided into four groups, randomly consisted of six rats in each group. The control group (P0) was given 2 mL water, the treatment groups (VCO-1, VCO-2, and VCO-4) were given VCO 1 mL/200 gBW, 2 mL/200 gBW and 4 ml/200 gBW, respectively, per day using gavage spuit. After 28 days, the rats were forced to perform maximal activity by putting the rats in water with no exit. Blood samples were collected immediately after the maximum physical activity. The urea, creatinine, malondialdehyde and glutation peroxidase l...
Asian Journal of Pharmaceutical and Clinical Research, 2019
Objective: The purpose of this study was to determine the protective effects of virgin coconut oi... more Objective: The purpose of this study was to determine the protective effects of virgin coconut oil (VCO) treatment on hepatic oxidative stress and antioxidant defenses after maximum physical activity. Methods: This study used 24 healthy male rats. The rats were divided into four groups randomly consisted of six rats in each group. The control group (P0) was given 2 mL water, the treatment groups (VCO-1, VCO-2, and VCO-4) were given VCO 1 ml/200 g BW, 2 ml/200 g BW, and 4 ml/200 g BW, respectively, per day using gavage spuit. The rats were trained to swim for a month, 30 min/day in the 1st week, 35 min/day in the 2nd week, 40 min/ day in the 3rd week, and 45 min/day in the 4th week. After 28 days, the rats were forced to perform the maximal activity by putting the rats in water with no exit. Blood samples were collected immediately after the maximum physical activity, and then, all rats were killed and liver tissues were collected. The malondialdehyde (MDA), glutathione peroxidase (G...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2017
Aktivitas fisik berat maupun olahraga aerobik dapat meningkatkan konsumsi oksigen dalam tubuh 10... more Aktivitas fisik berat maupun olahraga aerobik dapat meningkatkan konsumsi oksigen dalam tubuh 10-20 kali dan 100-200 kali lipat pada otot. Peningkatan penggunaan oksigen akibat peningkatan aktifitas dapat meningkatkan produksi radikal yang dapat mempengaruhi performance atlet ditandai dengan turunnya Hb. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian vitamin E terhadap kadar hemoglobin pada aktifitas fisik maksimal mahasiswa Ilmu Keolahragaan FIK Unimed.Jenis penelitian yang dilakukan adalah penelitian eksperimental semu dengan rancangan penelitian Randomized Control Group Pretest-Postest Design. Penelitian dilaksanakan di Stadion Sepakbola dan Laboratorium Fisiologi FIK UNIMED. Penelitian dilakukan selama 2 bulan dengan populasi dan sampel mahasiswa Ilmu Keolahragaan yang memenuhi kriteria. Pada penelitian ini akan diukur kadar Haemoglobin sebelum dan sesudah mengkonsumsi Vitamin E dengan dosis 400mg setelah melakukan aktifitas fisik maksimalDari hasil ana...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2019
Prevalensi obesitas dari tahun ke tahun mengalami peningkatan yang dapat membahayakan kesehatan t... more Prevalensi obesitas dari tahun ke tahun mengalami peningkatan yang dapat membahayakan kesehatan terutama penyakit cardiovascular yang ditandai dengan peningkatan Indeks Massa Tubuh (IMT) dan kadar kolesterol. Tujuan penelitian adalah untuk mengetahui pengaruh senam aerobik intensitas sedang terhadap penurunan Indeks Massa Tubuh dan kadar total kolesterol pada wanita penderita obesitas. Jenis penelitian adalah penelitian eksperimental semu dengan rancangan penelitian one group pretest postets design. Sampel penelitian berjumlah 10 orang yang sudah memenuhi kriteria. Senam aerobik dilakukan selama satu bulan, 3 kali seminggu, waktu 50 menit dengan target denyut jantung 60-70% MHR. Pengukuran IMT dan kolesterol total dilakukan sebelum dimulai program latihan dan setelah dan setelah menjalani program latihan senam aerobik. Hasil penelitian diperoleh IMT dan kadar kolesterol total pretest adalah 39,61 kg/m2 dan 191,1 mg/dl. Kadar IMT dan kadar kolesterol total postest adalah 24,81 kg/m2...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2019
Aktifitas fisik maksimal dapat mempengaruhi kesehatan dan performance atlet akibat meningkatnya p... more Aktifitas fisik maksimal dapat mempengaruhi kesehatan dan performance atlet akibat meningkatnya produksi radikal bebas di dalam tubuh. Tujuan penelitian adalah untuk mengetahui pengaruh aktifitas fisik maksimal terhadap jumlah leukosit dan hitung jenis leukosit pada Atlet Softball Putri Universitas Negeri Medan. Penelitian ini menggunakan metode quasi eksperimen dengan rancangan penelitian one group pretest posttest. Jumlah sampel berjumlah 11 orang. Pengukuran kadar leukosit dan hitung jenis leukosit dilakukan sebelum dan setelah melakukan aktifitas fisik maksimal. Hasil penelitian diperoleh rerata jumlah leukosit pretest 8,37 dan posttest sebesar 13,03; rerata jumlah neutrofil pretest 56,45 dan posttest 46,27; rerata jumlah limfosit pretest 33,27 dan posttest 42,90; rerata monosit pretest 6,45 dan posttest 7,63; rerata jumlah eusinofil pretest 3,81 dan posttest 3,18. Hasil uji-t berpasangan menunjukan bahwa aktifitas fisik maksimal dapat meningkatkan jumlah leukosit dan limfosit s...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2019
Aktifitas fisik berat dapat mengakibatkan terjadi stress oksidatif yang berdampak kepada penuruna... more Aktifitas fisik berat dapat mengakibatkan terjadi stress oksidatif yang berdampak kepada penurunan performance dan kesehatan atlet. Stres oksidatif dapat dicegah atau dikurangi dengan pemberian antioksidan. Salah satu sumber alami yang mengandung antioksidan adalah minyak buah merah (MBM). Sebagai antioksidan MBM diklaim mempunyai banyak khasiat tetapi semua efek ini masih perlu pembuktian secara ilmiah. Tujuan penelitian adalah untuk untuk melihat pengaruh pemberian MBM terhadap kadar Serum Glutamic Oxaloacetic Transaminase (SGPT) dan serum glutamate piruvat transferase serum tikus pada aktifitas fisik maksimal. Jenis penelitian yang dilakukan adalah penelitian eksperimental dengan rancangan penelitian randomized control group postest only group design. Penelitian dilakukan di Laboratorium Farmakologi Fakultas Farmasi Universitas Sumatera Utara. Penelitian menggunakan 40 ekor tikus yang dibagi menjadi empat kelompok yaitu kelompok kontrol (C); E-15; E-30 dan E-60 masing-masing d...
Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan, 2018
Aktifitas fisik dapat menyebabkan peningkatan produksi radikal bebas yang menyebabkan terjadi str... more Aktifitas fisik dapat menyebabkan peningkatan produksi radikal bebas yang menyebabkan terjadi stress oksidatif akibat jumlah radikal bebas melebihi jumlah antioksidan tubuh. Stres oksidatif dapat menyebabkan peningkatan jumlah leukosit. Jumlah leukosit perifer dapat menjadi sumber informasi untuk diagnosa dan prognosa serta gambaran kerusakan organ dan pemulihan setelah olahraga. Radikal bebas dapat dicegah atau dikurangi dengan pemberian antioksidan. Telah diketahui buah jambu biji merah mengandung antioksidan. Tujuan penelitian adalah untuk mengetahui pengaruh pemberian jus buah jambu biji merah terhadap jumlah leukosit pada aktifitas fisik maksimal. Jenis penelitian yang dilakukan adalah penelitian eksperimental dengan rancangan penelitian randomized control group pretest-postest design. Sampel penelitian adalah mahasiswa Ilmu Keolahragaan sebanyak 30 orang yang memenuhi kriteria. Selanjutnya sampel dibagi atas 3 kelompok (P1=10, P2=10, dan P3=10). Selama menjalani program latiha...
Severe physical activity can cause lipid peroxidation marked by increased levels of malondialdehy... more Severe physical activity can cause lipid peroxidation marked by increased levels of malondialdehyde (MDA) which can reduce athlete's performance and health. Lipid peroxidation can be prevented or reduced by administering antioxidants. Beets (Beta Vulgaris L) contain various types of natural antioxidants but have not been investigated for their efficacy to reduce lipid peroxidation that is triggered by physical activity. The purpose of this study was to determine the effect of beetroot juice during exercise on lipid peroxidation during maximum physical activity.This type of research is an experimental study with a randomized control group pretestposttest design research design. The study was conducted at the Unimed Stadium and the USU Faculty of Medicine Integrated Laboratory. The sample was 30 students of Sports Science who met the criteria. Pretest is done by checking MDA levels. Furthermore the sample was divided into 2 groups (P1 = 15, P2 = 15). During the training program gr...
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