Page 1. Fundamenta Informaticae 34 (1998) 1{16 1 IOS Press A Study on Partitioned Iterative Funct... more Page 1. Fundamenta Informaticae 34 (1998) 1{16 1 IOS Press A Study on Partitioned Iterative Function Systems for Image Compression Suman K. Mitra, CA Murthy and Malay K. Kundu Machine Intelligence Unit, Indian Statistical Institute, 203, BT Road, Calcutta 700035. INDIA. ...
Abstract: Location of eyes is an important visual clue for processes such as scaling and orientat... more Abstract: Location of eyes is an important visual clue for processes such as scaling and orientation correction, which are precursors to face recognition. This paper presents a robust algorithm for eye detection which makes use of edge information and distinctive features of eyes, ...
We propose a system that learns from the STARE (STructured Analysis of REtina) database and explo... more We propose a system that learns from the STARE (STructured Analysis of REtina) database and exploits the experience of ophthalmologists to assist in decision-making regarding the presence or absence of retinal diseases. The developed system automatically detects diseases given a description (a set of manifestations) of a retinal image. The manifestations in the retinal image are usually fed sequentially into
Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in resp... more Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic tetrapods possess cells that express TcR and CD4-related genes (that exist in two forms in teleost fish; termed CD4-1 and CD4-2), to date there is no unequivocal demonstration that cells equivalent to Th exist. Thus, in this study we determined whether CD4-1+ lymphocytes can express cytokines typical of Th cells following antigen specific stimulation, using the zebrafish (Danio rerio). Initially, we analyzed the CD4 locus in zebrafish and found three CD4 homologues, a CD4-1 molecule and two CD4-2 molecules. The zfCD4-1 and zfCD4-2 transcripts were detected in immune organs and were most highly expressed in lymphocytes. A polyclonal antibody to zfCD4-1 was developed and used with an antibody to ZAP70 and revealed double positive cells by immunohistochemistry, and in the Mycobacterium marinum disease model CD4-1+ cel...
Interleukin-2 (IL-2) regulates lymphocyte function by signaling through heterodimerization of the... more Interleukin-2 (IL-2) regulates lymphocyte function by signaling through heterodimerization of the IL-2Rβ and γc receptor subunits. IL-2 is of considerable therapeutic interest, but harnessing its actions in a controllable manner remains a challenge. Previously, we have engineered an IL-2 "superkine" with enhanced affinity for IL-2Rβ. Here, we describe next-generation IL-2 variants that function as "receptor signaling clamps." They retained high affinity for IL-2Rβ, inhibiting binding of endogenous IL-2, but their interaction with γc was weakened, attenuating IL-2Rβ-γc heterodimerization. These IL-2 analogs acted as partial agonists and differentially affected lymphocytes poised at distinct activation thresholds. Moreover, one variant, H9-RETR, antagonized IL-2 and IL-15 better than blocking antibodies against IL-2Rα or IL-2Rβ. Furthermore, this mutein prolonged survival in a model of graft-versus-host disease and blocked spontaneous proliferation of smoldering ad...
Abstract. Many applications like image compression requires sparse representation of image. To re... more Abstract. Many applications like image compression requires sparse representation of image. To represent the image by sparse coefficients of transform is an old age technique. Still research is going on for bet-ter sparse representation of an image. A very recent ...
Page 1. Hybrid Audio Watermarking with Spread Spectrum and Singular Value Decomposition Akankshu ... more Page 1. Hybrid Audio Watermarking with Spread Spectrum and Singular Value Decomposition Akankshu Dhawanl and Suman K. Mitra2 lUniversity of Massachusetts, Dartmouth, MA-02740, USA 2Dhirubhai Ambani Institute ...
IET International Conference on Visual Information Engineering (VIE 2006), 2006
A graphical approach for fingerprint verification. [IET Conference Publications 2006, 68 (2006)].... more A graphical approach for fingerprint verification. [IET Conference Publications 2006, 68 (2006)]. S. Jain, SK Mitra, A. Banerjee, AK Roy. Abstract. Fingerprints have established themselves as one of the best biometric for user identification. ...
The discovery of cytokines expressed by T-helper 1 (Th1), Th2, Th17 and T-regulatory (T(reg)) cel... more The discovery of cytokines expressed by T-helper 1 (Th1), Th2, Th17 and T-regulatory (T(reg)) cells has prompted speculation that these types of responses may exist in fish, arising early in vertebrate evolution. In this investigation, we cloned three zebrafish transcription factors, T-box expressed in T cells (t-bet), signal transducer and activator of transcription 6 (stat6) and fork-head box p3 (foxp3), in which two transcripts are present, that are important in the development of a number of these cell types. They were found within the zebrafish genome, using a synteny approach in the case of t-bet and foxp3. Multiple alignments of zebrafish t-bet, stat6 and foxp3 amino acids with known vertebrate homologues revealed regions of high conservation, subsequently identified to be protein domains important in the functioning of these transcription factors. The gene organizations of zebrafish t-bet and foxp3 were identical to those of the human genes, with the second foxp3 transcript ...
2012 Third International Conference on Emerging Applications of Information Technology, 2012
ABSTRACT Locality Preserving Projection (LPP) is a recently proposed approach for dimensionality ... more ABSTRACT Locality Preserving Projection (LPP) is a recently proposed approach for dimensionality reduction that preserves the neighbourhood information and is widely used for finding the intrinsic dimensionality of the data which is usually of high dimension. A new proposal called Extended LPP (ELPP) has been introduced in which a weighing scheme is designed that pays importance to the data points which are at a moderate distance, in addition to the nearest points. This helps to resolve the ambiguity occurring at the overlapping regions as well as increase the reducibility capacity. The proposal is further extended to the supervised version of LPP (SLPP) that uses the known class labels of data points to enhance the discriminating power along with inheriting the properties of ELPP. Both proposals are tested on variety of datasets leading towards significant improvement in the results.
Reinforcement of polymer matrix by various particulate fillers is an integral part of polymer pro... more Reinforcement of polymer matrix by various particulate fillers is an integral part of polymer processing and subsequent end product manufacturing. Although reinforcement refers to overall improvement in various physical and failure properties in the filled vulcanizates, it also considerably ...
Page 1. Fundamenta Informaticae 34 (1998) 1{16 1 IOS Press A Study on Partitioned Iterative Funct... more Page 1. Fundamenta Informaticae 34 (1998) 1{16 1 IOS Press A Study on Partitioned Iterative Function Systems for Image Compression Suman K. Mitra, CA Murthy and Malay K. Kundu Machine Intelligence Unit, Indian Statistical Institute, 203, BT Road, Calcutta 700035. INDIA. ...
Abstract: Location of eyes is an important visual clue for processes such as scaling and orientat... more Abstract: Location of eyes is an important visual clue for processes such as scaling and orientation correction, which are precursors to face recognition. This paper presents a robust algorithm for eye detection which makes use of edge information and distinctive features of eyes, ...
We propose a system that learns from the STARE (STructured Analysis of REtina) database and explo... more We propose a system that learns from the STARE (STructured Analysis of REtina) database and exploits the experience of ophthalmologists to assist in decision-making regarding the presence or absence of retinal diseases. The developed system automatically detects diseases given a description (a set of manifestations) of a retinal image. The manifestations in the retinal image are usually fed sequentially into
Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in resp... more Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic tetrapods possess cells that express TcR and CD4-related genes (that exist in two forms in teleost fish; termed CD4-1 and CD4-2), to date there is no unequivocal demonstration that cells equivalent to Th exist. Thus, in this study we determined whether CD4-1+ lymphocytes can express cytokines typical of Th cells following antigen specific stimulation, using the zebrafish (Danio rerio). Initially, we analyzed the CD4 locus in zebrafish and found three CD4 homologues, a CD4-1 molecule and two CD4-2 molecules. The zfCD4-1 and zfCD4-2 transcripts were detected in immune organs and were most highly expressed in lymphocytes. A polyclonal antibody to zfCD4-1 was developed and used with an antibody to ZAP70 and revealed double positive cells by immunohistochemistry, and in the Mycobacterium marinum disease model CD4-1+ cel...
Interleukin-2 (IL-2) regulates lymphocyte function by signaling through heterodimerization of the... more Interleukin-2 (IL-2) regulates lymphocyte function by signaling through heterodimerization of the IL-2Rβ and γc receptor subunits. IL-2 is of considerable therapeutic interest, but harnessing its actions in a controllable manner remains a challenge. Previously, we have engineered an IL-2 "superkine" with enhanced affinity for IL-2Rβ. Here, we describe next-generation IL-2 variants that function as "receptor signaling clamps." They retained high affinity for IL-2Rβ, inhibiting binding of endogenous IL-2, but their interaction with γc was weakened, attenuating IL-2Rβ-γc heterodimerization. These IL-2 analogs acted as partial agonists and differentially affected lymphocytes poised at distinct activation thresholds. Moreover, one variant, H9-RETR, antagonized IL-2 and IL-15 better than blocking antibodies against IL-2Rα or IL-2Rβ. Furthermore, this mutein prolonged survival in a model of graft-versus-host disease and blocked spontaneous proliferation of smoldering ad...
Abstract. Many applications like image compression requires sparse representation of image. To re... more Abstract. Many applications like image compression requires sparse representation of image. To represent the image by sparse coefficients of transform is an old age technique. Still research is going on for bet-ter sparse representation of an image. A very recent ...
Page 1. Hybrid Audio Watermarking with Spread Spectrum and Singular Value Decomposition Akankshu ... more Page 1. Hybrid Audio Watermarking with Spread Spectrum and Singular Value Decomposition Akankshu Dhawanl and Suman K. Mitra2 lUniversity of Massachusetts, Dartmouth, MA-02740, USA 2Dhirubhai Ambani Institute ...
IET International Conference on Visual Information Engineering (VIE 2006), 2006
A graphical approach for fingerprint verification. [IET Conference Publications 2006, 68 (2006)].... more A graphical approach for fingerprint verification. [IET Conference Publications 2006, 68 (2006)]. S. Jain, SK Mitra, A. Banerjee, AK Roy. Abstract. Fingerprints have established themselves as one of the best biometric for user identification. ...
The discovery of cytokines expressed by T-helper 1 (Th1), Th2, Th17 and T-regulatory (T(reg)) cel... more The discovery of cytokines expressed by T-helper 1 (Th1), Th2, Th17 and T-regulatory (T(reg)) cells has prompted speculation that these types of responses may exist in fish, arising early in vertebrate evolution. In this investigation, we cloned three zebrafish transcription factors, T-box expressed in T cells (t-bet), signal transducer and activator of transcription 6 (stat6) and fork-head box p3 (foxp3), in which two transcripts are present, that are important in the development of a number of these cell types. They were found within the zebrafish genome, using a synteny approach in the case of t-bet and foxp3. Multiple alignments of zebrafish t-bet, stat6 and foxp3 amino acids with known vertebrate homologues revealed regions of high conservation, subsequently identified to be protein domains important in the functioning of these transcription factors. The gene organizations of zebrafish t-bet and foxp3 were identical to those of the human genes, with the second foxp3 transcript ...
2012 Third International Conference on Emerging Applications of Information Technology, 2012
ABSTRACT Locality Preserving Projection (LPP) is a recently proposed approach for dimensionality ... more ABSTRACT Locality Preserving Projection (LPP) is a recently proposed approach for dimensionality reduction that preserves the neighbourhood information and is widely used for finding the intrinsic dimensionality of the data which is usually of high dimension. A new proposal called Extended LPP (ELPP) has been introduced in which a weighing scheme is designed that pays importance to the data points which are at a moderate distance, in addition to the nearest points. This helps to resolve the ambiguity occurring at the overlapping regions as well as increase the reducibility capacity. The proposal is further extended to the supervised version of LPP (SLPP) that uses the known class labels of data points to enhance the discriminating power along with inheriting the properties of ELPP. Both proposals are tested on variety of datasets leading towards significant improvement in the results.
Reinforcement of polymer matrix by various particulate fillers is an integral part of polymer pro... more Reinforcement of polymer matrix by various particulate fillers is an integral part of polymer processing and subsequent end product manufacturing. Although reinforcement refers to overall improvement in various physical and failure properties in the filled vulcanizates, it also considerably ...
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