International Journal of Health & Medical Sciences, 2022
The main goal of our study was to identify the activity of cardiac dysfunction based on the analy... more The main goal of our study was to identify the activity of cardiac dysfunction based on the analysis of the main cardiological methods of research, such as ECG, echocardiography, 24-hour ECG monitoring in conjunction with laboratory parameters in patients with coronary artery disease (CAD) who underwent mild and moderate COVID-19, without signs of residual effects of lung tissue damage (fibrotization). 52 patients with coronary artery disease were examined, which were divided into 2 groups depending on the past infection in history: 1 group without COVID-19 in history (n=26) (based on history and results of SARS-CoV-2 antibody titer), 2 a group with a history of COVID-19 (n=26), confirmed by relevant documents (tests), but without oxygen therapy and steroids, in order to avoid the influence of a serious illness and drug exposure. Conclusions: dynamic monitoring of hemostasis parameters after the hospital stage in patients with CAD should be carried out in order to prevent adverse cardiovascular outcomes, even with a history of moderate and mild coronavirus infection. One of the aspects of therapeutic rehabilitation in the post-COVID period in patients with IHD is the use of vitamin D preparations.
The lung tissue contains various hemostatic system elements, which can be released from the lungs... more The lung tissue contains various hemostatic system elements, which can be released from the lungs, both under physiological and pathological conditions. The COVID-19 pandemic has led to an increase in the number of patients with acute respiratory distress syndrome (ARDS) in intensive care units worldwide. When the lungs are damaged, coagulation disorders are mediated by tissue factor (TF) - factor VIIa (F VIIa), and inhibition of this pathway completely eliminates intrapulmonary fibrin deposition. A tissue factor pathway inhibitor TFPI also contributes to pulmonary coagulationdisturbance in ARDS. Pulmonary coagulationdisturbance caused by pneumonia can worsen the damage to the lungs and thus contribute to the progression of the disease. Cytokines are the main linking factors between inflammation and changes in blood clotting and fibrinolysis. The sources of proinflammatory cytokines in the lungs are probably alveolar macrophages. The activation of alveolar macrophages occurs through...
The study of the processes of adaptation and characteristics of energy metabolism in patients wit... more The study of the processes of adaptation and characteristics of energy metabolism in patients with diabetes mellitus (DM) type 2 can serve as a basis for determining their role in the pathogenesis of this disease and contribute to the development of new methods of treatment and prevention. The aim of the study was to determine the level of adaptive capacity and state of the energy metabolism in patients with type 2 diabetes. Materials and Methods. The study involved 27 patients with DM type 2 (mean age — 56.9 years) and disease duration from 1 year to 20 years. Group of 15 apparently healthy volunteers, similar to the main group by age and sex, served as control one. Results. It is found that patients with DM type 2 had a reduction in adaptive abilities, which is based on violation of the energy metabolism of the body. In DM decompensation, the reduction of organism adaptation was more significant. Conclusions. Patients with DM type 2 were characterized by reduced level of adenosine...
The study of the processes of adaptation and characteristics of energy metabolism in patients wit... more The study of the processes of adaptation and characteristics of energy metabolism in patients with diabetes mellitus (DM) type 2 can serve as a basis for determining their role in the pathogenesis of this disease and contribute to the development of new methods of treatment and prevention. The aim of the study was to determine the level of adaptive capacity and state of the energy metabolism in patients with type 2 diabetes. Materials and Methods. The study involved 27 patients with DM type 2 (mean age — 56.9 years) and disease duration from 1 year to 20 years. Group of 15 apparently healthy volunteers, similar to the main group by age and sex, served as control one. Results. It is found that patients with DM type 2 had a reduction in adaptive abilities, which is based on violation of the energy metabolism of the body. In DM decompensation, the reduction of organism adaptation was more significant. Conclusions. Patients with DM type 2 were characterized by reduced level of adenosine...
Four hundred sixty women of reproductive age (15-49 years old) were examined. Among them, blood p... more Four hundred sixty women of reproductive age (15-49 years old) were examined. Among them, blood pressure and body weight were assessed depending on the number of pregnancies and births in the anamnesis. At the time of the examination, these women were not pregnant. Bodyweight was studied according to the height-weight index (Quetelet index). Cases of termination of pregnancy for various reasons and the birth of a stillborn child were not taken into account. The study did not include cases of severe arterial hypertension (AH), grade 2 and 3 obesity, decompensated diabetes mellitus, and heart failure. It was found that the number of pregnancies and births of more than two is ssociated with an increase in blood pressure and body weight. Therefore, it seems appropriate to carry out preventive work in relation to the possible increase in blood pressure and body weight among this category of women. At the same time, the authors draw attention to the fact that a single-factor analysis was carried out and did not take into account such factors as the intervals between pregnancies, the presence of a number of concomitant diseases, as well as ranking by age. Therefore, the results obtained can only reflect the general situation. Keywords: women, pregnancy, arterial hypertension, overweight, obesity, risk factors, prevention.
COMPARATIVE ASSESSMENT OF THE PREVALENCE OF THE MAIN COMPONENTS OF THE METABOLIC SYNDROME IN DIFFERENT AGE GROUP, Mar 30, 2021
1193 men aged 20-69 years from the unorganized population were examined. Among them, the frequenc... more 1193 men aged 20-69 years from the unorganized population were examined. Among them, the frequency of occurrence of the main components of the metabolic syndrome (MetS) was studied: arterial hypertension, obesity and overweight, impaired glucose tolerance (IGT), and hyperlipidemia. It was found that age makes a significant contribution to the increase in MetS components. At the same time, as the age increases, the number of MetS components also increases. The decrease in the frequency of MetS components at the age of 60-69 years may be associated with a more intensive dropout of persons with c from the population due to mortality. At a young age, people without or with a small number of MetS components are most often found. As the age increases, there is an increase in MetS components and, above all, such components as AH and IGT. Keywords: metabolic syndrome, age, aging, impaired glucose tolerance, arterial hypertension, overweight, obesity, dyslipidemia.
Annals of the Romanian Society for Cell Biology, 2021
In a specialized hospital for the treatment of 63 patients with coronavirus disease, moderate and... more In a specialized hospital for the treatment of 63 patients with coronavirus disease, moderate and severe COVID-19 were monitored. These patients were diagnosed with coronary heart disease or arterial hypertension prior to COVID-19. According to computed tomography data, it was found that adherence to hypercoagulation and the severity of the clinical course of coronavirus disease in this category of patients does not depend on the proportion of lung tissue damage. Senile age and an increase in body mass index> 30 kg / m2 were found to be significant factors aggravating the processes of hypercoagulation.
One hundred thirty-three patients with components of metabolic syndrome aged from 40 to 60 years ... more One hundred thirty-three patients with components of metabolic syndrome aged from 40 to 60 years were examined. To identify MS and its main components, the diagnostic criteria of MS recommended by the International Diabetes Federation (IDF,2005). Taking into account that the study provided for a comparative assessment of the relationship of disorders of the sympathoadrenal and vagoinsular phases of the glycemic curve with asymptomatic hyperuricemia, the level of glycemia was also determined one an hour after glucose loading (> 8.8 mmol/l). Uric acid (MC) was determined in serum. Blood uric acid levels >7 mg/DL were interpreted as hyperuricemia. Diagnosis of coronary heart disease was carried out based on a survey, ECG, and the results of previous examinations. The ECG was recorded at rest in 12 standard leads and analyzed according to the Minnesota code criteria. The Association of uric acid with bodyweight and glycemic indices was established. To a greater extent, asymptomatic hyperuricemia is associated with glycemic levels 2 hours after glucose loading. It is assumed that the relationship of uric acid level with body weight may be due to the criteria for detection of both overweight and obesity, and the criteria of hyperuricemia. The risk group for asymptomatic hyperuricemia and CHD should include persons who are not informed about the presence or absence of CHD.
Обследовано 1335 человек, представляющих собой репрезентативную выборку из мужского
населения в в... more Обследовано 1335 человек, представляющих собой репрезентативную выборку из мужского населения в возрасте 20-69 лет. В течение 12 лет среди них проводился регистр смертности. Показатели смертности изучались относительно общего числа умерших в рассматриваемых группах. Показано, что наличие различных компонентов метаболического синдрома (МС) сопряжено с повышенным риском общей смертности. Профиль риска общей смертности в различные возрастные периоды неоднозначен. В молодом возрасте наибольший риск смертности связан с курением и артериальной гипертензией. В последующие годы возрастает значимость артериальной гипертензии (АГ) и нарушенной толерантности к глюкозе (НТГ). Среди лиц пожилого возраста наиболее важными факторами риска общей смертности являются АГ, НТГ и избыточная масса тела. После 30 лет отмечается возрастание значимости НТГ. Этот компонент МС во многом определяет степень риска общей смертности. Его значимость существенно увеличивается при сочетании с другими компонентами МС и курением. Вместе с тем, одним из ключевых моментов своевременной диагностики и успешного лечения является отношение больного к своей болезни. Это отношение и оценка пациентом своего здоровья в известной мере определяет конечный результат лечения. Ключевые слова: смертность, метаболический синдром, нарушение толерантности к глюкозе, хроническая болезнь почек, ожирение, диабет
One thousand three hundred thirty-five men representing a representative sample of the man’s popu... more One thousand three hundred thirty-five men representing a representative sample of the man’s population in the age of 20-69 years are surveyed. Within 12 years among them, the register of mortality was carried out. The parameters of death were studied concerning the general number died in examined groups. It is shown that the presence of various components of metabolic syndrome (MS) conjugates to the increased risk of total mortality. The structure of the risk of overall death in the different age periods is ambiguous. At a young age, the highest risk of dying is connected to smoking and arterial hypertension (AG). The next years the importance of arterial hypertension and glucose intolerance (GI) grows. Among the persons of elderly age, the most critical risk factors of total mortality are AG, GI, and increased mass of a body (IMB). After 30 years, ascending the importance of the GI is marked. This component MS, in many respects, determines a degree of risk of total mortality. Its essence is essentially enlarged at a combination of other parts of MS and smoking.
Артериальная гипертензия (АГ) остаётся одной из наиболее важных проблем современной науки и практ... more Артериальная гипертензия (АГ) остаётся одной из наиболее важных проблем современной науки и практики. Для успешной борьбы с этим заболеванием органам здравоохранения необходимо располагать сведениями о распространённости АГ, а также значимости различных модифицируемых и не модифицируемых факторов риса. К числу не модифицируемых факторов риска относится возраст. В настоящем исследовании дана оценка распространённости АГ среди неорганизованного мужского населения в возрасте 20-69 лет. В работе применены популяционные методы исследования, рекомендованные ВОЗ для эпидемиологических исследований. Показано увеличение частоты АГ с возрастом, а также особенности частоты различных градаций АД в отдельных возрастных группах.
Journal of Multidisciplinary Engineering Science and Technology, 2019
The article presents the results of the study of the frequency of individual clinical symptoms ch... more The article presents the results of the study of the frequency of individual clinical symptoms characteristic of diabetes mellitus in persons with prediabetes. It was found that symptoms such as dry mouth, thirst, increased fluid intake, itching of the skin, various sensations characteristic of angiopathy, are often found in patients with prediabetes. The frequency and severity of these symptoms were associated with blood glucose levels. The authors came to the conclusion that in mass surveys of the population, at the first stage, a questionnaire should be used to identify clinical manifestations of diabetes mellitus. As a result of the survey, a high-risk group can be identified. In the future, this group should study the level of blood glucose, glycated hemoglobin, and other studies. Based on the results obtained, targeted prevention and treatment of prediabetes should be carried out.
International Journal of Health & Medical Sciences, 2022
The main goal of our study was to identify the activity of cardiac dysfunction based on the analy... more The main goal of our study was to identify the activity of cardiac dysfunction based on the analysis of the main cardiological methods of research, such as ECG, echocardiography, 24-hour ECG monitoring in conjunction with laboratory parameters in patients with coronary artery disease (CAD) who underwent mild and moderate COVID-19, without signs of residual effects of lung tissue damage (fibrotization). 52 patients with coronary artery disease were examined, which were divided into 2 groups depending on the past infection in history: 1 group without COVID-19 in history (n=26) (based on history and results of SARS-CoV-2 antibody titer), 2 a group with a history of COVID-19 (n=26), confirmed by relevant documents (tests), but without oxygen therapy and steroids, in order to avoid the influence of a serious illness and drug exposure. Conclusions: dynamic monitoring of hemostasis parameters after the hospital stage in patients with CAD should be carried out in order to prevent adverse cardiovascular outcomes, even with a history of moderate and mild coronavirus infection. One of the aspects of therapeutic rehabilitation in the post-COVID period in patients with IHD is the use of vitamin D preparations.
The lung tissue contains various hemostatic system elements, which can be released from the lungs... more The lung tissue contains various hemostatic system elements, which can be released from the lungs, both under physiological and pathological conditions. The COVID-19 pandemic has led to an increase in the number of patients with acute respiratory distress syndrome (ARDS) in intensive care units worldwide. When the lungs are damaged, coagulation disorders are mediated by tissue factor (TF) - factor VIIa (F VIIa), and inhibition of this pathway completely eliminates intrapulmonary fibrin deposition. A tissue factor pathway inhibitor TFPI also contributes to pulmonary coagulationdisturbance in ARDS. Pulmonary coagulationdisturbance caused by pneumonia can worsen the damage to the lungs and thus contribute to the progression of the disease. Cytokines are the main linking factors between inflammation and changes in blood clotting and fibrinolysis. The sources of proinflammatory cytokines in the lungs are probably alveolar macrophages. The activation of alveolar macrophages occurs through...
The study of the processes of adaptation and characteristics of energy metabolism in patients wit... more The study of the processes of adaptation and characteristics of energy metabolism in patients with diabetes mellitus (DM) type 2 can serve as a basis for determining their role in the pathogenesis of this disease and contribute to the development of new methods of treatment and prevention. The aim of the study was to determine the level of adaptive capacity and state of the energy metabolism in patients with type 2 diabetes. Materials and Methods. The study involved 27 patients with DM type 2 (mean age — 56.9 years) and disease duration from 1 year to 20 years. Group of 15 apparently healthy volunteers, similar to the main group by age and sex, served as control one. Results. It is found that patients with DM type 2 had a reduction in adaptive abilities, which is based on violation of the energy metabolism of the body. In DM decompensation, the reduction of organism adaptation was more significant. Conclusions. Patients with DM type 2 were characterized by reduced level of adenosine...
The study of the processes of adaptation and characteristics of energy metabolism in patients wit... more The study of the processes of adaptation and characteristics of energy metabolism in patients with diabetes mellitus (DM) type 2 can serve as a basis for determining their role in the pathogenesis of this disease and contribute to the development of new methods of treatment and prevention. The aim of the study was to determine the level of adaptive capacity and state of the energy metabolism in patients with type 2 diabetes. Materials and Methods. The study involved 27 patients with DM type 2 (mean age — 56.9 years) and disease duration from 1 year to 20 years. Group of 15 apparently healthy volunteers, similar to the main group by age and sex, served as control one. Results. It is found that patients with DM type 2 had a reduction in adaptive abilities, which is based on violation of the energy metabolism of the body. In DM decompensation, the reduction of organism adaptation was more significant. Conclusions. Patients with DM type 2 were characterized by reduced level of adenosine...
Four hundred sixty women of reproductive age (15-49 years old) were examined. Among them, blood p... more Four hundred sixty women of reproductive age (15-49 years old) were examined. Among them, blood pressure and body weight were assessed depending on the number of pregnancies and births in the anamnesis. At the time of the examination, these women were not pregnant. Bodyweight was studied according to the height-weight index (Quetelet index). Cases of termination of pregnancy for various reasons and the birth of a stillborn child were not taken into account. The study did not include cases of severe arterial hypertension (AH), grade 2 and 3 obesity, decompensated diabetes mellitus, and heart failure. It was found that the number of pregnancies and births of more than two is ssociated with an increase in blood pressure and body weight. Therefore, it seems appropriate to carry out preventive work in relation to the possible increase in blood pressure and body weight among this category of women. At the same time, the authors draw attention to the fact that a single-factor analysis was carried out and did not take into account such factors as the intervals between pregnancies, the presence of a number of concomitant diseases, as well as ranking by age. Therefore, the results obtained can only reflect the general situation. Keywords: women, pregnancy, arterial hypertension, overweight, obesity, risk factors, prevention.
COMPARATIVE ASSESSMENT OF THE PREVALENCE OF THE MAIN COMPONENTS OF THE METABOLIC SYNDROME IN DIFFERENT AGE GROUP, Mar 30, 2021
1193 men aged 20-69 years from the unorganized population were examined. Among them, the frequenc... more 1193 men aged 20-69 years from the unorganized population were examined. Among them, the frequency of occurrence of the main components of the metabolic syndrome (MetS) was studied: arterial hypertension, obesity and overweight, impaired glucose tolerance (IGT), and hyperlipidemia. It was found that age makes a significant contribution to the increase in MetS components. At the same time, as the age increases, the number of MetS components also increases. The decrease in the frequency of MetS components at the age of 60-69 years may be associated with a more intensive dropout of persons with c from the population due to mortality. At a young age, people without or with a small number of MetS components are most often found. As the age increases, there is an increase in MetS components and, above all, such components as AH and IGT. Keywords: metabolic syndrome, age, aging, impaired glucose tolerance, arterial hypertension, overweight, obesity, dyslipidemia.
Annals of the Romanian Society for Cell Biology, 2021
In a specialized hospital for the treatment of 63 patients with coronavirus disease, moderate and... more In a specialized hospital for the treatment of 63 patients with coronavirus disease, moderate and severe COVID-19 were monitored. These patients were diagnosed with coronary heart disease or arterial hypertension prior to COVID-19. According to computed tomography data, it was found that adherence to hypercoagulation and the severity of the clinical course of coronavirus disease in this category of patients does not depend on the proportion of lung tissue damage. Senile age and an increase in body mass index> 30 kg / m2 were found to be significant factors aggravating the processes of hypercoagulation.
One hundred thirty-three patients with components of metabolic syndrome aged from 40 to 60 years ... more One hundred thirty-three patients with components of metabolic syndrome aged from 40 to 60 years were examined. To identify MS and its main components, the diagnostic criteria of MS recommended by the International Diabetes Federation (IDF,2005). Taking into account that the study provided for a comparative assessment of the relationship of disorders of the sympathoadrenal and vagoinsular phases of the glycemic curve with asymptomatic hyperuricemia, the level of glycemia was also determined one an hour after glucose loading (> 8.8 mmol/l). Uric acid (MC) was determined in serum. Blood uric acid levels >7 mg/DL were interpreted as hyperuricemia. Diagnosis of coronary heart disease was carried out based on a survey, ECG, and the results of previous examinations. The ECG was recorded at rest in 12 standard leads and analyzed according to the Minnesota code criteria. The Association of uric acid with bodyweight and glycemic indices was established. To a greater extent, asymptomatic hyperuricemia is associated with glycemic levels 2 hours after glucose loading. It is assumed that the relationship of uric acid level with body weight may be due to the criteria for detection of both overweight and obesity, and the criteria of hyperuricemia. The risk group for asymptomatic hyperuricemia and CHD should include persons who are not informed about the presence or absence of CHD.
Обследовано 1335 человек, представляющих собой репрезентативную выборку из мужского
населения в в... more Обследовано 1335 человек, представляющих собой репрезентативную выборку из мужского населения в возрасте 20-69 лет. В течение 12 лет среди них проводился регистр смертности. Показатели смертности изучались относительно общего числа умерших в рассматриваемых группах. Показано, что наличие различных компонентов метаболического синдрома (МС) сопряжено с повышенным риском общей смертности. Профиль риска общей смертности в различные возрастные периоды неоднозначен. В молодом возрасте наибольший риск смертности связан с курением и артериальной гипертензией. В последующие годы возрастает значимость артериальной гипертензии (АГ) и нарушенной толерантности к глюкозе (НТГ). Среди лиц пожилого возраста наиболее важными факторами риска общей смертности являются АГ, НТГ и избыточная масса тела. После 30 лет отмечается возрастание значимости НТГ. Этот компонент МС во многом определяет степень риска общей смертности. Его значимость существенно увеличивается при сочетании с другими компонентами МС и курением. Вместе с тем, одним из ключевых моментов своевременной диагностики и успешного лечения является отношение больного к своей болезни. Это отношение и оценка пациентом своего здоровья в известной мере определяет конечный результат лечения. Ключевые слова: смертность, метаболический синдром, нарушение толерантности к глюкозе, хроническая болезнь почек, ожирение, диабет
One thousand three hundred thirty-five men representing a representative sample of the man’s popu... more One thousand three hundred thirty-five men representing a representative sample of the man’s population in the age of 20-69 years are surveyed. Within 12 years among them, the register of mortality was carried out. The parameters of death were studied concerning the general number died in examined groups. It is shown that the presence of various components of metabolic syndrome (MS) conjugates to the increased risk of total mortality. The structure of the risk of overall death in the different age periods is ambiguous. At a young age, the highest risk of dying is connected to smoking and arterial hypertension (AG). The next years the importance of arterial hypertension and glucose intolerance (GI) grows. Among the persons of elderly age, the most critical risk factors of total mortality are AG, GI, and increased mass of a body (IMB). After 30 years, ascending the importance of the GI is marked. This component MS, in many respects, determines a degree of risk of total mortality. Its essence is essentially enlarged at a combination of other parts of MS and smoking.
Артериальная гипертензия (АГ) остаётся одной из наиболее важных проблем современной науки и практ... more Артериальная гипертензия (АГ) остаётся одной из наиболее важных проблем современной науки и практики. Для успешной борьбы с этим заболеванием органам здравоохранения необходимо располагать сведениями о распространённости АГ, а также значимости различных модифицируемых и не модифицируемых факторов риса. К числу не модифицируемых факторов риска относится возраст. В настоящем исследовании дана оценка распространённости АГ среди неорганизованного мужского населения в возрасте 20-69 лет. В работе применены популяционные методы исследования, рекомендованные ВОЗ для эпидемиологических исследований. Показано увеличение частоты АГ с возрастом, а также особенности частоты различных градаций АД в отдельных возрастных группах.
Journal of Multidisciplinary Engineering Science and Technology, 2019
The article presents the results of the study of the frequency of individual clinical symptoms ch... more The article presents the results of the study of the frequency of individual clinical symptoms characteristic of diabetes mellitus in persons with prediabetes. It was found that symptoms such as dry mouth, thirst, increased fluid intake, itching of the skin, various sensations characteristic of angiopathy, are often found in patients with prediabetes. The frequency and severity of these symptoms were associated with blood glucose levels. The authors came to the conclusion that in mass surveys of the population, at the first stage, a questionnaire should be used to identify clinical manifestations of diabetes mellitus. As a result of the survey, a high-risk group can be identified. In the future, this group should study the level of blood glucose, glycated hemoglobin, and other studies. Based on the results obtained, targeted prevention and treatment of prediabetes should be carried out.
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Papers by Ulugbek Kayumov
It was found that the number of pregnancies and births of more than two is ssociated with an increase in blood pressure and body weight. Therefore, it seems appropriate to carry out preventive work in relation to the possible increase in blood pressure and body weight among this category of women. At the same time, the authors draw attention to the fact that a single-factor analysis was carried out and did not take into account such factors as the intervals between pregnancies, the presence of a number of concomitant diseases, as well as ranking by age. Therefore, the results obtained can only reflect the general situation.
Keywords: women, pregnancy, arterial hypertension, overweight, obesity, risk factors,
prevention.
The decrease in the frequency of MetS components at the age of 60-69 years may be associated with a more intensive dropout of persons with c from the population due to mortality. At a young age, people without or with a small number of MetS components are most often found. As the age increases, there is an increase in MetS components and, above all, such components as AH and IGT.
Keywords: metabolic syndrome, age, aging, impaired glucose tolerance, arterial hypertension, overweight, obesity, dyslipidemia.
The Association of uric acid with bodyweight and glycemic indices was established. To a greater extent, asymptomatic hyperuricemia is associated with glycemic levels 2 hours after glucose loading. It is assumed that the relationship of uric acid level with body weight may be due to the criteria for detection of both overweight and obesity, and the criteria of hyperuricemia. The risk group for asymptomatic hyperuricemia and CHD should include persons who are not informed about the presence or absence of CHD.
населения в возрасте 20-69 лет. В течение 12 лет среди них проводился регистр смертности.
Показатели смертности изучались относительно общего числа умерших в рассматриваемых
группах. Показано, что наличие различных компонентов метаболического синдрома (МС)
сопряжено с повышенным риском общей смертности. Профиль риска общей смертности
в различные возрастные периоды неоднозначен. В молодом возрасте наибольший риск
смертности связан с курением и артериальной гипертензией. В последующие годы возрастает
значимость артериальной гипертензии (АГ) и нарушенной толерантности к глюкозе (НТГ).
Среди лиц пожилого возраста наиболее важными факторами риска общей смертности являются
АГ, НТГ и избыточная масса тела. После 30 лет отмечается возрастание значимости НТГ.
Этот компонент МС во многом определяет степень риска общей смертности. Его значимость
существенно увеличивается при сочетании с другими компонентами МС и курением.
Вместе с тем, одним из ключевых моментов своевременной диагностики и успешного
лечения является отношение больного к своей болезни. Это отношение и оценка пациентом
своего здоровья в известной мере определяет конечный результат лечения.
Ключевые слова: смертность, метаболический синдром, нарушение толерантности к
глюкозе, хроническая болезнь почек, ожирение, диабет
surveyed. Within 12 years among them, the register of mortality was carried out. The parameters
of death were studied concerning the general number died in examined groups. It is shown that the
presence of various components of metabolic syndrome (MS) conjugates to the increased risk of total mortality. The structure of the risk of overall death in the different age periods is ambiguous. At
a young age, the highest risk of dying is connected to smoking and arterial hypertension (AG). The
next years the importance of arterial hypertension and glucose intolerance (GI) grows. Among the
persons of elderly age, the most critical risk factors of total mortality are AG, GI, and increased
mass of a body (IMB). After 30 years, ascending the importance of the GI is marked. This component
MS, in many respects, determines a degree of risk of total mortality. Its essence is essentially
enlarged at a combination of other parts of MS and smoking.
Ключевые слова: артериальная гипертензия, возраст, распространённость.
It was found that the number of pregnancies and births of more than two is ssociated with an increase in blood pressure and body weight. Therefore, it seems appropriate to carry out preventive work in relation to the possible increase in blood pressure and body weight among this category of women. At the same time, the authors draw attention to the fact that a single-factor analysis was carried out and did not take into account such factors as the intervals between pregnancies, the presence of a number of concomitant diseases, as well as ranking by age. Therefore, the results obtained can only reflect the general situation.
Keywords: women, pregnancy, arterial hypertension, overweight, obesity, risk factors,
prevention.
The decrease in the frequency of MetS components at the age of 60-69 years may be associated with a more intensive dropout of persons with c from the population due to mortality. At a young age, people without or with a small number of MetS components are most often found. As the age increases, there is an increase in MetS components and, above all, such components as AH and IGT.
Keywords: metabolic syndrome, age, aging, impaired glucose tolerance, arterial hypertension, overweight, obesity, dyslipidemia.
The Association of uric acid with bodyweight and glycemic indices was established. To a greater extent, asymptomatic hyperuricemia is associated with glycemic levels 2 hours after glucose loading. It is assumed that the relationship of uric acid level with body weight may be due to the criteria for detection of both overweight and obesity, and the criteria of hyperuricemia. The risk group for asymptomatic hyperuricemia and CHD should include persons who are not informed about the presence or absence of CHD.
населения в возрасте 20-69 лет. В течение 12 лет среди них проводился регистр смертности.
Показатели смертности изучались относительно общего числа умерших в рассматриваемых
группах. Показано, что наличие различных компонентов метаболического синдрома (МС)
сопряжено с повышенным риском общей смертности. Профиль риска общей смертности
в различные возрастные периоды неоднозначен. В молодом возрасте наибольший риск
смертности связан с курением и артериальной гипертензией. В последующие годы возрастает
значимость артериальной гипертензии (АГ) и нарушенной толерантности к глюкозе (НТГ).
Среди лиц пожилого возраста наиболее важными факторами риска общей смертности являются
АГ, НТГ и избыточная масса тела. После 30 лет отмечается возрастание значимости НТГ.
Этот компонент МС во многом определяет степень риска общей смертности. Его значимость
существенно увеличивается при сочетании с другими компонентами МС и курением.
Вместе с тем, одним из ключевых моментов своевременной диагностики и успешного
лечения является отношение больного к своей болезни. Это отношение и оценка пациентом
своего здоровья в известной мере определяет конечный результат лечения.
Ключевые слова: смертность, метаболический синдром, нарушение толерантности к
глюкозе, хроническая болезнь почек, ожирение, диабет
surveyed. Within 12 years among them, the register of mortality was carried out. The parameters
of death were studied concerning the general number died in examined groups. It is shown that the
presence of various components of metabolic syndrome (MS) conjugates to the increased risk of total mortality. The structure of the risk of overall death in the different age periods is ambiguous. At
a young age, the highest risk of dying is connected to smoking and arterial hypertension (AG). The
next years the importance of arterial hypertension and glucose intolerance (GI) grows. Among the
persons of elderly age, the most critical risk factors of total mortality are AG, GI, and increased
mass of a body (IMB). After 30 years, ascending the importance of the GI is marked. This component
MS, in many respects, determines a degree of risk of total mortality. Its essence is essentially
enlarged at a combination of other parts of MS and smoking.
Ключевые слова: артериальная гипертензия, возраст, распространённость.