One of the unresolved questions related to the mechanism of action of light negative air ions (re... more One of the unresolved questions related to the mechanism of action of light negative air ions (reactive oxygen species) produced by air ionizers upon humans and animals is transmission of these short-living chemical species upon long distances from the place of their origin. We discovered the phenomenon which may probably resolve this problem. When a thin layer of water hydrating a hygroscopic surface absorbs rare UV-photons capable to split water molecules a flash of photon emission in UV- and visible regions of spectrum is observed. This flash (or oxygen-dependent oxidative processes underlying it) initiate reactions accompanied with generation of electronic excitation in the air contacting water film. Excitation propagates through the air at macroscopic distances, and the level of propagating excitation increases with elevation of air humidity. When air humidity exceeds 50% air excitation gains oscillatory-wave character. This phenomenon may endow into the mechanism of action of ...
After much research in the field of biological oxidation, two main concepts of the mechanism of e... more After much research in the field of biological oxidation, two main concepts of the mechanism of energy gain were consecutively proposed--the concept of direct oxygen activation (analogous to combustion), and the concept of activation of hydrogen followed by gradual energy release (analogous to putrefaction). The latter concept currently dominates. According to it, practically all the energy required in life is gained initially in the form of ATP; the latter being synthesized mostly due to the classical oxidative phosphorylation process. Direct activation of oxygen is considered to be a secondary pathway in its utilization, unrelated to bioenergetics. Besides, this pathway seems to be risky, since reactive oxygen species (ROS) are produced on account of it. However, evidence has been accumulated that a considerable part of all oxygen consumption undergoes direct activation; and this share increases with energy demand. Recent data also argues that ROS are indispensable for regulating ...
Monitoring of spontaneous and luminophore amplified photon emission (PE) from non-diluted human b... more Monitoring of spontaneous and luminophore amplified photon emission (PE) from non-diluted human blood under resting conditions and artificially induced immune reaction revealed that blood is a continuous source of biophotons indicating that it persists in electronically excited state. This state is pumped through generation of electron excitation produced in reactive oxygen species (ROS) reactions. Excited state of blood and of neutrophil suspensions (primary sources of ROS in blood) is an oscillatory one suggesting of interaction between individual sources of electron excitation. Excited state of blood is extremely sensitive to the tiniest fluctuations of external photonic fields but resistant to temperature variations as reflected in hysteresis of PE in response to temperature variations. These data suggest that blood is a highly cooperative non-equilibrium and non-linear system, whose components unceasingly interact in time and space. At least in part this property is provided by...
Unique properties of oxygen and of the reactions with reactive oxygen species (ROS) participation... more Unique properties of oxygen and of the reactions with reactive oxygen species (ROS) participation are considered, the multiple ways of ROS generation and utilization are discussed in view of evidence for the absolute necessity of ROS for the normal vital activity. Many difficulties in the realization of the real role of ROS in vital activity are caused by the attitude to them only as to chemical substances, while they should be considered in the first place as the major participants of continuous flows of highly non-linear processes in which electron excited species emerge. These processes play a significant role in energy and informational flows in all the living systems. We suggest that the mechanisms of biological action of ROS are determined by the structural patterns (frequency-amplitude patterns of electron excited states generation and their relaxation) of the processes with ROS participation taking place in the aqueous environs. Energy released in such reactions is used as a...
Addition of H2O2 in sub-millimolar concentrations to 1–5 mM Na/K-bicarbonate solutions initiates ... more Addition of H2O2 in sub-millimolar concentrations to 1–5 mM Na/K-bicarbonate solutions initiates in them a process accompanied with low-level photon emission amplified with luminol. Photon emission lasts without decay for many months in samples isolated from air and ambient light. Photon emission intensity reveals monthly and circadian rhythms. Amplitude of photon emission intensity from test-tubes filled with active solu-tions increases two- to threefold on periods coinciding with the eclipses of the moon and the sun. Preparations of water-soluble fullerenes in dilutions equivalent to their concentrations 10–13, 10–15 and 10–19–10–20 M increased photon emission two- to threefold while intermediate dilutions affected it much weaker. We suggest that addi-tion of H2O2 to aqueous bicarbonate solutions initiates in them cyclic chain reactions in which water is oxidized with oxygen. Bicarbonate may stabilize these cyclic reactions due to its ability to participate in free radical reactio...
Tienda online donde Comprar Biophotonics and Coherent Systems in Biology al precio 122,84 € de Be... more Tienda online donde Comprar Biophotonics and Coherent Systems in Biology al precio 122,84 € de Beloussov, L.V. | Voeikov, V.L. | Martynyuk, V.S., tienda de Libros de Medicina, Libros de Biologia - Bioinformatica
A pilot study of the effect of the antioxidant drug ethylmethylhydroxypyridine malate on indicato... more A pilot study of the effect of the antioxidant drug ethylmethylhydroxypyridine malate on indicators of oxidative stress in patients with chronic cerebral ischemia. At 6 day course administration investigated the antioxidant in these patients significantly accelerates the process of generation of superoxide anion radical, established by lucigenin-depended chemiluminescence that probably regulate a feedback mechanism oxidase systems. This increases the activity of superoxide dismutase, and reduced the concentration of secondary peroxidation product - malondialdehyde, making reasonable use of antioxidants in the treatment of this pathology.
One of the unresolved questions related to the mechanism of action of light negative air ions (re... more One of the unresolved questions related to the mechanism of action of light negative air ions (reactive oxygen species) produced by air ionizers upon humans and animals is transmission of these short-living chemical species upon long distances from the place of their origin. We discovered the phenomenon which may probably resolve this problem. When a thin layer of water hydrating a hygroscopic surface absorbs rare UV-photons capable to split water molecules a flash of photon emission in UV- and visible regions of spectrum is observed. This flash (or oxygen-dependent oxidative processes underlying it) initiate reactions accompanied with generation of electronic excitation in the air contacting water film. Excitation propagates through the air at macroscopic distances, and the level of propagating excitation increases with elevation of air humidity. When air humidity exceeds 50% air excitation gains oscillatory-wave character. This phenomenon may endow into the mechanism of action of ...
Hydrated fullerene C60 (HyFn) is a supramolecular object in which the nanosized fullerene molecul... more Hydrated fullerene C60 (HyFn) is a supramolecular object in which the nanosized fullerene molecule is enclosed in a multilayer shell of water molecules. Despite the fact that fullerene C60 is chemically rather inert, aqueous solutions of HyFn exhibit a wide spectrum of biological activity in particular in low and ultra-low concentrations. Thus, physical and chemical properties of aqueous solutions of HyFn in a wide range of its dilutions are of interest. Here we compared some physical and chemical properties of aqueous systems prepared by successive 100-fold dilutions of HyFn (10–7 M) with deionized water, with their intensive shaking at each stage up to the calculated HyFn concentration of 10–31 M and of the corresponding “dilutions” of deionized water prepared in the same manner (controls). We studied the character of рН changes in dilutions when titrating them with HCl and NaOH. It turned out that HyFn dilutions had significantly higher buffering capacity against acidification wi...
21st Century Science & Technology Carbonates (bicarbonate, carbonic acid, and CO2) are the necess... more 21st Century Science & Technology Carbonates (bicarbonate, carbonic acid, and CO2) are the necessary constituents of cell cytoplasm and of all biological liquids. The bicarbonate content is strictly maintained in the organism. Its deficiency results in impaired cell and tissue respiration, followed by the development of a variety of pathological states. Both normal and healing drinking waters are usually bicarbonate solutions, and supplementation with bicarbonate is a universal healing method in complementary medicine. However, the true mechanism of action of carbonates is still a matter of debate. We discovered that the addition of iron oxide Fe(II) salts to bicarbonate solutions induces a wave of photon emission. The intensity of the wave is boosted in the presence of luminol, the probe for the reactive oxygen species (ROS), indicating that spontaneous chain reactions with the participation of reactive oxygen species take place continuously in aqueous bicarbonate solutions. The ad...
One of the unresolved questions related to the mechanism of action of light negative air ions (re... more One of the unresolved questions related to the mechanism of action of light negative air ions (reactive oxygen species) produced by air ionizers upon humans and animals is transmission of these short-living chemical species upon long distances from the place of their origin. We discovered the phenomenon which may probably resolve this problem. When a thin layer of water hydrating a hygroscopic surface absorbs rare UV-photons capable to split water molecules a flash of photon emission in UV- and visible regions of spectrum is observed. This flash (or oxygen-dependent oxidative processes underlying it) initiate reactions accompanied with generation of electronic excitation in the air contacting water film. Excitation propagates through the air at macroscopic distances, and the level of propagating excitation increases with elevation of air humidity. When air humidity exceeds 50% air excitation gains oscillatory-wave character. This phenomenon may endow into the mechanism of action of ...
After much research in the field of biological oxidation, two main concepts of the mechanism of e... more After much research in the field of biological oxidation, two main concepts of the mechanism of energy gain were consecutively proposed--the concept of direct oxygen activation (analogous to combustion), and the concept of activation of hydrogen followed by gradual energy release (analogous to putrefaction). The latter concept currently dominates. According to it, practically all the energy required in life is gained initially in the form of ATP; the latter being synthesized mostly due to the classical oxidative phosphorylation process. Direct activation of oxygen is considered to be a secondary pathway in its utilization, unrelated to bioenergetics. Besides, this pathway seems to be risky, since reactive oxygen species (ROS) are produced on account of it. However, evidence has been accumulated that a considerable part of all oxygen consumption undergoes direct activation; and this share increases with energy demand. Recent data also argues that ROS are indispensable for regulating ...
Monitoring of spontaneous and luminophore amplified photon emission (PE) from non-diluted human b... more Monitoring of spontaneous and luminophore amplified photon emission (PE) from non-diluted human blood under resting conditions and artificially induced immune reaction revealed that blood is a continuous source of biophotons indicating that it persists in electronically excited state. This state is pumped through generation of electron excitation produced in reactive oxygen species (ROS) reactions. Excited state of blood and of neutrophil suspensions (primary sources of ROS in blood) is an oscillatory one suggesting of interaction between individual sources of electron excitation. Excited state of blood is extremely sensitive to the tiniest fluctuations of external photonic fields but resistant to temperature variations as reflected in hysteresis of PE in response to temperature variations. These data suggest that blood is a highly cooperative non-equilibrium and non-linear system, whose components unceasingly interact in time and space. At least in part this property is provided by...
Unique properties of oxygen and of the reactions with reactive oxygen species (ROS) participation... more Unique properties of oxygen and of the reactions with reactive oxygen species (ROS) participation are considered, the multiple ways of ROS generation and utilization are discussed in view of evidence for the absolute necessity of ROS for the normal vital activity. Many difficulties in the realization of the real role of ROS in vital activity are caused by the attitude to them only as to chemical substances, while they should be considered in the first place as the major participants of continuous flows of highly non-linear processes in which electron excited species emerge. These processes play a significant role in energy and informational flows in all the living systems. We suggest that the mechanisms of biological action of ROS are determined by the structural patterns (frequency-amplitude patterns of electron excited states generation and their relaxation) of the processes with ROS participation taking place in the aqueous environs. Energy released in such reactions is used as a...
Addition of H2O2 in sub-millimolar concentrations to 1–5 mM Na/K-bicarbonate solutions initiates ... more Addition of H2O2 in sub-millimolar concentrations to 1–5 mM Na/K-bicarbonate solutions initiates in them a process accompanied with low-level photon emission amplified with luminol. Photon emission lasts without decay for many months in samples isolated from air and ambient light. Photon emission intensity reveals monthly and circadian rhythms. Amplitude of photon emission intensity from test-tubes filled with active solu-tions increases two- to threefold on periods coinciding with the eclipses of the moon and the sun. Preparations of water-soluble fullerenes in dilutions equivalent to their concentrations 10–13, 10–15 and 10–19–10–20 M increased photon emission two- to threefold while intermediate dilutions affected it much weaker. We suggest that addi-tion of H2O2 to aqueous bicarbonate solutions initiates in them cyclic chain reactions in which water is oxidized with oxygen. Bicarbonate may stabilize these cyclic reactions due to its ability to participate in free radical reactio...
Tienda online donde Comprar Biophotonics and Coherent Systems in Biology al precio 122,84 € de Be... more Tienda online donde Comprar Biophotonics and Coherent Systems in Biology al precio 122,84 € de Beloussov, L.V. | Voeikov, V.L. | Martynyuk, V.S., tienda de Libros de Medicina, Libros de Biologia - Bioinformatica
A pilot study of the effect of the antioxidant drug ethylmethylhydroxypyridine malate on indicato... more A pilot study of the effect of the antioxidant drug ethylmethylhydroxypyridine malate on indicators of oxidative stress in patients with chronic cerebral ischemia. At 6 day course administration investigated the antioxidant in these patients significantly accelerates the process of generation of superoxide anion radical, established by lucigenin-depended chemiluminescence that probably regulate a feedback mechanism oxidase systems. This increases the activity of superoxide dismutase, and reduced the concentration of secondary peroxidation product - malondialdehyde, making reasonable use of antioxidants in the treatment of this pathology.
One of the unresolved questions related to the mechanism of action of light negative air ions (re... more One of the unresolved questions related to the mechanism of action of light negative air ions (reactive oxygen species) produced by air ionizers upon humans and animals is transmission of these short-living chemical species upon long distances from the place of their origin. We discovered the phenomenon which may probably resolve this problem. When a thin layer of water hydrating a hygroscopic surface absorbs rare UV-photons capable to split water molecules a flash of photon emission in UV- and visible regions of spectrum is observed. This flash (or oxygen-dependent oxidative processes underlying it) initiate reactions accompanied with generation of electronic excitation in the air contacting water film. Excitation propagates through the air at macroscopic distances, and the level of propagating excitation increases with elevation of air humidity. When air humidity exceeds 50% air excitation gains oscillatory-wave character. This phenomenon may endow into the mechanism of action of ...
Hydrated fullerene C60 (HyFn) is a supramolecular object in which the nanosized fullerene molecul... more Hydrated fullerene C60 (HyFn) is a supramolecular object in which the nanosized fullerene molecule is enclosed in a multilayer shell of water molecules. Despite the fact that fullerene C60 is chemically rather inert, aqueous solutions of HyFn exhibit a wide spectrum of biological activity in particular in low and ultra-low concentrations. Thus, physical and chemical properties of aqueous solutions of HyFn in a wide range of its dilutions are of interest. Here we compared some physical and chemical properties of aqueous systems prepared by successive 100-fold dilutions of HyFn (10–7 M) with deionized water, with their intensive shaking at each stage up to the calculated HyFn concentration of 10–31 M and of the corresponding “dilutions” of deionized water prepared in the same manner (controls). We studied the character of рН changes in dilutions when titrating them with HCl and NaOH. It turned out that HyFn dilutions had significantly higher buffering capacity against acidification wi...
21st Century Science & Technology Carbonates (bicarbonate, carbonic acid, and CO2) are the necess... more 21st Century Science & Technology Carbonates (bicarbonate, carbonic acid, and CO2) are the necessary constituents of cell cytoplasm and of all biological liquids. The bicarbonate content is strictly maintained in the organism. Its deficiency results in impaired cell and tissue respiration, followed by the development of a variety of pathological states. Both normal and healing drinking waters are usually bicarbonate solutions, and supplementation with bicarbonate is a universal healing method in complementary medicine. However, the true mechanism of action of carbonates is still a matter of debate. We discovered that the addition of iron oxide Fe(II) salts to bicarbonate solutions induces a wave of photon emission. The intensity of the wave is boosted in the presence of luminol, the probe for the reactive oxygen species (ROS), indicating that spontaneous chain reactions with the participation of reactive oxygen species take place continuously in aqueous bicarbonate solutions. The ad...
Low and Superlow Fields and Radiations in Biology and Medicine
Sci proceedings of the Congress
... more Low and Superlow Fields and Radiations in Biology and Medicine
Sci proceedings of the Congress
RUSSIAN ACADEMY OF SCIENCES SAINT-PETERSBURG SCIENTIFIC CENTER RUSSIAN ACADEMY OF SCIENCES GOVERNMENT OF SAINT-PETERSBURG NORTHWEST BRANCH OF THE RUSSIAN ACADEMY OF MEDICAL SCIENCES INSTITUTE FOR ANALYTICAL RESEARCH RUSSIAN ACADEMY OF SCIENCES SAINT-PETERSBURG STATE POLYTECHNICAL UNIVERSITY RUSSIAN STATE HYDROMETEOROLOGICAL UNIVERSITY SAINT PETERSBURG ELECTROTECHNICAL UNIVERSITY "LETI" THE INTERNATIONAL COMMITTEE FOR RESEARCH AND STUDY OF ENVIRONMENTAL FACTORS (CIFA) UKRAINIAN BIOPHYSICAL SOCIETY LTD "MS-BIO"
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Sci proceedings of the Congress
RUSSIAN ACADEMY OF SCIENCES
SAINT-PETERSBURG SCIENTIFIC CENTER RUSSIAN ACADEMY OF SCIENCES GOVERNMENT OF SAINT-PETERSBURG
NORTHWEST BRANCH OF THE RUSSIAN ACADEMY OF MEDICAL SCIENCES
INSTITUTE FOR ANALYTICAL RESEARCH RUSSIAN ACADEMY OF SCIENCES SAINT-PETERSBURG STATE POLYTECHNICAL UNIVERSITY
RUSSIAN STATE HYDROMETEOROLOGICAL UNIVERSITY
SAINT PETERSBURG ELECTROTECHNICAL UNIVERSITY "LETI"
THE INTERNATIONAL COMMITTEE FOR RESEARCH AND STUDY OF ENVIRONMENTAL FACTORS (CIFA) UKRAINIAN BIOPHYSICAL SOCIETY
LTD "MS-BIO"