In this article, a Ricci soliton and *-conformal Ricci soliton are examined in the framework of t... more In this article, a Ricci soliton and *-conformal Ricci soliton are examined in the framework of trans-Sasakian three-manifold. In the beginning of the paper, it is shown that a three-dimensional trans-Sasakian manifold of type (α,β) admits a Ricci soliton where the covariant derivative of potential vector field V in the direction of unit vector field ξ is orthogonal to ξ. It is also demonstrated that if the structure functions meet α2=β2, then the covariant derivative of V in the direction of ξ is a constant multiple of ξ. Furthermore, the nature of scalar curvature is evolved when the manifold of type (α,β) satisfies *-conformal Ricci soliton, provided α≠0. Finally, an example is presented to verify the findings.
We study conformal $$\eta$$ η -Einstein solitons on the framework of trans-Sasakian manifold in d... more We study conformal $$\eta$$ η -Einstein solitons on the framework of trans-Sasakian manifold in dimension three. Existence of conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold is discussed. Then we find some results on trans-Sasakian manifold which are conformal $$\eta$$ η -Einstein solitons where the Ricci tensor is cyclic parallel and Codazzi type. We also consider some curvature conditions with addition to conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold. We also use torse-forming vector fields in addition to conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold. Finally, an example of conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold is constructed.
In this paper, we give the parametric equation of the Bishop frame for a timelike sweeping surfac... more In this paper, we give the parametric equation of the Bishop frame for a timelike sweeping surface with a unit speed timelike curve in Minkowski 3-space. We introduce a new geometric invariant to explain the geometric properties and local singularities of this timelike surface. We derive the sufficient and necessary conditions for this timelike surface to be a timelike developable ruled surface. Afterwards, we take advantage of singularity theory to give the classification of singularities of this timelike developable surface. Furthermore, we give some representative examples to show the applications of the theoretical results.
E. Study map is one of the most basic and powerful mathematical tools to study lines in line geom... more E. Study map is one of the most basic and powerful mathematical tools to study lines in line geometry, it has symmetry property. In this paper, based on the E. Study map, clear expressions were developed for the differential properties of one-parameter Lorentzian dual spherical movements that are coordinate systems independent. This eliminates the requirement of demanding coordinates transformations necessary in the determination of the canonical systems. With the proposed technique, new proofs for Euler–Savary, and Disteli’s formulae were derived.
The present paper is focused on time-like circular surfaces and singularities in Minkowski 3-spac... more The present paper is focused on time-like circular surfaces and singularities in Minkowski 3-space. The timelike circular surface with a constant radius could be swept out by moving a Lorentzian circle with its center while following a non-lightlike curve called the spine curve. In the present study, we have parameterized timelike circular surfaces and examined their geometric properties, such as singularities and striction curves, corresponding with those of ruled surfaces. After that, a different kind of timelike circular surface was determined and named the timelike roller coaster surface. Meanwhile, we support the results of this work with some examples.
The paper undertakes certain special forms of the quarter symmetric metric and non-metric connect... more The paper undertakes certain special forms of the quarter symmetric metric and non-metric connections on an ε-anti-Kähler manifold. Firstly, we deduce the relation between the Riemannian connection and the special forms of the quarter symmetric metric and non-metric connections. Then, we present some results concerning the torsion tensors of these connections. In addition, we find the forms of the curvature tensor, the Ricci curvature tensor and scalar curvature of such connections and we search the conditions for the ε-anti-Kähler manifold to be an Einstein space with respect to these connections. Finally, we study U(Ric)-vector fields with respect to these connections and give some results related to them.
We prove that if an η \eta -Einstein para-Kenmotsu manifold admits a conformal η \eta -Ricci soli... more We prove that if an η \eta -Einstein para-Kenmotsu manifold admits a conformal η \eta -Ricci soliton then it is Einstein. Next, we proved that a para-Kenmotsu metric as a conformal η \eta -Ricci soliton is Einstein if its potential vector field V V is infinitesimal paracontact transformation or collinear with the Reeb vector field. Furthermore, we prove that if a para-Kenmotsu manifold admits a gradient conformal η \eta -Ricci almost soliton and the Reeb vector field leaves the scalar curvature invariant then it is Einstein. We also construct an example of para-Kenmotsu manifold that admits conformal η \eta -Ricci soliton and satisfy our results. We also have studied conformal η \eta -Ricci soliton in three-dimensional para-cosymplectic manifolds.
The present research paper consists of the study of an η1-Einstein soliton in general relativisti... more The present research paper consists of the study of an η1-Einstein soliton in general relativistic space-time with a torse-forming potential vector field. Besides this, we try to evaluate the characterization of the metrics when the space-time with a semi-symmetric energy-momentum tensor admits an η1-Einstein soliton, whose potential vector field is torse-forming. In adition, certain curvature conditions on the space-time that admit an η1-Einstein soliton are explored and build up the importance of the Laplace equation on the space-time in terms of η1-Einstein soliton. Lastly, we have given some physical accomplishment with the connection of dust fluid, dark fluid and radiation era in general relativistic space-time admitting an η1-Einstein soliton.
Stem cell senescence and exhaustion are closely related to organ failure and individual aging, wh... more Stem cell senescence and exhaustion are closely related to organ failure and individual aging, which not only induces age-related diseases, but also hinders stem cell applications in regenerative medicine. Thus, it's imminent to find effective ways to delay and retrieve stem cell senescence. Metabolic abnormalities are one of the main characteristics of age-associated declines in stem cell function. Understanding the underlying mechanisms may reveal potential strategies for ameliorating age-associated phenotypes and treating age-related diseases. This review focuses on recent advances in the association between metabolism including glucose, lipid, glutamine and NAD+ metabolism and stem cell senescence, as well as the other properties like proliferation and differentiation. Layers of studies are summarized to demonstrate how metabolism varies in senescent stem cells and how metabolic reprogramming regulates stem cell senescence. Additionally, we mentioned some recent progress in therapeutic strategies to rejuvenate dysfunctional aged stem cells. Finally, a brief conclusion about the prospect of metabolic regulation as a potential strategy for rescuing stem cell senescence is displayed. Stem cell senescence is induced by the metabolic reprogramming. The metabolic alterations of glucose, lipid, glutamine and NAD+ can conversely facilitate or inhibit stem cell senescence. Glycolysis, OXPHOS and PPP are all attenuated. But gluconeogenesis alterations still remain unclear. In lipid metabolisms, both FAO and DNL are suppressed. As for the glutamine metabolism, stem cells' dependence on glutamine is enhanced. Last, NAD+ metabolism undergoes a down-regulated synthesis and up-regulated consumption. All these alterations can be potential targets for reversing stem cell senescence.
The present paper aims to deliberate the geometric composition of a perfect fluid spacetime with ... more The present paper aims to deliberate the geometric composition of a perfect fluid spacetime with torse-forming vector field ξ in connection with conformal Ricci–Yamabe metric and conformal η-Ricci–Yamabe metric. We delineate the conditions for conformal Ricci–Yamabe soliton to be expanding, steady or shrinking. We also discuss conformal Ricci–Yamabe soliton on some special types of perfect fluid spacetime such as dust fluid, dark fluid and radiation era. Furthermore, we design conformal η-Ricci–Yamabe soliton to find its characteristics in a perfect fluid spacetime and lastly acquired Laplace equation from conformal η-Ricci–Yamabe soliton equation when the potential vector field ξ of the soliton is of gradient type. Overall, the main novelty of the paper is to study the geometrical phenomena and characteristics of our newly introduced conformal Ricci–Yamabe and conformal η-Ricci–Yamabe solitons to apply their existence in a perfect fluid spacetime.
Circulation: Cardiovascular Quality and Outcomes, 2011
Introduction: Clinical trials report the mean benefits and risks of a treatment for a population,... more Introduction: Clinical trials report the mean benefits and risks of a treatment for a population, which can mask the heterogeneity of risks and benefits for individual patients. Recognizing and communicating individual patients’ risks may support translation of trial results into practice. Methods: Using data from 12,907 ACS patients undergoing percutaneous coronary intervention (PCI) in TRITON-TIMI 38, we fit separate multivariable logistic regression models to predict major ischemia (cardiac death, MI & stroke) and bleeding (TIMI major/minor) risk with both prasugrel and clopidogrel. We built full models using variables selected a priori , then created a more parsimonious model by sequentially removing variables explaining the least variance until the reduced model R 2 in prediction of the full model fell below 0.95. Potential interactions were tested between treatment and all covariates. Results: Models are presented in the Figure; the ischemia risk model included interactions of...
Circulation: Cardiovascular Quality and Outcomes, 2014
Background: Diabetes mellitus (DM) is a common comorbidity in patients hospitalized with an acute... more Background: Diabetes mellitus (DM) is a common comorbidity in patients hospitalized with an acute myocardial infarction (AMI), and, in some cases, the AMI hospitalization represents the first opportunity to recognize and treat DM. We sought to understand both the prevalence of incident DM and its rate of recognition among AMI patients without DM diagnosis on admission. Methods: Patients in a 24-site U.S. AMI registry had A1C assessed at a core lab, which was blinded to clinicians. Patients could also have A1C drawn for clinical purposes. We defined DM based on A1C≥6.5% or, if A1C level was missing, based on ≥2 fasting glucose levels ≥126 mg/dL or ≥1 fasting glucose ≥126 mg/dL AND glucose at presentation ≥200 mg/dL. DM was considered recognized if the patient received DM education during the hospitalization or a DM medication at discharge. Multivariable, hierarchical logistic regression examined factors associated with recognition. Treatment with DM medications was evaluated at 6-mon...
This paper presents MiniBox, the first two-way sandbox for x86 native code. MiniBox not only isol... more This paper presents MiniBox, the first two-way sandbox for x86 native code. MiniBox not only isolates the memory space between OS protection modules and an application, but also provides a minimized and secure communication interface between OS protection modules and the application. MiniBox is cross-platform and can be applied in Platform-as-a-Service (PaaS) cloud computing to provide two-way protection between a customer's application and the cloud platform OS. We implement a prototype of MiniBox on both Intel and AMD multi-core systems and port several applications toMiniBox. Evaluation results show thatMiniBox is efficient and practical.
We develop a special-purpose hypervisor called TrustVisor that facilitates the execution of secur... more We develop a special-purpose hypervisor called TrustVisor that facilitates the execution of security-sensitive code in isolation from commodity OSes and applications. TrustVisor provides code and execution integrity as well as data secrecy and integrity for protected code, even in the presence of a compromised OS. These strong properties can be attested to a remote verifier. TrustVisor only adds 5306 lines to the TCB (over half of which is for cryptographic operations). TrustVisor imposes less than 7% overhead in the common case. This overhead is largely the result of today's x86 hardware virtualization support.
In this paper, we obtain some topological characterizations for the warping function of a warped ... more In this paper, we obtain some topological characterizations for the warping function of a warped product pointwise semi-slant submanifold of the form Ωn=NTl×fNϕk in a complex projective space CP2m(4). Additionally, we will find certain restrictions on the warping function f, Dirichlet energy function E(f), and first non-zero eigenvalue λ1 to prove that stable l-currents do not exist and also that the homology groups have vanished in Ωn. As an application of the non-existence of the stable currents in Ωn, we show that the fundamental group π1(Ωn) is trivial and Ωn is simply connected under the same extrinsic conditions. Further, some similar conclusions are provided for CR-warped product submanifolds.
The present paper is to deliberate the class of $ \epsilon $-Kenmotsu manifolds which admits conf... more The present paper is to deliberate the class of $ \epsilon $-Kenmotsu manifolds which admits conformal $ \eta $-Ricci soliton. Here, we study some special types of Ricci tensor in connection with the conformal $ \eta $-Ricci soliton of $ \epsilon $-Kenmotsu manifolds. Moving further, we investigate some curvature conditions admitting conformal $ \eta $-Ricci solitons on $ \epsilon $-Kenmotsu manifolds. Next, we consider gradient conformal $ \eta $-Ricci solitons and we present a characterization of the potential function. Finally, we develop an illustrative example for the existence of conformal $ \eta $-Ricci soliton on $ \epsilon $-Kenmotsu manifold.
The importance of microRNAs in various diseases has been demonstrated, but their potential role i... more The importance of microRNAs in various diseases has been demonstrated, but their potential role in the pathogenesis of renal fibrosis needs to further research. We have profiled changes in microRNA levels in human kidney proximal tubular cell line HK-2 with TGF-β treatment and identified significantly altered miRNAs. miR-129-5p, was one of the significant down-regulated miRNAs in experimental models. PDPK1 was a potential target gene of miR-129-5p and luciferase assay analysis identified PDPK1 as a new direct target gene of miR-129-5p. Further re - search indicated that miR-129-5p suppressed PDPK1 mRNA and protein levels in HK-2 cells. miR-129-5p inhibited EMT via PDPK1 in HK-2 cells. In a conclusion, our findings suggested that miR-129-5p may function as a suppressor in renal fibrosis by targeting PDPK1.
2018 IEEE International Power Electronics and Application Conference and Exposition (PEAC), 2018
This paper investigates a high efficiency inverter design for EV. It firstly compares the inverte... more This paper investigates a high efficiency inverter design for EV. It firstly compares the inverter with respect to topologies, device selections and modulation scheme at key operating points of a typical driving cycle. Secondarily the thermal design with air cooling is discussed. Then a two-level inverter prototype is built. Finally, testing of the inverter prototype with passive load is provided.
Autism is the most common clinical developmental disorder in children. The Childhood Autism Ratin... more Autism is the most common clinical developmental disorder in children. The Childhood Autism Rating Scale (CARS) and Autistic Behavior Checklist (ABC) are the most commonly used assessment scales for diagnosing autism. The aim of this study is to compare the diagnostic validities of CARS and ABC based on a large Chinese sample. A total of 474 children with suspected autism spectrum disorder (ASD) were screened by CARS and ABC. Receiver operating characteristic (ROC) curve analysis was performed and it showed that the area-under-the-curve values of CARS is higher than ABC significantly (p < 0.05) and the suggested cutoff values of CARS and ABC were 34 and 67, respectively. It indicated that CARS is superior to ABC in the Chinese population with suspected ASD.
The outline of this research article is to initiate the development of a ∗-conformal η-Ricci–Yama... more The outline of this research article is to initiate the development of a ∗-conformal η-Ricci–Yamabe soliton in α-Cosymplectic manifolds according to the quarter-symmetric metric connection. Here, we have established some curvature properties of α-Cosymplectic manifolds in regard to the quarter-symmetric metric connection. Further, the attributes of the soliton when the manifold gratifies a quarter-symmetric metric connection have been displayed in this article. Later, we picked up the Laplace equation from ∗-conformal η-Ricci–Yamabe soliton equation when the potential vector field ξ of the soliton is of gradient type, admitting quarter-symmetric metric connection. Next, we evolved the nature of the soliton when the vector field’s conformal killing reveals a quarter-symmetric metric connection. We show an example of a 5-dimensional α-cosymplectic metric as a ∗-conformal η-Ricci–Yamabe soliton acknowledges quarter-symmetric metric connection to prove our results.
In this article, a Ricci soliton and *-conformal Ricci soliton are examined in the framework of t... more In this article, a Ricci soliton and *-conformal Ricci soliton are examined in the framework of trans-Sasakian three-manifold. In the beginning of the paper, it is shown that a three-dimensional trans-Sasakian manifold of type (α,β) admits a Ricci soliton where the covariant derivative of potential vector field V in the direction of unit vector field ξ is orthogonal to ξ. It is also demonstrated that if the structure functions meet α2=β2, then the covariant derivative of V in the direction of ξ is a constant multiple of ξ. Furthermore, the nature of scalar curvature is evolved when the manifold of type (α,β) satisfies *-conformal Ricci soliton, provided α≠0. Finally, an example is presented to verify the findings.
We study conformal $$\eta$$ η -Einstein solitons on the framework of trans-Sasakian manifold in d... more We study conformal $$\eta$$ η -Einstein solitons on the framework of trans-Sasakian manifold in dimension three. Existence of conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold is discussed. Then we find some results on trans-Sasakian manifold which are conformal $$\eta$$ η -Einstein solitons where the Ricci tensor is cyclic parallel and Codazzi type. We also consider some curvature conditions with addition to conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold. We also use torse-forming vector fields in addition to conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold. Finally, an example of conformal $$\eta$$ η -Einstein solitons on trans-Sasakian manifold is constructed.
In this paper, we give the parametric equation of the Bishop frame for a timelike sweeping surfac... more In this paper, we give the parametric equation of the Bishop frame for a timelike sweeping surface with a unit speed timelike curve in Minkowski 3-space. We introduce a new geometric invariant to explain the geometric properties and local singularities of this timelike surface. We derive the sufficient and necessary conditions for this timelike surface to be a timelike developable ruled surface. Afterwards, we take advantage of singularity theory to give the classification of singularities of this timelike developable surface. Furthermore, we give some representative examples to show the applications of the theoretical results.
E. Study map is one of the most basic and powerful mathematical tools to study lines in line geom... more E. Study map is one of the most basic and powerful mathematical tools to study lines in line geometry, it has symmetry property. In this paper, based on the E. Study map, clear expressions were developed for the differential properties of one-parameter Lorentzian dual spherical movements that are coordinate systems independent. This eliminates the requirement of demanding coordinates transformations necessary in the determination of the canonical systems. With the proposed technique, new proofs for Euler–Savary, and Disteli’s formulae were derived.
The present paper is focused on time-like circular surfaces and singularities in Minkowski 3-spac... more The present paper is focused on time-like circular surfaces and singularities in Minkowski 3-space. The timelike circular surface with a constant radius could be swept out by moving a Lorentzian circle with its center while following a non-lightlike curve called the spine curve. In the present study, we have parameterized timelike circular surfaces and examined their geometric properties, such as singularities and striction curves, corresponding with those of ruled surfaces. After that, a different kind of timelike circular surface was determined and named the timelike roller coaster surface. Meanwhile, we support the results of this work with some examples.
The paper undertakes certain special forms of the quarter symmetric metric and non-metric connect... more The paper undertakes certain special forms of the quarter symmetric metric and non-metric connections on an ε-anti-Kähler manifold. Firstly, we deduce the relation between the Riemannian connection and the special forms of the quarter symmetric metric and non-metric connections. Then, we present some results concerning the torsion tensors of these connections. In addition, we find the forms of the curvature tensor, the Ricci curvature tensor and scalar curvature of such connections and we search the conditions for the ε-anti-Kähler manifold to be an Einstein space with respect to these connections. Finally, we study U(Ric)-vector fields with respect to these connections and give some results related to them.
We prove that if an η \eta -Einstein para-Kenmotsu manifold admits a conformal η \eta -Ricci soli... more We prove that if an η \eta -Einstein para-Kenmotsu manifold admits a conformal η \eta -Ricci soliton then it is Einstein. Next, we proved that a para-Kenmotsu metric as a conformal η \eta -Ricci soliton is Einstein if its potential vector field V V is infinitesimal paracontact transformation or collinear with the Reeb vector field. Furthermore, we prove that if a para-Kenmotsu manifold admits a gradient conformal η \eta -Ricci almost soliton and the Reeb vector field leaves the scalar curvature invariant then it is Einstein. We also construct an example of para-Kenmotsu manifold that admits conformal η \eta -Ricci soliton and satisfy our results. We also have studied conformal η \eta -Ricci soliton in three-dimensional para-cosymplectic manifolds.
The present research paper consists of the study of an η1-Einstein soliton in general relativisti... more The present research paper consists of the study of an η1-Einstein soliton in general relativistic space-time with a torse-forming potential vector field. Besides this, we try to evaluate the characterization of the metrics when the space-time with a semi-symmetric energy-momentum tensor admits an η1-Einstein soliton, whose potential vector field is torse-forming. In adition, certain curvature conditions on the space-time that admit an η1-Einstein soliton are explored and build up the importance of the Laplace equation on the space-time in terms of η1-Einstein soliton. Lastly, we have given some physical accomplishment with the connection of dust fluid, dark fluid and radiation era in general relativistic space-time admitting an η1-Einstein soliton.
Stem cell senescence and exhaustion are closely related to organ failure and individual aging, wh... more Stem cell senescence and exhaustion are closely related to organ failure and individual aging, which not only induces age-related diseases, but also hinders stem cell applications in regenerative medicine. Thus, it's imminent to find effective ways to delay and retrieve stem cell senescence. Metabolic abnormalities are one of the main characteristics of age-associated declines in stem cell function. Understanding the underlying mechanisms may reveal potential strategies for ameliorating age-associated phenotypes and treating age-related diseases. This review focuses on recent advances in the association between metabolism including glucose, lipid, glutamine and NAD+ metabolism and stem cell senescence, as well as the other properties like proliferation and differentiation. Layers of studies are summarized to demonstrate how metabolism varies in senescent stem cells and how metabolic reprogramming regulates stem cell senescence. Additionally, we mentioned some recent progress in therapeutic strategies to rejuvenate dysfunctional aged stem cells. Finally, a brief conclusion about the prospect of metabolic regulation as a potential strategy for rescuing stem cell senescence is displayed. Stem cell senescence is induced by the metabolic reprogramming. The metabolic alterations of glucose, lipid, glutamine and NAD+ can conversely facilitate or inhibit stem cell senescence. Glycolysis, OXPHOS and PPP are all attenuated. But gluconeogenesis alterations still remain unclear. In lipid metabolisms, both FAO and DNL are suppressed. As for the glutamine metabolism, stem cells' dependence on glutamine is enhanced. Last, NAD+ metabolism undergoes a down-regulated synthesis and up-regulated consumption. All these alterations can be potential targets for reversing stem cell senescence.
The present paper aims to deliberate the geometric composition of a perfect fluid spacetime with ... more The present paper aims to deliberate the geometric composition of a perfect fluid spacetime with torse-forming vector field ξ in connection with conformal Ricci–Yamabe metric and conformal η-Ricci–Yamabe metric. We delineate the conditions for conformal Ricci–Yamabe soliton to be expanding, steady or shrinking. We also discuss conformal Ricci–Yamabe soliton on some special types of perfect fluid spacetime such as dust fluid, dark fluid and radiation era. Furthermore, we design conformal η-Ricci–Yamabe soliton to find its characteristics in a perfect fluid spacetime and lastly acquired Laplace equation from conformal η-Ricci–Yamabe soliton equation when the potential vector field ξ of the soliton is of gradient type. Overall, the main novelty of the paper is to study the geometrical phenomena and characteristics of our newly introduced conformal Ricci–Yamabe and conformal η-Ricci–Yamabe solitons to apply their existence in a perfect fluid spacetime.
Circulation: Cardiovascular Quality and Outcomes, 2011
Introduction: Clinical trials report the mean benefits and risks of a treatment for a population,... more Introduction: Clinical trials report the mean benefits and risks of a treatment for a population, which can mask the heterogeneity of risks and benefits for individual patients. Recognizing and communicating individual patients’ risks may support translation of trial results into practice. Methods: Using data from 12,907 ACS patients undergoing percutaneous coronary intervention (PCI) in TRITON-TIMI 38, we fit separate multivariable logistic regression models to predict major ischemia (cardiac death, MI & stroke) and bleeding (TIMI major/minor) risk with both prasugrel and clopidogrel. We built full models using variables selected a priori , then created a more parsimonious model by sequentially removing variables explaining the least variance until the reduced model R 2 in prediction of the full model fell below 0.95. Potential interactions were tested between treatment and all covariates. Results: Models are presented in the Figure; the ischemia risk model included interactions of...
Circulation: Cardiovascular Quality and Outcomes, 2014
Background: Diabetes mellitus (DM) is a common comorbidity in patients hospitalized with an acute... more Background: Diabetes mellitus (DM) is a common comorbidity in patients hospitalized with an acute myocardial infarction (AMI), and, in some cases, the AMI hospitalization represents the first opportunity to recognize and treat DM. We sought to understand both the prevalence of incident DM and its rate of recognition among AMI patients without DM diagnosis on admission. Methods: Patients in a 24-site U.S. AMI registry had A1C assessed at a core lab, which was blinded to clinicians. Patients could also have A1C drawn for clinical purposes. We defined DM based on A1C≥6.5% or, if A1C level was missing, based on ≥2 fasting glucose levels ≥126 mg/dL or ≥1 fasting glucose ≥126 mg/dL AND glucose at presentation ≥200 mg/dL. DM was considered recognized if the patient received DM education during the hospitalization or a DM medication at discharge. Multivariable, hierarchical logistic regression examined factors associated with recognition. Treatment with DM medications was evaluated at 6-mon...
This paper presents MiniBox, the first two-way sandbox for x86 native code. MiniBox not only isol... more This paper presents MiniBox, the first two-way sandbox for x86 native code. MiniBox not only isolates the memory space between OS protection modules and an application, but also provides a minimized and secure communication interface between OS protection modules and the application. MiniBox is cross-platform and can be applied in Platform-as-a-Service (PaaS) cloud computing to provide two-way protection between a customer's application and the cloud platform OS. We implement a prototype of MiniBox on both Intel and AMD multi-core systems and port several applications toMiniBox. Evaluation results show thatMiniBox is efficient and practical.
We develop a special-purpose hypervisor called TrustVisor that facilitates the execution of secur... more We develop a special-purpose hypervisor called TrustVisor that facilitates the execution of security-sensitive code in isolation from commodity OSes and applications. TrustVisor provides code and execution integrity as well as data secrecy and integrity for protected code, even in the presence of a compromised OS. These strong properties can be attested to a remote verifier. TrustVisor only adds 5306 lines to the TCB (over half of which is for cryptographic operations). TrustVisor imposes less than 7% overhead in the common case. This overhead is largely the result of today's x86 hardware virtualization support.
In this paper, we obtain some topological characterizations for the warping function of a warped ... more In this paper, we obtain some topological characterizations for the warping function of a warped product pointwise semi-slant submanifold of the form Ωn=NTl×fNϕk in a complex projective space CP2m(4). Additionally, we will find certain restrictions on the warping function f, Dirichlet energy function E(f), and first non-zero eigenvalue λ1 to prove that stable l-currents do not exist and also that the homology groups have vanished in Ωn. As an application of the non-existence of the stable currents in Ωn, we show that the fundamental group π1(Ωn) is trivial and Ωn is simply connected under the same extrinsic conditions. Further, some similar conclusions are provided for CR-warped product submanifolds.
The present paper is to deliberate the class of $ \epsilon $-Kenmotsu manifolds which admits conf... more The present paper is to deliberate the class of $ \epsilon $-Kenmotsu manifolds which admits conformal $ \eta $-Ricci soliton. Here, we study some special types of Ricci tensor in connection with the conformal $ \eta $-Ricci soliton of $ \epsilon $-Kenmotsu manifolds. Moving further, we investigate some curvature conditions admitting conformal $ \eta $-Ricci solitons on $ \epsilon $-Kenmotsu manifolds. Next, we consider gradient conformal $ \eta $-Ricci solitons and we present a characterization of the potential function. Finally, we develop an illustrative example for the existence of conformal $ \eta $-Ricci soliton on $ \epsilon $-Kenmotsu manifold.
The importance of microRNAs in various diseases has been demonstrated, but their potential role i... more The importance of microRNAs in various diseases has been demonstrated, but their potential role in the pathogenesis of renal fibrosis needs to further research. We have profiled changes in microRNA levels in human kidney proximal tubular cell line HK-2 with TGF-β treatment and identified significantly altered miRNAs. miR-129-5p, was one of the significant down-regulated miRNAs in experimental models. PDPK1 was a potential target gene of miR-129-5p and luciferase assay analysis identified PDPK1 as a new direct target gene of miR-129-5p. Further re - search indicated that miR-129-5p suppressed PDPK1 mRNA and protein levels in HK-2 cells. miR-129-5p inhibited EMT via PDPK1 in HK-2 cells. In a conclusion, our findings suggested that miR-129-5p may function as a suppressor in renal fibrosis by targeting PDPK1.
2018 IEEE International Power Electronics and Application Conference and Exposition (PEAC), 2018
This paper investigates a high efficiency inverter design for EV. It firstly compares the inverte... more This paper investigates a high efficiency inverter design for EV. It firstly compares the inverter with respect to topologies, device selections and modulation scheme at key operating points of a typical driving cycle. Secondarily the thermal design with air cooling is discussed. Then a two-level inverter prototype is built. Finally, testing of the inverter prototype with passive load is provided.
Autism is the most common clinical developmental disorder in children. The Childhood Autism Ratin... more Autism is the most common clinical developmental disorder in children. The Childhood Autism Rating Scale (CARS) and Autistic Behavior Checklist (ABC) are the most commonly used assessment scales for diagnosing autism. The aim of this study is to compare the diagnostic validities of CARS and ABC based on a large Chinese sample. A total of 474 children with suspected autism spectrum disorder (ASD) were screened by CARS and ABC. Receiver operating characteristic (ROC) curve analysis was performed and it showed that the area-under-the-curve values of CARS is higher than ABC significantly (p < 0.05) and the suggested cutoff values of CARS and ABC were 34 and 67, respectively. It indicated that CARS is superior to ABC in the Chinese population with suspected ASD.
The outline of this research article is to initiate the development of a ∗-conformal η-Ricci–Yama... more The outline of this research article is to initiate the development of a ∗-conformal η-Ricci–Yamabe soliton in α-Cosymplectic manifolds according to the quarter-symmetric metric connection. Here, we have established some curvature properties of α-Cosymplectic manifolds in regard to the quarter-symmetric metric connection. Further, the attributes of the soliton when the manifold gratifies a quarter-symmetric metric connection have been displayed in this article. Later, we picked up the Laplace equation from ∗-conformal η-Ricci–Yamabe soliton equation when the potential vector field ξ of the soliton is of gradient type, admitting quarter-symmetric metric connection. Next, we evolved the nature of the soliton when the vector field’s conformal killing reveals a quarter-symmetric metric connection. We show an example of a 5-dimensional α-cosymplectic metric as a ∗-conformal η-Ricci–Yamabe soliton acknowledges quarter-symmetric metric connection to prove our results.
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