Research Interests:
Research Interests:
Introduction: The rigid person syndrome is rare, characterized by blockade of the GAD enzyme, responsible for inhibiting muscle contraction. Although it is not mandatory for the diagnosis, most patients are positive for Anti-GAD.... more
Introduction: The rigid person syndrome is rare, characterized by blockade of the GAD enzyme, responsible for inhibiting muscle contraction. Although it is not mandatory for the diagnosis, most patients are positive for Anti-GAD. Objectives: To report a case of rigid person syndrome seen at Hospital Geral de Goiânia. Methods: Information was obtained through clinical follow-up in a neurology ward and outpatient clinic. Results: Patient, female, 32 years old, complaining of paresthesia ascending to upper limbs, worsening over a period of six months with paresis with gait impairment, increased tone and muscle spasms. Patient with multiple consultations with a neurologist and psychiatrist, using polypharmacy. During hospitalization, the patient reported severe pain in the limbs. On examination, she had grade 3 strength and quadrisegmental hypertonia with intermittent periods of generalized spasm, exacerbated during periods of greater anxiety. Hypothesis of rigid person syndrome was rai...
