Antidepressants, frequently prescribed in depression and anxiety disorders, are known to be respo... more Antidepressants, frequently prescribed in depression and anxiety disorders, are known to be responsible for an increase in bleeding. Yet, it has rarely been reported that SSRI treatment has unfavorable effects on hemostasis. The most frequently reported side effects of SSRIs on the hematologic system are prolonged bleeding time, impaired thrombocyte aggregation and activity. Here we present a case in whom ecchymotic lesions occurred with esscitalopram and fluoxetine, which disappeared with reboxetine. [Cukurova Med J 2015; 40(Suppl 1): 90-93]
113 Özet Amaç: Bilişsel davranışçı kuram, alkolizmde patolojik içme davranışının ortaya çıkma ve ... more 113 Özet Amaç: Bilişsel davranışçı kuram, alkolizmde patolojik içme davranışının ortaya çıkma ve sürme nedenlerinin anlaşılması için kuramsal bir çerçeve sunmasının yanında, bu bozukluğu tedavi edecek klinik teknik için kavramsal bir dayanak sunmaktadır. Bu kapsam doğrultusunda planladığımız çalışmada alkol bağımlılarında bilişsel özelliklerin araştırılması amaçlanmıştır. Yöntem: Çalışmaya alkol bağımlılığı tanısıyla yatmakta olan 79 hasta ve bağımlı olmayan ancak alkol kullanımı olan 31 sağlıklı kontrolden oluşan 2 grup dahil edildi. İşlevsel olmayan bilişsel özelliklerin saptanması için her iki gruba da fonksiyonel olmayan tutumlar (FOTÖ) ölçeği verilirken hasta grubuna ayrıca DSM-IV için yapılandırılmış klinik görüşme (Structured Clinical Interview for DSM-III-R) SCID I ve II taraması yapıldı. Veriler SPSS 17 programında değerlendirildi. Bulgular: FOTÖ toplam puanları ile mükemmeliyetçi tutum, onaylanma ihtiyacı ve bağımsız tutum alt ölçek puanları, hasta grubunda kontrol grubuna...
Objective: It was aimed to determine sociodemographic characteristics and anxiety complaints of i... more Objective: It was aimed to determine sociodemographic characteristics and anxiety complaints of individuals admitted with psychiatric complaints after an earthquake in Elazig province, and to investigate the factors affecting anxiety levels. Materials and Methods: Individuals who begun to seek psychiatric help following the earthquake and fulfilled the following criteria were included: age >17 years; literacy; and absence of mental retardation or psychotic disorder. A sociodemographic data collection form, the Traumatic Life Events Questionnaire, and the Beck Anxiety Inventory were applied. Results: The mean age of the participants (n=101) was 39.2±17.3 years, and 67.3% of the participants were females. Damage to home and loss of a relative were in question in 55.4% and 12.9% of the participants, respectively. A previous traumatic experience and a history of psychiatric treatment were present in 31.6% and 9.9% of the participants, respectively. The most common previous traumatic ...
Background Immunological mechanisms may be responsible for the development and maintenance of sch... more Background Immunological mechanisms may be responsible for the development and maintenance of schizophrenia symptoms. Aim The aim of this study is to measure tumour necrosis factor-alpha (TNF-α), soluble tumour necrosis factor-alpha receptor I (sTNF-αRI), and soluble tumour necrosis factor-alpha receptor II (sTNF-αRII) levels in patients with schizophrenia and healthy individuals, and to determine their relationship with the symptoms of schizophrenia. Methods Serum TNF-α, sTNF-αRI and sTNF-αRII levels were measured. The Positive and Negative Syndrome Scale (PANSS) was administered for patients with schizophrenia (n = 35), and the results were compared with healthy controls (n = 30). Hierarchical regression analyses were undertaken to predict the levels of TNF-α, sTNF-αRI and sTNF-αRII. Results No significant difference was observed in TNF-α levels, but sTNF-αRI and sTNF-αRII levels were lower in patients with schizophrenia. Serum sTNF-αRI and sTNF-αRII levels were found to be negati...
10th International Congress on Psychopharmacology &am... more 10th International Congress on Psychopharmacology & 6th International Symposium on Child and Adolescent Psychopharmacology[Abstract:0110] [Addiction]Cessation of cigarette smoking in adolescents: s...
Progress in Neuro-psychopharmacology & Biological Psychiatry, 2007
An association or a casual link has been proposed between the neuroendocrinological and neuroimmu... more An association or a casual link has been proposed between the neuroendocrinological and neuroimmunological changes attributed to either depression or cancer. This study investigated whether breast cancer patients with and without major depression exhibit plasma interleukin-6 abnormalities and dexamethasone suppression test results. Four groups, each consisting of 30 women (1—healthy women, 2—patients with major depression, 3—breast cancer patients without major
Bipolar duygudurum bozukluğunda eşik altı belirtilerin fark edilmemesinin bazı vakaların tanı ve ... more Bipolar duygudurum bozukluğunda eşik altı belirtilerin fark edilmemesinin bazı vakaların tanı ve tedavisini güçleştirdiği gözlenmektedir. Bu yelpazede yer alan hastaların işlevsellik düzeyinde önemli bozulmalar olduğu, hastanın hastalığı kabul sürecinin ve tedavi uyumunun bozulduğu düşünülmektedir. Bu yazıda bipolar yelpaze kavramı içinde değerlendirilen bir vakanın tanı ve tedavi süreci anlatılacaktır.
---
It has been reported that the correct diagnosis and treatment are delayed when subsyndromal bipolar mood disorder symptoms are overlooked. Patients in this spectrum are also reported to have a dimished level of functioning, and these patients also fail to accept their diagnosis, and therefore there is a low level of treatment adherence. This case report focuses on the diagnosis and treatment of a patient in the bipolar spectrum.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2006
It is not scarce that patients experience various extrapyramidal symptoms (EPS) during antidepres... more It is not scarce that patients experience various extrapyramidal symptoms (EPS) during antidepressant drug therapy. Thus, choice of an antidepressant drug in case of extrapyramidal side effects, at present, is a dilemma. Escitalopram, which is a recently marketed selective serotonin reuptake inhibitors (SSRI), has no such reputation. There is just one case reported for tianeptine that induced abnormal involuntary movements/extrapyramidal side effects. We would like to present a case that was successfully managed with bupropion which had developed EPS during 2 different SSRI (sertraline and escitalopram) and tianeptine therapy.
Antidepressants, frequently prescribed in depression and anxiety disorders, are known to be respo... more Antidepressants, frequently prescribed in depression and anxiety disorders, are known to be responsible for an increase in bleeding. Yet, it has rarely been reported that SSRI treatment has unfavorable effects on hemostasis. The most frequently reported side effects of SSRIs on the hematologic system are prolonged bleeding time, impaired thrombocyte aggregation and activity. Here we present a case in whom ecchymotic lesions occurred with esscitalopram and fluoxetine, which disappeared with reboxetine. [Cukurova Med J 2015; 40(Suppl 1): 90-93]
113 Özet Amaç: Bilişsel davranışçı kuram, alkolizmde patolojik içme davranışının ortaya çıkma ve ... more 113 Özet Amaç: Bilişsel davranışçı kuram, alkolizmde patolojik içme davranışının ortaya çıkma ve sürme nedenlerinin anlaşılması için kuramsal bir çerçeve sunmasının yanında, bu bozukluğu tedavi edecek klinik teknik için kavramsal bir dayanak sunmaktadır. Bu kapsam doğrultusunda planladığımız çalışmada alkol bağımlılarında bilişsel özelliklerin araştırılması amaçlanmıştır. Yöntem: Çalışmaya alkol bağımlılığı tanısıyla yatmakta olan 79 hasta ve bağımlı olmayan ancak alkol kullanımı olan 31 sağlıklı kontrolden oluşan 2 grup dahil edildi. İşlevsel olmayan bilişsel özelliklerin saptanması için her iki gruba da fonksiyonel olmayan tutumlar (FOTÖ) ölçeği verilirken hasta grubuna ayrıca DSM-IV için yapılandırılmış klinik görüşme (Structured Clinical Interview for DSM-III-R) SCID I ve II taraması yapıldı. Veriler SPSS 17 programında değerlendirildi. Bulgular: FOTÖ toplam puanları ile mükemmeliyetçi tutum, onaylanma ihtiyacı ve bağımsız tutum alt ölçek puanları, hasta grubunda kontrol grubuna...
Objective: It was aimed to determine sociodemographic characteristics and anxiety complaints of i... more Objective: It was aimed to determine sociodemographic characteristics and anxiety complaints of individuals admitted with psychiatric complaints after an earthquake in Elazig province, and to investigate the factors affecting anxiety levels. Materials and Methods: Individuals who begun to seek psychiatric help following the earthquake and fulfilled the following criteria were included: age >17 years; literacy; and absence of mental retardation or psychotic disorder. A sociodemographic data collection form, the Traumatic Life Events Questionnaire, and the Beck Anxiety Inventory were applied. Results: The mean age of the participants (n=101) was 39.2±17.3 years, and 67.3% of the participants were females. Damage to home and loss of a relative were in question in 55.4% and 12.9% of the participants, respectively. A previous traumatic experience and a history of psychiatric treatment were present in 31.6% and 9.9% of the participants, respectively. The most common previous traumatic ...
Background Immunological mechanisms may be responsible for the development and maintenance of sch... more Background Immunological mechanisms may be responsible for the development and maintenance of schizophrenia symptoms. Aim The aim of this study is to measure tumour necrosis factor-alpha (TNF-α), soluble tumour necrosis factor-alpha receptor I (sTNF-αRI), and soluble tumour necrosis factor-alpha receptor II (sTNF-αRII) levels in patients with schizophrenia and healthy individuals, and to determine their relationship with the symptoms of schizophrenia. Methods Serum TNF-α, sTNF-αRI and sTNF-αRII levels were measured. The Positive and Negative Syndrome Scale (PANSS) was administered for patients with schizophrenia (n = 35), and the results were compared with healthy controls (n = 30). Hierarchical regression analyses were undertaken to predict the levels of TNF-α, sTNF-αRI and sTNF-αRII. Results No significant difference was observed in TNF-α levels, but sTNF-αRI and sTNF-αRII levels were lower in patients with schizophrenia. Serum sTNF-αRI and sTNF-αRII levels were found to be negati...
10th International Congress on Psychopharmacology &am... more 10th International Congress on Psychopharmacology & 6th International Symposium on Child and Adolescent Psychopharmacology[Abstract:0110] [Addiction]Cessation of cigarette smoking in adolescents: s...
Progress in Neuro-psychopharmacology & Biological Psychiatry, 2007
An association or a casual link has been proposed between the neuroendocrinological and neuroimmu... more An association or a casual link has been proposed between the neuroendocrinological and neuroimmunological changes attributed to either depression or cancer. This study investigated whether breast cancer patients with and without major depression exhibit plasma interleukin-6 abnormalities and dexamethasone suppression test results. Four groups, each consisting of 30 women (1—healthy women, 2—patients with major depression, 3—breast cancer patients without major
Bipolar duygudurum bozukluğunda eşik altı belirtilerin fark edilmemesinin bazı vakaların tanı ve ... more Bipolar duygudurum bozukluğunda eşik altı belirtilerin fark edilmemesinin bazı vakaların tanı ve tedavisini güçleştirdiği gözlenmektedir. Bu yelpazede yer alan hastaların işlevsellik düzeyinde önemli bozulmalar olduğu, hastanın hastalığı kabul sürecinin ve tedavi uyumunun bozulduğu düşünülmektedir. Bu yazıda bipolar yelpaze kavramı içinde değerlendirilen bir vakanın tanı ve tedavi süreci anlatılacaktır.
---
It has been reported that the correct diagnosis and treatment are delayed when subsyndromal bipolar mood disorder symptoms are overlooked. Patients in this spectrum are also reported to have a dimished level of functioning, and these patients also fail to accept their diagnosis, and therefore there is a low level of treatment adherence. This case report focuses on the diagnosis and treatment of a patient in the bipolar spectrum.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2006
It is not scarce that patients experience various extrapyramidal symptoms (EPS) during antidepres... more It is not scarce that patients experience various extrapyramidal symptoms (EPS) during antidepressant drug therapy. Thus, choice of an antidepressant drug in case of extrapyramidal side effects, at present, is a dilemma. Escitalopram, which is a recently marketed selective serotonin reuptake inhibitors (SSRI), has no such reputation. There is just one case reported for tianeptine that induced abnormal involuntary movements/extrapyramidal side effects. We would like to present a case that was successfully managed with bupropion which had developed EPS during 2 different SSRI (sertraline and escitalopram) and tianeptine therapy.
Uploads
Papers by levent turhan
---
It has been reported that the correct diagnosis and treatment are delayed when subsyndromal bipolar mood disorder symptoms are overlooked. Patients in this spectrum are also reported to have a dimished level of functioning, and these patients also fail to accept their diagnosis, and therefore there is a low level of treatment adherence. This case report focuses on the diagnosis and treatment of a patient in the bipolar spectrum.
---
It has been reported that the correct diagnosis and treatment are delayed when subsyndromal bipolar mood disorder symptoms are overlooked. Patients in this spectrum are also reported to have a dimished level of functioning, and these patients also fail to accept their diagnosis, and therefore there is a low level of treatment adherence. This case report focuses on the diagnosis and treatment of a patient in the bipolar spectrum.