Md Sadique Hussain is a hard-working, dedicated, and enthusiastic person with good interpersonal and organizational skills, who is flexible and full of energy. He has completed his Bachelor of Pharmacy from Lovely Professional University and currently pursuing his Masters of Pharmacy (Pharmacology) from Jaipur National University. He has over 40 publications that have been cited over 70 times, and his publication h-index is 5. He has been serving as a reviewer for many journals and as an editorial board member also. He is currently working on the Antioxidant Properties of Bixa orellana. Phone: +91-8235463635 Address: School of Pharmaceutical Sciences, Jaipur National University, Jaipur (302017), Rajasthan, India.
Asian Journal of Pharmaceutical and Clinical Research, Mar 7, 2021
After cardiovascular diseases, in most developed nations cancer is the second leading cause of mo... more After cardiovascular diseases, in most developed nations cancer is the second leading cause of mortality. Additional to the rising tumor-related behaviors, especially smoking in developing nations, the global prevalence of cancer keeps climbing primarily cos of the aging and expansion of the global population. Lung carcinoma, liver carcinoma, intestinal carcinoma, colorectal carcinoma, breast carcinoma, stomach carcinoma, etc., are the largest global burden of cancer types. More than half of all cases of cancer and mortality are considered preventable globally. There are food components that, beyond basic nutrition, provide health benefits. These functional foods are known to do more than just provide nutrients because they help to sustain health and thereby decrease the risk of disease. In recent times, functional foods have acquired enormous importance for their anticipated visualized involvement in the treatment of various pathologies such as cancer. To see the impact of functional foods on wellbeing or cancer or associated states, there are very few researches performed worldwide. Several functional foods derived from diverse sources, such as plants, animals, and microbial sources, have noticeable anticancer effects. In this review, we show light on the different types of cancers and also highlighted different functional foods that can help in the prevention as well as treatment of different types of carcinoma.
Haemovigilance is considered to be the collection of monitoring measures that encompass the entir... more Haemovigilance is considered to be the collection of monitoring measures that encompass the entire transfusions process ranging from monitoring of blood to the prevention of blood-related disease. The term hemovigilance originated from the word pharmacovigilance, which comprises operations and methods to gather intelligence valuable in overseeing pharmaceutical goods, particularly adverse drug responses in humans, and to scientifically assess such data. This follows the reporting system which includes the enhancement of patient safety. It also includes learning from failures that result in certain system changes and thus prevents the associated errors. It also includes all key parties and organizes numerous operations among blood banks, transfusion facilities, and hospital caregivers. The majority of affluent nations now use Haemovigilance to track adverse responses and occurrences connected with blood donation and transfusion. This mini-review sheds the light on an overview of haem...
International Journal of Applied Pharmaceutics, Mar 7, 2021
Respiratory diseases are the leading source of morbidity and death for millions around the world ... more Respiratory diseases are the leading source of morbidity and death for millions around the world of all ages. A 2019 coronavirus outbreak has occurred in China and is spread quickly throughout nearly all across the world. To introduce prevention measures that have contributed to a sudden upturn in the rate of cases around the globe, several nations responded too late. It has prompted nations to close the borders, halted companies, kept people inside their homes, and numerous other measures to prevent their spread. We systematically searched on Google scholar, PubMed, LitCovid, and MedRxiv using the search terms coronavirus, severe acute respiratory syndrome, 2019-nCoV, SARS-CoV-2, SARS-CoV, MERS-CoV, COVID-19, and vaccine for published articles. Present or performed clinical studies were found on the ClinicalTrials. gov, the Chinese Clinical Trial Registry, and the International Clinical Trial Registry site using the disease searches phrase coronavirus infection. Many repurposed drugs, including antivirals, antibiotics, monoclonal antibodies, corticosteroids, and others, were found to be effective against the novel COVID-19. Governments, private firms, researchers, and non-profit organizations are working hard to create a COVID-19 vaccine. In addition to the new medicines and old drug clinical testing, SARS-CoV-2 vaccines must also be designed and developed. Moreover, positive news in the development of vaccines suggests that new vaccines will be available on the market soon and a bowl of immunity against this virus can be established, thus limiting the spread and eradication of this deadly virus from the surface of the world as with so many viruses.
International Journal of Contemporary Pediatrics , 2023
The objective is to describe an uncommon case of Hirschsprung's disease (HD), also called congeni... more The objective is to describe an uncommon case of Hirschsprung's disease (HD), also called congenital megacolon. The lack of neuronal ganglion cells from the submucosal and muscular nerve plexuses throughout a segment of varied length characterizes HD. Approx 94% of HD cases are diagnosed below the age of 5 years. A 3 years old male patient was admitted to the male surgery ward under a pediatric surgeon with the chief complaints of chronic constipation since birth with a history of delayed passage of meconium. The patient was diagnosed with a case of HD at the age of 1 year for which he was operated on colostomy was performed with multiple biopsies from narrowed rectosigmoid, from the transitional zone, and from colostomy stoma which confirmed the decision to make colostomy at the ganglionated segment of the colon based on the clinical picture during surgery. Biopsy report of narrowed rectosigmoid segment showed the absence of ganglion cells, while colostomy stoma and dilated proximal colon showed the presence of ganglion cells. The patient underwent a surgical procedure named pull-through surgery for HD, a martin's modification of the Duhamel operation.
International Journal of Pharmacy and Pharmaceutical Sciences, Dec 1, 2020
Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus... more Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus (COVID-19), which was emerged from Wuhan in China, originated by the novel coronavirus 2019 (SARS-CoV-2). COVID-19 is a viral illness, which is occurring on a large scale in every nation of the globe. Symptoms of coronavirus mainly include fever, fatigue, cough, headache, pneumonia and in severe condition, there is respiratory distress. The deadly virus alarmed the world to be on high alert as the number of rising cases and the death toll rising as the day passes. Methods: We have searched for articles of preference and interest systematically in sources like Google Scholar, PubMed, and other outlets. Results: Management in the case of diabetes is really necessary to decrease their mortality. Certain management parameters need to be followed to take care of patients suffering from both diseases. Conclusion: In this review, we highlighted the role of different medicines like chloroquine, lopinavir, and hydroxychloroquine for the remedy of this pandemic. We also discussed the chest Computed tomography functions and Real-time polymerase chain reaction for the screening of the outbreak. The center of attention of this review majorly on the care of diabetes throughout the time of the COVID-19 epidemic.
International Journal of Pharmaceutical Sciences Review and Research
Unexpected or unintended pregnancy is a global health concern. Young women who are pregnant are r... more Unexpected or unintended pregnancy is a global health concern. Young women who are pregnant are refused contraception care in many nations. For women, reversible methods of contraception with long-acting methods such as intrauterine devices (IUDs) proved more productive than short-acting methods including tablets and condoms. We systematically searched on Google scholar, PubMed, LitCovid, and MedRxiv using the search terms unintended pregnancy, contraception, implants, and IUD/IUS for published articles. The available IUDs now provide nearly complete childbirth protection although have few complications. Implantable contraceptives are commonly practiced all around the globe. Implants are among the most effective and reliable contraceptive strategies available. The Food and Drug Administration (FDA) of the United States in 1990, approved the Norplant contraceptive. The IUDs and implants apart from being successful contraceptives have a variety of harmful effects, which led the develo...
International Journal of Scientific Research in Science and Technology
The present review is based mainly on papers published between 2000 and 2020 and gives informatio... more The present review is based mainly on papers published between 2000 and 2020 and gives information about the properties of the Vitamins and Carotenoids in chemical and biological systems and its possible role in preventing several diseases. The main aim of this report is to highlight its role as an immunopathological applications, also reported are bioactive properties that may influence the development of foam cells and protection against endothelial cell damage.
International Journal of Pharmacy and Pharmaceutical Sciences, 2012
Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus... more Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus (COVID-19), which was emerged from Wuhan in China, originated by the novel coronavirus 2019 (SARS-CoV-2). COVID-19 is a viral illness, which is occurring on a large scale in every nation of the globe. Symptoms of coronavirus mainly include fever, fatigue, cough, headache, pneumonia and in severe condition, there is respiratory distress. The deadly virus alarmed the world to be on high alert as the number of rising cases and the death toll rising as the day passes. Methods: We have searched for articles of preference and interest systematically in sources like Google Scholar, PubMed, and other outlets. Results: Management in the case of diabetes is really necessary to decrease their mortality. Certain management parameters need to be followed to take care of patients suffering from both diseases. Conclusion: In this review, we highlighted the role of different medicines like chloroquine,...
International Journal of Applied Pharmaceutics, 2021
Respiratory diseases are the leading source of morbidity and death for millions around the world ... more Respiratory diseases are the leading source of morbidity and death for millions around the world of all ages. A 2019 coronavirus outbreak has occurred in China and is spread quickly throughout nearly all across the world. To introduce prevention measures that have contributed to a sudden upturn in the rate of cases around the globe, several nations responded too late. It has prompted nations to close the borders, halted companies, kept people inside their homes, and numerous other measures to prevent their spread. We systematically searched on Google scholar, PubMed, LitCovid, and MedRxiv using the search terms coronavirus, severe acute respiratory syndrome, 2019-nCoV, SARS-CoV-2, SARS-CoV, MERS-CoV, COVID-19, and vaccine for published articles. Present or performed clinical studies were found on the ClinicalTrials. gov, the Chinese Clinical Trial Registry, and the International Clinical Trial Registry site using the disease searches phrase coronavirus infection. Many repurposed drugs, including antivirals, antibiotics, monoclonal antibodies, corticosteroids, and others, were found to be effective against the novel COVID-19. Governments, private firms, researchers, and non-profit organizations are working hard to create a COVID-19 vaccine. In addition to the new medicines and old drug clinical testing, SARS-CoV-2 vaccines must also be designed and developed. Moreover, positive news in the development of vaccines suggests that new vaccines will be available on the market soon and a bowl of immunity against this virus can be established, thus limiting the spread and eradication of this deadly virus from the surface of the world as with so many viruses.
Asian Journal of Pharmaceutical and Clinical Research, 2021
After cardiovascular diseases, in most developed nations cancer is the second l... more After cardiovascular diseases, in most developed nations cancer is the second leading cause of mortality. Additional to the rising tumor-related behaviors, especially smoking in developing nations, the global prevalence of cancer keeps climbing primarily cos of the aging and expansion of the global population. Lung carcinoma, liver carcinoma, intestinal carcinoma, colorectal carcinoma, breast carcinoma, stomach carcinoma, etc., are the largest global burden of cancer types. More than half of all cases of cancer and mortality are considered preventable globally. There are food components that, beyond basic nutrition, provide health benefits. These functional foods are known to do more than just provide nutrients because they help to sustain health and thereby decrease the risk of disease. In recent times, functional foods have acquired enormous importance for their anticipated visualized involvement in the treatment of various pathologies such as cancer. To see the impact of functional foods on wellbeing or cancer or associated states, there are very few researches performed worldwide. Several functional foods derived from diverse sources, such as plants, animals, and microbial sources, have noticeable anticancer effects. In this review, we show light on the different types of cancers and also highlighted different functional foods that can help in the prevention as well as treatment of different types of carcinoma.
Disputes in kidney disease (KD) incidence and progression are commonly believed to be based upon ... more Disputes in kidney disease (KD) incidence and progression are commonly believed to be based upon group differences in the prevalence of risk factors for KDs, such as diabetes, hypertension, and obesity. But the prevalence of these comorbidity disorders does not fully explain the increased rate of developments in high-risk populations from chronic kidney disease (CKD). Renal diseases arise as renal function losses eventually resulting in total kidney failure. There is no complete understanding of the processes underlying the causes and development of KDs. The kidneys are a common target organ for the toxicity of different environmental compounds and agents from contact. We must recognize both chemical and pathological pathways and factors that could alter the susceptibility of injury to understand the risk to human health from exposures like these. At present, the test for early disease, predicting disease progression or monitoring therapeutic response is not sufficiently sensitive or specified. Despite several advances in treatment and understanding acute renal failure (ARF) pathogenesis, there persist conflict, ambiguity, and lack of certainty on many aspects in that field. The incidence, etiology, and clinical characteristics of RF are important in promoting preventative strategies and the use of sufficient resources for managing the disease. The article contains brief information about kidney failure, different KDs, their risk factor, prevention and also contains numerous herbs that are effective in the treatment of KDs.
International Journal of Pharmacy and Pharmaceutical Sciences, 2020
Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus... more Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus (COVID-19), which was emerged from Wuhan in China, originated by the novel coronavirus 2019 (SARS-CoV-2). COVID-19 is a viral illness, which is occurring on a large scale in every nation of the globe. Symptoms of coronavirus mainly include fever, fatigue, cough, headache, pneumonia and in severe condition, there is respiratory distress. The deadly virus alarmed the world to be on high alert as the number of rising cases and the death toll rising as the day passes. Methods: We have searched for articles of preference and interest systematically in sources like Google Scholar, PubMed, and other outlets. Results: Management in the case of diabetes is really necessary to decrease their mortality. Certain management parameters need to be followed to take care of patients suffering from both diseases. Conclusion: In this review, we highlighted the role of different medicines like chloroquine, lopinavir, and hydroxychloroquine for the remedy of this pandemic. We also discussed the chest Computed tomography functions and Real-time polymerase chain reaction for the screening of the outbreak. The center of attention of this review majorly on the care of diabetes throughout the time of the COVID-19 epidemic.
Medicinal plants contain several phytoconstituents that are used for treatment of common bacteria... more Medicinal plants contain several phytoconstituents that are used for treatment of common bacterial infections. Microbial activity cause serious damage to living organisms. In the present study ethanolic extracts were prepared from Bixa orellana leaves and fruit, Simarouba glauca leaves and Ocimum tenuiflorum leaves. The extracts prepared from these plants showed a wide spectrum of antibacterial activity against gram negative Pseudomonas aeruginosa and Escherichia coli and gram-positive Streptococci and Staphylococci aureus bacteria by disc diffusion method and growth inhibition assay.
World Journal of Pharmaceutical and Life Science, 2020
Microbial activity causes serious damage to living organisms. In this study, ethanolic extracts w... more Microbial activity causes serious damage to living organisms. In this study, ethanolic extracts were prepared from leaves of Persea americana Mill. Pimenta dioica (L.) Merr., Cinnamomum tamala (Buch.-Ham.) T. Nees & Eberm. and Cinnamomum verum J. Presl. The ethanolic extracts prepared from these plants exhibited broad spectrum antibacterial activity when evaluated against gram-positive bacteria Streptococci spp. and Staphylococci aureus and gram-negative Escherichia coli and Pseudomonas aeruginosa by disc diffusion method and growth inhibition assay.
International Journal of Scientific Research in Science and Technology, 2020
The present review is based mainly on papers published between 2000 and 2020 and gives informatio... more The present review is based mainly on papers published between 2000 and 2020 and gives information about the properties of the Vitamins and Carotenoids in chemical and biological systems and its possible role in preventing several diseases. The main aim of this report is to highlight its role as an immunopathological applications, also reported are bioactive properties that may influence the development of foam cells and protection against endothelial cell damage.
International Journal of Creative Research Thoughts , 2020
Male breast cancer (MBC) is an infrequent and uncommon condition. It accounts 1% than other cance... more Male breast cancer (MBC) is an infrequent and uncommon condition. It accounts 1% than other cancer diagnosed in men. The rationale for low incidence among men is due to difference in hormonal environment and relatively poor breast tissue count in men. The disease is also diagnosed at later stages because of lack of awareness. In Asia most of the males hide about this disease due to social psychology. There is limited literature and published data on MBC due to low incidence of disease. This review deals with etiology, pathology, risk factors, treatment and psychological trauma in MBC patients. While in both genders breast carcinomas share similar features, significant variations exist. Most studies are very limited on the men with breast cancer. Therefore, most evidence on male breast cancer is extracted from female research. However, we will learn more about them when a lot of these little studies on male breast cancer are put together. This review stresses on the occurrence, etiology, clinical characteristics, diagnosis, treatment, pathology, survival and MBC-related prognostic factors.
Asian Journal of Pharmaceutical and Clinical Research, Mar 7, 2021
After cardiovascular diseases, in most developed nations cancer is the second leading cause of mo... more After cardiovascular diseases, in most developed nations cancer is the second leading cause of mortality. Additional to the rising tumor-related behaviors, especially smoking in developing nations, the global prevalence of cancer keeps climbing primarily cos of the aging and expansion of the global population. Lung carcinoma, liver carcinoma, intestinal carcinoma, colorectal carcinoma, breast carcinoma, stomach carcinoma, etc., are the largest global burden of cancer types. More than half of all cases of cancer and mortality are considered preventable globally. There are food components that, beyond basic nutrition, provide health benefits. These functional foods are known to do more than just provide nutrients because they help to sustain health and thereby decrease the risk of disease. In recent times, functional foods have acquired enormous importance for their anticipated visualized involvement in the treatment of various pathologies such as cancer. To see the impact of functional foods on wellbeing or cancer or associated states, there are very few researches performed worldwide. Several functional foods derived from diverse sources, such as plants, animals, and microbial sources, have noticeable anticancer effects. In this review, we show light on the different types of cancers and also highlighted different functional foods that can help in the prevention as well as treatment of different types of carcinoma.
Haemovigilance is considered to be the collection of monitoring measures that encompass the entir... more Haemovigilance is considered to be the collection of monitoring measures that encompass the entire transfusions process ranging from monitoring of blood to the prevention of blood-related disease. The term hemovigilance originated from the word pharmacovigilance, which comprises operations and methods to gather intelligence valuable in overseeing pharmaceutical goods, particularly adverse drug responses in humans, and to scientifically assess such data. This follows the reporting system which includes the enhancement of patient safety. It also includes learning from failures that result in certain system changes and thus prevents the associated errors. It also includes all key parties and organizes numerous operations among blood banks, transfusion facilities, and hospital caregivers. The majority of affluent nations now use Haemovigilance to track adverse responses and occurrences connected with blood donation and transfusion. This mini-review sheds the light on an overview of haem...
International Journal of Applied Pharmaceutics, Mar 7, 2021
Respiratory diseases are the leading source of morbidity and death for millions around the world ... more Respiratory diseases are the leading source of morbidity and death for millions around the world of all ages. A 2019 coronavirus outbreak has occurred in China and is spread quickly throughout nearly all across the world. To introduce prevention measures that have contributed to a sudden upturn in the rate of cases around the globe, several nations responded too late. It has prompted nations to close the borders, halted companies, kept people inside their homes, and numerous other measures to prevent their spread. We systematically searched on Google scholar, PubMed, LitCovid, and MedRxiv using the search terms coronavirus, severe acute respiratory syndrome, 2019-nCoV, SARS-CoV-2, SARS-CoV, MERS-CoV, COVID-19, and vaccine for published articles. Present or performed clinical studies were found on the ClinicalTrials. gov, the Chinese Clinical Trial Registry, and the International Clinical Trial Registry site using the disease searches phrase coronavirus infection. Many repurposed drugs, including antivirals, antibiotics, monoclonal antibodies, corticosteroids, and others, were found to be effective against the novel COVID-19. Governments, private firms, researchers, and non-profit organizations are working hard to create a COVID-19 vaccine. In addition to the new medicines and old drug clinical testing, SARS-CoV-2 vaccines must also be designed and developed. Moreover, positive news in the development of vaccines suggests that new vaccines will be available on the market soon and a bowl of immunity against this virus can be established, thus limiting the spread and eradication of this deadly virus from the surface of the world as with so many viruses.
International Journal of Contemporary Pediatrics , 2023
The objective is to describe an uncommon case of Hirschsprung's disease (HD), also called congeni... more The objective is to describe an uncommon case of Hirschsprung's disease (HD), also called congenital megacolon. The lack of neuronal ganglion cells from the submucosal and muscular nerve plexuses throughout a segment of varied length characterizes HD. Approx 94% of HD cases are diagnosed below the age of 5 years. A 3 years old male patient was admitted to the male surgery ward under a pediatric surgeon with the chief complaints of chronic constipation since birth with a history of delayed passage of meconium. The patient was diagnosed with a case of HD at the age of 1 year for which he was operated on colostomy was performed with multiple biopsies from narrowed rectosigmoid, from the transitional zone, and from colostomy stoma which confirmed the decision to make colostomy at the ganglionated segment of the colon based on the clinical picture during surgery. Biopsy report of narrowed rectosigmoid segment showed the absence of ganglion cells, while colostomy stoma and dilated proximal colon showed the presence of ganglion cells. The patient underwent a surgical procedure named pull-through surgery for HD, a martin's modification of the Duhamel operation.
International Journal of Pharmacy and Pharmaceutical Sciences, Dec 1, 2020
Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus... more Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus (COVID-19), which was emerged from Wuhan in China, originated by the novel coronavirus 2019 (SARS-CoV-2). COVID-19 is a viral illness, which is occurring on a large scale in every nation of the globe. Symptoms of coronavirus mainly include fever, fatigue, cough, headache, pneumonia and in severe condition, there is respiratory distress. The deadly virus alarmed the world to be on high alert as the number of rising cases and the death toll rising as the day passes. Methods: We have searched for articles of preference and interest systematically in sources like Google Scholar, PubMed, and other outlets. Results: Management in the case of diabetes is really necessary to decrease their mortality. Certain management parameters need to be followed to take care of patients suffering from both diseases. Conclusion: In this review, we highlighted the role of different medicines like chloroquine, lopinavir, and hydroxychloroquine for the remedy of this pandemic. We also discussed the chest Computed tomography functions and Real-time polymerase chain reaction for the screening of the outbreak. The center of attention of this review majorly on the care of diabetes throughout the time of the COVID-19 epidemic.
International Journal of Pharmaceutical Sciences Review and Research
Unexpected or unintended pregnancy is a global health concern. Young women who are pregnant are r... more Unexpected or unintended pregnancy is a global health concern. Young women who are pregnant are refused contraception care in many nations. For women, reversible methods of contraception with long-acting methods such as intrauterine devices (IUDs) proved more productive than short-acting methods including tablets and condoms. We systematically searched on Google scholar, PubMed, LitCovid, and MedRxiv using the search terms unintended pregnancy, contraception, implants, and IUD/IUS for published articles. The available IUDs now provide nearly complete childbirth protection although have few complications. Implantable contraceptives are commonly practiced all around the globe. Implants are among the most effective and reliable contraceptive strategies available. The Food and Drug Administration (FDA) of the United States in 1990, approved the Norplant contraceptive. The IUDs and implants apart from being successful contraceptives have a variety of harmful effects, which led the develo...
International Journal of Scientific Research in Science and Technology
The present review is based mainly on papers published between 2000 and 2020 and gives informatio... more The present review is based mainly on papers published between 2000 and 2020 and gives information about the properties of the Vitamins and Carotenoids in chemical and biological systems and its possible role in preventing several diseases. The main aim of this report is to highlight its role as an immunopathological applications, also reported are bioactive properties that may influence the development of foam cells and protection against endothelial cell damage.
International Journal of Pharmacy and Pharmaceutical Sciences, 2012
Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus... more Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus (COVID-19), which was emerged from Wuhan in China, originated by the novel coronavirus 2019 (SARS-CoV-2). COVID-19 is a viral illness, which is occurring on a large scale in every nation of the globe. Symptoms of coronavirus mainly include fever, fatigue, cough, headache, pneumonia and in severe condition, there is respiratory distress. The deadly virus alarmed the world to be on high alert as the number of rising cases and the death toll rising as the day passes. Methods: We have searched for articles of preference and interest systematically in sources like Google Scholar, PubMed, and other outlets. Results: Management in the case of diabetes is really necessary to decrease their mortality. Certain management parameters need to be followed to take care of patients suffering from both diseases. Conclusion: In this review, we highlighted the role of different medicines like chloroquine,...
International Journal of Applied Pharmaceutics, 2021
Respiratory diseases are the leading source of morbidity and death for millions around the world ... more Respiratory diseases are the leading source of morbidity and death for millions around the world of all ages. A 2019 coronavirus outbreak has occurred in China and is spread quickly throughout nearly all across the world. To introduce prevention measures that have contributed to a sudden upturn in the rate of cases around the globe, several nations responded too late. It has prompted nations to close the borders, halted companies, kept people inside their homes, and numerous other measures to prevent their spread. We systematically searched on Google scholar, PubMed, LitCovid, and MedRxiv using the search terms coronavirus, severe acute respiratory syndrome, 2019-nCoV, SARS-CoV-2, SARS-CoV, MERS-CoV, COVID-19, and vaccine for published articles. Present or performed clinical studies were found on the ClinicalTrials. gov, the Chinese Clinical Trial Registry, and the International Clinical Trial Registry site using the disease searches phrase coronavirus infection. Many repurposed drugs, including antivirals, antibiotics, monoclonal antibodies, corticosteroids, and others, were found to be effective against the novel COVID-19. Governments, private firms, researchers, and non-profit organizations are working hard to create a COVID-19 vaccine. In addition to the new medicines and old drug clinical testing, SARS-CoV-2 vaccines must also be designed and developed. Moreover, positive news in the development of vaccines suggests that new vaccines will be available on the market soon and a bowl of immunity against this virus can be established, thus limiting the spread and eradication of this deadly virus from the surface of the world as with so many viruses.
Asian Journal of Pharmaceutical and Clinical Research, 2021
After cardiovascular diseases, in most developed nations cancer is the second l... more After cardiovascular diseases, in most developed nations cancer is the second leading cause of mortality. Additional to the rising tumor-related behaviors, especially smoking in developing nations, the global prevalence of cancer keeps climbing primarily cos of the aging and expansion of the global population. Lung carcinoma, liver carcinoma, intestinal carcinoma, colorectal carcinoma, breast carcinoma, stomach carcinoma, etc., are the largest global burden of cancer types. More than half of all cases of cancer and mortality are considered preventable globally. There are food components that, beyond basic nutrition, provide health benefits. These functional foods are known to do more than just provide nutrients because they help to sustain health and thereby decrease the risk of disease. In recent times, functional foods have acquired enormous importance for their anticipated visualized involvement in the treatment of various pathologies such as cancer. To see the impact of functional foods on wellbeing or cancer or associated states, there are very few researches performed worldwide. Several functional foods derived from diverse sources, such as plants, animals, and microbial sources, have noticeable anticancer effects. In this review, we show light on the different types of cancers and also highlighted different functional foods that can help in the prevention as well as treatment of different types of carcinoma.
Disputes in kidney disease (KD) incidence and progression are commonly believed to be based upon ... more Disputes in kidney disease (KD) incidence and progression are commonly believed to be based upon group differences in the prevalence of risk factors for KDs, such as diabetes, hypertension, and obesity. But the prevalence of these comorbidity disorders does not fully explain the increased rate of developments in high-risk populations from chronic kidney disease (CKD). Renal diseases arise as renal function losses eventually resulting in total kidney failure. There is no complete understanding of the processes underlying the causes and development of KDs. The kidneys are a common target organ for the toxicity of different environmental compounds and agents from contact. We must recognize both chemical and pathological pathways and factors that could alter the susceptibility of injury to understand the risk to human health from exposures like these. At present, the test for early disease, predicting disease progression or monitoring therapeutic response is not sufficiently sensitive or specified. Despite several advances in treatment and understanding acute renal failure (ARF) pathogenesis, there persist conflict, ambiguity, and lack of certainty on many aspects in that field. The incidence, etiology, and clinical characteristics of RF are important in promoting preventative strategies and the use of sufficient resources for managing the disease. The article contains brief information about kidney failure, different KDs, their risk factor, prevention and also contains numerous herbs that are effective in the treatment of KDs.
International Journal of Pharmacy and Pharmaceutical Sciences, 2020
Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus... more Objective: As of now, the world is struggling with a serious pandemic of disease 2019 Coronavirus (COVID-19), which was emerged from Wuhan in China, originated by the novel coronavirus 2019 (SARS-CoV-2). COVID-19 is a viral illness, which is occurring on a large scale in every nation of the globe. Symptoms of coronavirus mainly include fever, fatigue, cough, headache, pneumonia and in severe condition, there is respiratory distress. The deadly virus alarmed the world to be on high alert as the number of rising cases and the death toll rising as the day passes. Methods: We have searched for articles of preference and interest systematically in sources like Google Scholar, PubMed, and other outlets. Results: Management in the case of diabetes is really necessary to decrease their mortality. Certain management parameters need to be followed to take care of patients suffering from both diseases. Conclusion: In this review, we highlighted the role of different medicines like chloroquine, lopinavir, and hydroxychloroquine for the remedy of this pandemic. We also discussed the chest Computed tomography functions and Real-time polymerase chain reaction for the screening of the outbreak. The center of attention of this review majorly on the care of diabetes throughout the time of the COVID-19 epidemic.
Medicinal plants contain several phytoconstituents that are used for treatment of common bacteria... more Medicinal plants contain several phytoconstituents that are used for treatment of common bacterial infections. Microbial activity cause serious damage to living organisms. In the present study ethanolic extracts were prepared from Bixa orellana leaves and fruit, Simarouba glauca leaves and Ocimum tenuiflorum leaves. The extracts prepared from these plants showed a wide spectrum of antibacterial activity against gram negative Pseudomonas aeruginosa and Escherichia coli and gram-positive Streptococci and Staphylococci aureus bacteria by disc diffusion method and growth inhibition assay.
World Journal of Pharmaceutical and Life Science, 2020
Microbial activity causes serious damage to living organisms. In this study, ethanolic extracts w... more Microbial activity causes serious damage to living organisms. In this study, ethanolic extracts were prepared from leaves of Persea americana Mill. Pimenta dioica (L.) Merr., Cinnamomum tamala (Buch.-Ham.) T. Nees & Eberm. and Cinnamomum verum J. Presl. The ethanolic extracts prepared from these plants exhibited broad spectrum antibacterial activity when evaluated against gram-positive bacteria Streptococci spp. and Staphylococci aureus and gram-negative Escherichia coli and Pseudomonas aeruginosa by disc diffusion method and growth inhibition assay.
International Journal of Scientific Research in Science and Technology, 2020
The present review is based mainly on papers published between 2000 and 2020 and gives informatio... more The present review is based mainly on papers published between 2000 and 2020 and gives information about the properties of the Vitamins and Carotenoids in chemical and biological systems and its possible role in preventing several diseases. The main aim of this report is to highlight its role as an immunopathological applications, also reported are bioactive properties that may influence the development of foam cells and protection against endothelial cell damage.
International Journal of Creative Research Thoughts , 2020
Male breast cancer (MBC) is an infrequent and uncommon condition. It accounts 1% than other cance... more Male breast cancer (MBC) is an infrequent and uncommon condition. It accounts 1% than other cancer diagnosed in men. The rationale for low incidence among men is due to difference in hormonal environment and relatively poor breast tissue count in men. The disease is also diagnosed at later stages because of lack of awareness. In Asia most of the males hide about this disease due to social psychology. There is limited literature and published data on MBC due to low incidence of disease. This review deals with etiology, pathology, risk factors, treatment and psychological trauma in MBC patients. While in both genders breast carcinomas share similar features, significant variations exist. Most studies are very limited on the men with breast cancer. Therefore, most evidence on male breast cancer is extracted from female research. However, we will learn more about them when a lot of these little studies on male breast cancer are put together. This review stresses on the occurrence, etiology, clinical characteristics, diagnosis, treatment, pathology, survival and MBC-related prognostic factors.
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Papers by Md Sadique Hussain