Journal of applied biomaterials & biomechanics : JABB
The rate of alkaline hydrolysis of medical grade poly(ethylene terephthalate) of grey, scoured, a... more The rate of alkaline hydrolysis of medical grade poly(ethylene terephthalate) of grey, scoured, and solvent extracted samples have been studied to understand their degradation behavior during surface modification which is used to produce antithrombus grafts. The changes in properties were examined using weight loss, mechanical properties loss and infrared spectrum. It was found that the rate of hydrolysis of grey sample was always slower than the scoured, and solvent extracted samples. The slower rate of degradation of the grey polyester is attributed to the presence of spin finishes in the polyester biomaterials. Further, different scouring methods also gave samples with varying rates of hydrolysis. This is due to the different spin finish removal efficiency of different scouring procedures. The weight loss (%) of the solvent extracted samples were the largest which demonstrated that the solvent extraction technique is perhaps the best to remove spin finish from the polyester. Thus...
Poly(ethylene Terephthalate): Application to Medical Textiles ... Mashiur Rahman 1 and GC East De... more Poly(ethylene Terephthalate): Application to Medical Textiles ... Mashiur Rahman 1 and GC East Department of Textile Industries, University of Leeds, Leeds LS2 9JT, UK ... Through the pioneering work of Carothers and Hill [1], poly(ethylene terephthalate) (PET:2GT) is made ...
The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology.... more The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology. Here, we present a simple method for patterning myosin II on a microstructured surface. Our findings indicate that UV/ozone treatment can be used to alter the ...
ABSTRACT Exposure to arsenic and subsequent development of atherosclerosis has been suggested to ... more ABSTRACT Exposure to arsenic and subsequent development of atherosclerosis has been suggested to be responsible for increased mortality. However, biochemical events for arsenic exposue-related atherosclerosis remain unknown. This study was aimed at investigating the associations of circulating biomarkers for atherosclerosis with arsenic exposure in the individuals exposed to arsenic in Bangladesh. A total of 324 study subjects from arsenicendemic and non-endemic areas in Bangladesh were recruited. Total cholesterol, LDL and HDL levels were lower in arsenic-endemic subjects than in non-endemic subjects. Oxidized LDL, CRP, ICAM- 1 and VCAM-1 levels were significantly higher in arsenic-endemic subjects than in non-endemic subjects. These circulating molecules also showed significant correlations with arsenic exposure metrics. Further, HDL, oxidized LDL and CRP showed dose-response relationships with arsenic exposure. All these associations may be the major features of arsenic-related atherosclerosis.
1The Graduate University for Advanced Studies, Institute for Molecular Science, Myodaiji, Okazaki... more 1The Graduate University for Advanced Studies, Institute for Molecular Science, Myodaiji, Okazaki 444-8585, Japan 2Institute for Molecular Science, Myodaiji, Okazaki 444-8585, Japan (Received October 30, 2003; accepted February 10, 2004; published June 29, 2004) Photoinduced ...
Elucidating the genetic, and neuronal bases for learned behavior is a central problem in neurosci... more Elucidating the genetic, and neuronal bases for learned behavior is a central problem in neuroscience. A leading system for neurogenetic discovery is the vinegar fly Drosophila melanogaster; fly memory research has identified genes and circuits that mediate aversive and appetitive learning. However, methods to study adaptive food-seeking behavior in this animal have lagged decades behind rodent feeding analysis, largely due to the challenges presented by their small scale. There is currently no method to dynamically control flies' access to food. In rodents, protocols that use dynamic food delivery are a central element of experimental paradigms that date back to the influential work of Skinner. This method is still commonly used in the analysis of learning, memory, addiction, feeding, and many other subjects in experimental psychology. The difficulty of microscale food delivery means this is not a technique used in fly behavior. In the present manuscript we describe a microfluidic chip integrated with machine vision and automation to dynamically control defined liquid food presentations and sensory stimuli. Strikingly, repeated presentations of food at a fixed location produced improvements in path efficiency during food approach. This shows that improved path choice is a learned behavior. Active control of food availability using this microfluidic system is a valuable addition to the methods currently available for the analysis of learned feeding behavior in flies.
The aim of this study was to characterize the binding profile as well as to notify the interactio... more The aim of this study was to characterize the binding profile as well as to notify the interaction of palmitic acid with metoprolol succinate at its binding site on albumin. The binding of metoprolol succinate to bovine serum albumin (BSA) was studied by equilibrium dialysis method (ED) at 27°C and pH 7.4, in order to have an insight in the binding chemistry of the drug to BSA in presence and absence of palmitic acid. The study was carried out using ranitidine as site-1 and diazepam as site-2 specific probe. Different analysis of binding of metoprolol succinate to bovine serum albumin suggested two sets of association constants: high affinity association constant (k1 = 11.0 x 10(5) M(-1)) with low capacity (n1 = 2) and low affinity association (k2 = 4.0×10(5) M(-1)) constant with high capacity (n2 = 8) at pH 7.4 and 27°C. During concurrent administration of palmitic acid and metoprolol succinate in presence or absence of ranitidine or diazepam, it was found that palmitic acid displa...
Asian Pacific Journal of Tropical Biomedicine, Oct 1, 2014
To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Molasses w... more To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Molasses were collected from open markets in different parts of Bangladesh. The presence of hydrose in selected molasses was detected using commercial kit. To evaluate the toxic effect of hydrose, Swiss albino male mice were divided into four groups. Group I was used as control, while Groups II, III and IV received hydrose mixing food (5, 10 and 25 g/kg food), respectively, and these supplementations were continued to the end of the study (16 weeks). Blood was collected from thoracic arteries of the mice under ether anesthesia and then organs were taken. To determine the effect of hydrose on host, blood indices related to liver, heart and kidney dysfunctions were measured.Creatinine and urea levels were significantly (P<0.05) increased in a dose dependent manner in hydrose treated mice, whereas calcium level was significantly decreased in hydrose exposed mice compared to control mice. Histological study of kidney showed the glomeruler inflammation, increased diameter of renal glomeruli and enlargement of proximal tubular lumen of kidneys of mice exposed to hydrose compared to that of control animals.The results of this study indicated that use of hydrose in molasses and other food preparations in Bangladesh may cause kidney impairment.
Journal of applied biomaterials & biomechanics : JABB
The rate of alkaline hydrolysis of medical grade poly(ethylene terephthalate) of grey, scoured, a... more The rate of alkaline hydrolysis of medical grade poly(ethylene terephthalate) of grey, scoured, and solvent extracted samples have been studied to understand their degradation behavior during surface modification which is used to produce antithrombus grafts. The changes in properties were examined using weight loss, mechanical properties loss and infrared spectrum. It was found that the rate of hydrolysis of grey sample was always slower than the scoured, and solvent extracted samples. The slower rate of degradation of the grey polyester is attributed to the presence of spin finishes in the polyester biomaterials. Further, different scouring methods also gave samples with varying rates of hydrolysis. This is due to the different spin finish removal efficiency of different scouring procedures. The weight loss (%) of the solvent extracted samples were the largest which demonstrated that the solvent extraction technique is perhaps the best to remove spin finish from the polyester. Thus...
Poly(ethylene Terephthalate): Application to Medical Textiles ... Mashiur Rahman 1 and GC East De... more Poly(ethylene Terephthalate): Application to Medical Textiles ... Mashiur Rahman 1 and GC East Department of Textile Industries, University of Leeds, Leeds LS2 9JT, UK ... Through the pioneering work of Carothers and Hill [1], poly(ethylene terephthalate) (PET:2GT) is made ...
The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology.... more The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology. Here, we present a simple method for patterning myosin II on a microstructured surface. Our findings indicate that UV/ozone treatment can be used to alter the ...
ABSTRACT Exposure to arsenic and subsequent development of atherosclerosis has been suggested to ... more ABSTRACT Exposure to arsenic and subsequent development of atherosclerosis has been suggested to be responsible for increased mortality. However, biochemical events for arsenic exposue-related atherosclerosis remain unknown. This study was aimed at investigating the associations of circulating biomarkers for atherosclerosis with arsenic exposure in the individuals exposed to arsenic in Bangladesh. A total of 324 study subjects from arsenicendemic and non-endemic areas in Bangladesh were recruited. Total cholesterol, LDL and HDL levels were lower in arsenic-endemic subjects than in non-endemic subjects. Oxidized LDL, CRP, ICAM- 1 and VCAM-1 levels were significantly higher in arsenic-endemic subjects than in non-endemic subjects. These circulating molecules also showed significant correlations with arsenic exposure metrics. Further, HDL, oxidized LDL and CRP showed dose-response relationships with arsenic exposure. All these associations may be the major features of arsenic-related atherosclerosis.
1The Graduate University for Advanced Studies, Institute for Molecular Science, Myodaiji, Okazaki... more 1The Graduate University for Advanced Studies, Institute for Molecular Science, Myodaiji, Okazaki 444-8585, Japan 2Institute for Molecular Science, Myodaiji, Okazaki 444-8585, Japan (Received October 30, 2003; accepted February 10, 2004; published June 29, 2004) Photoinduced ...
Elucidating the genetic, and neuronal bases for learned behavior is a central problem in neurosci... more Elucidating the genetic, and neuronal bases for learned behavior is a central problem in neuroscience. A leading system for neurogenetic discovery is the vinegar fly Drosophila melanogaster; fly memory research has identified genes and circuits that mediate aversive and appetitive learning. However, methods to study adaptive food-seeking behavior in this animal have lagged decades behind rodent feeding analysis, largely due to the challenges presented by their small scale. There is currently no method to dynamically control flies&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; access to food. In rodents, protocols that use dynamic food delivery are a central element of experimental paradigms that date back to the influential work of Skinner. This method is still commonly used in the analysis of learning, memory, addiction, feeding, and many other subjects in experimental psychology. The difficulty of microscale food delivery means this is not a technique used in fly behavior. In the present manuscript we describe a microfluidic chip integrated with machine vision and automation to dynamically control defined liquid food presentations and sensory stimuli. Strikingly, repeated presentations of food at a fixed location produced improvements in path efficiency during food approach. This shows that improved path choice is a learned behavior. Active control of food availability using this microfluidic system is a valuable addition to the methods currently available for the analysis of learned feeding behavior in flies.
The aim of this study was to characterize the binding profile as well as to notify the interactio... more The aim of this study was to characterize the binding profile as well as to notify the interaction of palmitic acid with metoprolol succinate at its binding site on albumin. The binding of metoprolol succinate to bovine serum albumin (BSA) was studied by equilibrium dialysis method (ED) at 27°C and pH 7.4, in order to have an insight in the binding chemistry of the drug to BSA in presence and absence of palmitic acid. The study was carried out using ranitidine as site-1 and diazepam as site-2 specific probe. Different analysis of binding of metoprolol succinate to bovine serum albumin suggested two sets of association constants: high affinity association constant (k1 = 11.0 x 10(5) M(-1)) with low capacity (n1 = 2) and low affinity association (k2 = 4.0×10(5) M(-1)) constant with high capacity (n2 = 8) at pH 7.4 and 27°C. During concurrent administration of palmitic acid and metoprolol succinate in presence or absence of ranitidine or diazepam, it was found that palmitic acid displa...
Asian Pacific Journal of Tropical Biomedicine, Oct 1, 2014
To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Molasses w... more To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Molasses were collected from open markets in different parts of Bangladesh. The presence of hydrose in selected molasses was detected using commercial kit. To evaluate the toxic effect of hydrose, Swiss albino male mice were divided into four groups. Group I was used as control, while Groups II, III and IV received hydrose mixing food (5, 10 and 25 g/kg food), respectively, and these supplementations were continued to the end of the study (16 weeks). Blood was collected from thoracic arteries of the mice under ether anesthesia and then organs were taken. To determine the effect of hydrose on host, blood indices related to liver, heart and kidney dysfunctions were measured.Creatinine and urea levels were significantly (P<0.05) increased in a dose dependent manner in hydrose treated mice, whereas calcium level was significantly decreased in hydrose exposed mice compared to control mice. Histological study of kidney showed the glomeruler inflammation, increased diameter of renal glomeruli and enlargement of proximal tubular lumen of kidneys of mice exposed to hydrose compared to that of control animals.The results of this study indicated that use of hydrose in molasses and other food preparations in Bangladesh may cause kidney impairment.
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Papers by Md. Mashiur Rahman