Md. Mashiur Rahman

The rate of alkaline hydrolysis of medical grade poly(ethylene terephthalate) of grey, scoured, and solvent extracted samples have been studied to understand their degradation behavior during surface modification which is used to produce antithrombus grafts. The changes in properties were examined using weight loss, mechanical properties loss and infrared spectrum. It was found that the rate of hydrolysis of grey sample was always slower than the scoured, and solvent extracted samples. The slower rate of degradation of the grey polyester is attributed to the presence of spin finishes in the polyester biomaterials. Further, different scouring methods also gave samples with varying rates of hydrolysis. This is due to the different spin finish removal efficiency of different scouring procedures. The weight loss (%) of the solvent extracted samples were the largest which demonstrated that the solvent extraction technique is perhaps the best to remove spin finish from the polyester. Thus...

Poly(ethylene Terephthalate): Application to Medical Textiles ... Mashiur Rahman 1 and GC East Department of Textile Industries, University of Leeds, Leeds LS2 9JT, UK ... Through the pioneering work of Carothers and Hill [1], poly(ethylene terephthalate) (PET:2GT) is made ...

The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology. Here, we present a simple method for patterning myosin II on a microstructured surface. Our findings indicate that UV/ozone treatment can be used to alter the ...

ABSTRACT Exposure to arsenic and subsequent development of atherosclerosis has been suggested to be responsible for increased mortality. However, biochemical events for arsenic exposue-related atherosclerosis remain unknown. This study was aimed at investigating the associations of circulating biomarkers for atherosclerosis with arsenic exposure in the individuals exposed to arsenic in Bangladesh. A total of 324 study subjects from arsenicendemic and non-endemic areas in Bangladesh were recruited. Total cholesterol, LDL and HDL levels were lower in arsenic-endemic subjects than in non-endemic subjects. Oxidized LDL, CRP, ICAM- 1 and VCAM-1 levels were significantly higher in arsenic-endemic subjects than in non-endemic subjects. These circulating molecules also showed significant correlations with arsenic exposure metrics. Further, HDL, oxidized LDL and CRP showed dose-response relationships with arsenic exposure. All these associations may be the major features of arsenic-related atherosclerosis.

1The Graduate University for Advanced Studies, Institute for Molecular Science, Myodaiji, Okazaki 444-8585, Japan 2Institute for Molecular Science, Myodaiji, Okazaki 444-8585, Japan (Received October 30, 2003; accepted February 10, 2004; published June 29, 2004) Photoinduced ...

Elucidating the genetic, and neuronal bases for learned behavior is a central problem in neuroscience. A leading system for neurogenetic discovery is the vinegar fly Drosophila melanogaster; fly memory research has identified genes and circuits that mediate aversive and appetitive learning. However, methods to study adaptive food-seeking behavior in this animal have lagged decades behind rodent feeding analysis, largely due to the challenges presented by their small scale. There is currently no method to dynamically control flies' access to food. In rodents, protocols that use dynamic food delivery are a central element of experimental paradigms that date back to the influential work of Skinner. This method is still commonly used in the analysis of learning, memory, addiction, feeding, and many other subjects in experimental psychology. The difficulty of microscale food delivery means this is not a technique used in fly behavior. In the present manuscript we describe a microfluidic chip integrated with machine vision and automation to dynamically control defined liquid food presentations and sensory stimuli. Strikingly, repeated presentations of food at a fixed location produced improvements in path efficiency during food approach. This shows that improved path choice is a learned behavior. Active control of food availability using this microfluidic system is a valuable addition to the methods currently available for the analysis of learned feeding behavior in flies.

The aim of this study was to characterize the binding profile as well as to notify the interaction of palmitic acid with metoprolol succinate at its binding site on albumin. The binding of metoprolol succinate to bovine serum albumin (BSA) was studied by equilibrium dialysis method (ED) at 27°C and pH 7.4, in order to have an insight in the binding chemistry of the drug to BSA in presence and absence of palmitic acid. The study was carried out using ranitidine as site-1 and diazepam as site-2 specific probe. Different analysis of binding of metoprolol succinate to bovine serum albumin suggested two sets of association constants: high affinity association constant (k1 = 11.0 x 10(5) M(-1)) with low capacity (n1 = 2) and low affinity association (k2 = 4.0×10(5) M(-1)) constant with high capacity (n2 = 8) at pH 7.4 and 27°C. During concurrent administration of palmitic acid and metoprolol succinate in presence or absence of ranitidine or diazepam, it was found that palmitic acid displa...

To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh.Molasses were collected from open markets in different parts of Bangladesh. The presence of hydrose in selected molasses was detected using commercial kit. To evaluate the toxic effect of hydrose, Swiss albino male mice were divided into four groups. Group I was used as control, while Groups II, III and IV received hydrose mixing food (5, 10 and 25 g/kg food), respectively, and these supplementations were continued to the end of the study (16 weeks). Blood was collected from thoracic arteries of the mice under ether anesthesia and then organs were taken. To determine the effect of hydrose on host, blood indices related to liver, heart and kidney dysfunctions were measured.Creatinine and urea levels were significantly (P<0.05) increased in a dose dependent manner in hydrose treated mice, whereas calcium level was significantly decreased in hydrose exposed mice compared to control mice. Histological study of kidney showed the glomeruler inflammation, increased diameter of renal glomeruli and enlargement of proximal tubular lumen of kidneys of mice exposed to hydrose compared to that of control animals.The results of this study indicated that use of hydrose in molasses and other food preparations in Bangladesh may cause kidney impairment.

Exposure to arsenic and subsequent development of atherosclerosis has been suggested to be responsible for increased mortality. However, biochemical events for arsenic exposue-related atherosclerosis remain unknown. This study was aimed at investigating the associations of circulating biomarkers for atherosclerosis with arsenic exposure in the individuals exposed to arsenic in Bangladesh. A total of 324 study subjects from arsenicendemic and non-endemic areas in Bangladesh were recruited. Total cholesterol, LDL and HDL levels were lower in arsenic-endemic subjects than in non-endemic subjects. Oxidized LDL, CRP, ICAM- 1 and VCAM-1 levels were significantly higher in arsenic-endemic subjects than in non-endemic subjects. These circulating molecules also showed significant correlations with arsenic exposure metrics. Further, HDL, oxidized LDL and CRP showed dose-response relationships with arsenic exposure. All these associations may be the major features of arsenic-related atheroscle...

The aim of this study was to evaluate the protective effect of Zingiber zerumbet Linn powder on sodium arsenite-induced changes of blood indices in experimental mice. Swiss albino male mice were divided into four groups. The first group was used as control, while the second, third and fourth groups were treated with Z. zerumbet (L.) powder, sodium arsenite and Z. zerumbet (L.) powder plus sodium arsenite, respectively. Animals (third and fourth groups) were exposed to sodium arsenite at a dose of 10 mg/kg body weight/day for 12 weeks. Exposure to sodium arsenite revealed a significant (p &lt; 0.05) increase of serum urea, uric acid, triglyceride (TG), glucose levels and alkaline phosphatase (ALP) activity. Serum butyryl cholinesterase (BChE) activity significantly (p &lt; 0.05) decreased in sodium arsenite-treated group as compared with control group. Interestingly, food supplemented with Z. zerumbet (L.) (50 mg/kg body weight/day) showed protective effect against sodium arsenite-in...

The precise placement of molecular and nanoparticle species at predetermined locations on a substrate surface remains a current challenge. Some barriers are particularly relevant to soft matter such as biomolecules. The advent of DNA Origami, invented by Rothemund, provides partial solutions to some challenges while raising new challenges. In this paper, two particular levels of molecular placement will be discussed,

Here we report efforts towards fabrication of DNA based nanosensors, where DNA molecules were immobilized on gold-dot arrays. AFM was used as the main characterization tool. Two major challenges associated with characterizing these nanosensors are: 1) constructing small (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;10 nm high) attachment sites on a flat surface to resolve the details of the hybridized DNA lattice and 2) fabricating attachment

Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh. A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects&#39; hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) ...

Arsenic exposure is associated with cancer and vascular diseases. Angiogenesis is an important step for the pathological development of cancer and vascular diseases. Vascular endothelial growth factor (VEGF) is a specific marker for angiogenesis. However, human study showing the association between arsenic exposure and serum VEGF levels has not yet been documented. This study was aimed to investigate the association between arsenic exposure and serum VEGF levels in the arsenic-endemic individuals in Bangladesh. A total of 260 individuals were recruited for this study. Arsenic exposure levels were measured by ICP-MS and VEGF levels were quantified using VEGF immunoassay kit. The study subjects were stratified into tertile (low, medium and high) groups based on the arsenic in water, hair and nails. Serum VEGF levels were correlated with water (rs = 0.363, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001), hair (rs = 0.205, p…

Abstract The development of strategies for the robust attachment of organized patterns of nanostructures to a variety of surfaces has been a major objective of this laboratory. One of the significant impediments to single molecule, as opposed to multiple molecule, ...

Abstract—This paper proposes and implements a low cost object tracking system using GPS and GPRS. The system allows a user to view the present and the past positions recorded of a target object on Google Map through the internet. The system reads the current position of ...

A Scanning tunneling microscope (STM) provides structural and electronic information of molecules adsorbed onto a surface with atomic resolution [1]-[3]. Features of DNA and bases (Adenine, Guanine, Thymine and Cytosine) on surfaces obtained by the STM are of great interest for ...

Bangladesh is an emerging country, it has grate prospect to development towards increasing the demand of energy .Now a day, Bangladesh is facing energy crisis. In Bangladesh, around 70% of people having lack accesses to electricity and most of them are living in the village. Among them about 40% of them are living in below poverty line. On the other hand climate change puts addition threats to development. Like the rest of the countries of the world, the demand for power is increasing day by day in our country. At present, power failure has become a severe problem for this country. It has become hard to solve the power crisis. There are several reasons behind this problem such as limitation of resources, low generation capacity, high demand, de-rated capacity of power station machineries, poor management, poor distribution line etc. To become a developed country, Bangladesh needs to overcome the problem of power crisis soon. To fight these situations, Renewable energy can be a great source to solve the power crisis problem at a great extent. Here we have discussed about different forms of renewable energy that we can use to meet the increasing power demand of Bangladesh. We have mainly discussed those renewable energy sources which can be used in solving the power crisis and sustainable development of Bangladesh such as Solar energy, Bioenergy, Geothermal, Wind energy, Micro Hydro, Ocean wave energy and Tidal energy. This paper explores the prospect, trend, utilization and its technology as well as reviews the policy and institutions and opportunities of renewable energy technology on the way to sustainable development of Bangladesh.