DNA bending,is important,for the packaging,of genetic material, regulation of gene expression and inter- action of nucleic acids with proteins. Consequently, it is of considerable,interest to quantify,the energetic factors that must,be...
moreDNA bending,is important,for the packaging,of genetic material, regulation of gene expression and inter- action of nucleic acids with proteins. Consequently, it is of considerable,interest to quantify,the energetic factors that must,be overcome,to induce,bending,of DNA, such as base stacking and phosphate– phosphate repulsions. In the present work, the elec- trostatic,contribution,of,phosphate–phosphate repulsions,to the free energy,of bending,DNA is examined,for 71 bp,linear,and,bent-form,model structures. The