Biochemical Evolution of a Potent Target of Mosquito Larvicide, 3-Hydroxykynurenine Transaminase

Biochemical Evolution of a Potent Target of Mosquito Larvicide, 3-Hydroxykynurenine Transaminase

A specific mosquito enzyme, 3-hydroxykynurenine transaminase (HKT), is involved in the processing of toxic metabolic intermediates of the tryptophan metabolic pathway. The HKT enzymatic product, xanthurenic acid, is required for <i>Plasmodium</i> spp. development in the mosquito vectors....

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Bibliographic Details
Main Authors: Huaqing Chen, Biswajit Bhowmick, Yu Tang, Jesus Lozano-Fernandez, Qian Han
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
molecular docking
in silico methods
molecular evolution
3-hydroxykynurenine transaminase
alanine glyoxylate transaminase
Online Access:https://www.mdpi.com/1420-3049/27/15/4929

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https://www.mdpi.com/1420-3049/27/15/4929

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