Abstract
Left ventricular assist devices (LVADs) assist cardiac function by regulating pump speed to support blood circulation. Traditional models of the heart and LVADs often rely on static equivalent circuit representations. However, the dynamic nature of physiological parameters across different human body states can lead to suboptimal outcomes with constant speed control strategies. This paper presents a novel approach to address this challenge by proposing dynamic circuit models for both the heart and LVADs. Leveraging Long Short-Term Memory (LSTM) neural networks trained on historical data of human blood pressure and blood flow, our method captures intricate patterns in individual physiological states. Simulation results demonstrate the efficacy of the proposed algorithm in accurately representing various states, such as non-suction and suction. The results show that the proposed dynamic model reduced the error of the LVAD model.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Son, J., Du, D., Du, Y.: Modelling and control of a failing heart managed by a left ventricular assist device. Biocybernetics Biomed. Eng. 40(1), 559–573 (2020)
Grinstein, J., Torii, R., Bourantas, C.V., Garcia-Garcia, H.M.: Left ventricular assist device flow pattern analysis using a novel model incorporating left ventricular pulsatility. ASAIO J. 67(7), 724–732 (2021)
Fetanat, M., Stevens, M., Hayward, C., Lovell, N.H.: A physiological control system for an implantable heart pump that accommodates for interpatient and intrapatient variations. IEEE Trans. Biomed. Eng. 67(4), 1167–1175 (2019)
Fetanat, M., Stevens, M., Hayward, C., Lovell, N.H.: A sensorless control system for an implantable heart pump using a real-time deep convolutional neural network. IEEE Trans. Biomed. Eng. 68(10), 3029–3038 (2021)
Pauls, J.P., Stevens, M.C., Bartnikowski, N., Fraser, J.F., Gregory, S.D., Tansley, G.: Evaluation of physiological control systems for rotary left ventricular assist devices: an in-vitro study. Ann. Biomed. Eng. 44, 2377–2387 (2016)
Xiong, S., Hou, Z.: Model-free adaptive control for unknown mimo nonaffine nonlinear discrete-time systems with experimental validation. IEEE Trans. Neural Netw. Learn. Syst. 33(4), 1727–1739 (2020)
Noly, P.E., et al.: Continuous-flow left ventricular assist devices and valvular heart disease: a comprehensive review. Can. J. Cardiol. 36(2), 244–260 (2020)
Liang, L., et al.: A flow sensor-based suction-index control strategy for rotary left ventricular assist devices. Sensors 21(20), 6890 (2021)
Blessing, K., Fink, A., Gorski, K., Wetzler, E., Patterson, J., Blaha, C.: A tale of two LVADs: a case study examining multidisciplinary rehabilitation management following LVAD/RVAD. Arch. Phys. Med. Rehabil. 104(3), e9 (2023)
Silva, L.F., Cordeiro, T.D., Lima, A.M.: A variable gain physiological controllerfor a rotary left ventricular assist device. In: 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), pp. 5606–5609. IEEE (2021)
Nag, S., Gollapudi, S.K., Del Rio, C.L., Spudich, J.A., McDowell, R.: Mavacamten,a precision medicine for hypertrophic cardiomyopathy: from a motor protein to patients. Sci. Adv. 9(30), eabo7622 (2023)
Egbe, A.C., Qureshi, M.Y., Connolly, H.M.: Determinants of left ventricular diastolic function and exertional symptoms in adults with coarctation of aorta. Circ. Heart Failure 13(2), e006651 (2020)
Zhang, L., Bhatti, M.M., Marin, M., S. Mekheimer, K.: Entropy analysis on theblood flow through anisotropically tapered arteries filled with magnetic zinc-oxide (ZnO) nanoparticles. Entropy 22(10), 1070 (2020)
Saadatnejad, S., Oveisi, M., Hashemi, M.: LSTM-based ECG classification for continuous monitoring on personal wearable devices. IEEE J. Biomed. Health Inform. 24(2), 515–523 (2019)
Petmezas, G., et al.: Automated atrial fibrillation detection using a hybrid CNN-LSTM network on imbalanced ECG datasets. Biomed. Signal Process. Control 63, 102194 (2021)
ElMoaqet, H., Eid, M., Glos, M., Ryalat, M., Penzel, T.: Deep recurrent neural networks for automatic detection of sleep apnea from single channel respiration signals. Sensors 20(18), 5037 (2020)
Ashry, S., Elbasiony, R., Gomaa, W.: An LSTM-based descriptor for human activitiesrecognition using IMU sensors. In: Proceedings of the 15th International Conference on Informatics in Control, Automation and Robotics, ICINCO, vol. 1, pp. 494–501 (2018)
Hochreiter, S., Schmidhuber, J.: Long short-term memory. Neural Comput. 9(8), 1735–1780 (1997)
Acknowledgments
This research was funded by the Open Project of National Engineering Research Center of Advanced Network Technologies (No. ANT2023003), Youth Innovation Promotion Association of the Chinese Academy of Sciences, (Y2021062); and the Science and Technology Program of Liaoning Province, (2023JH3/10200006).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Tan, A., Mu, Y., Yu, W., Liang, C., Chen, Y. (2024). A Dynamic Model of Multi-state LVAD Based on LSTM Neural Network. In: Huang, DS., Zhang, X., Zhang, C. (eds) Advanced Intelligent Computing Technology and Applications. ICIC 2024. Lecture Notes in Computer Science(), vol 14879. Springer, Singapore. https://doi.org/10.1007/978-981-97-5675-9_18
Download citation
DOI: https://doi.org/10.1007/978-981-97-5675-9_18
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-97-5674-2
Online ISBN: 978-981-97-5675-9
eBook Packages: Computer ScienceComputer Science (R0)