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Announcements
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Multimorbidity Collection
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Progress towards the Sustainable Development Goals
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Senescent stromal fibroblasts in bladder tumors support cancer progression
Aging is associated with biological processes (such as the accumulation of senescent cells) that are relevant to the development of cancer. Using genetically modified mouse models, we discovered that p16high senescent cells with a secretory phenotype accumulate in the bladder during aging, which leads to cancer progression.
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Multimorbidity
This joint collection welcomes clinical, epidemiological, and public health research focused on multimorbidity.