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Open AccessSpeg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads
Here we show that striated muscle preferentially expressed protein kinase α (Spegα) maintains cardiac function in hearts with Spegβ deficiency. Speg is required for stability of excitation-contraction coupling...
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Open AccessVariants in ASPH cause exertional heat illness and are associated with malignant hyperthermia susceptibility
Exertional heat illness (EHI) and malignant hyperthermia (MH) are life threatening conditions associated with muscle breakdown in the setting of triggering factors including volatile anesthetics, exercise, and...
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Open AccessPrinciple of restoration ecology reflected in the process creating the National Institute of Ecology
The creation of the National Institute of Ecology began as a national alternative project to preserve mudflats instead of constructing the industrial complexes by reclamation, and achieve regional development....
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Reply to: On the measured dielectric constant of amorphous boron nitride
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Open AccessAn Accurate Numerical Model Simulating Hysteretic Behavior of Reinforced Concrete Columns Irrespective of Types of Loading Protocols
In older reinforced concrete (RC) buildings, columns are fragile elements that can induce collapse of entire buildings during earthquakes. An accurate assessment of the seismic vulnerability of RC buildings us...
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Deduction of a meteorological phenology indicator from reconstructed MODIS LST imagery
Phenology is a valuable attribute of vegetation to assess the biological impacts from climate change. A challenge of phenological research is to obtain information on both high temporal resolution and fine spa...
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Open AccessAdaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation
Mutations in the skeletal muscle Ca2+ release channel, the type 1 ryanodine receptor (RYR1), cause malignant hyperthermia susceptibility (MHS) and a life-threatening sensitivity to heat, which is most severe in c...
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Ultralow-dielectric-constant amorphous boron nitride
Decrease in processing speed due to increased resistance and capacitance delay is a major obstacle for the down-scaling of electronics1–3. Minimizing the dimensions of interconnects (metal wires that connect diff...
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Abnormal shoot growth in Korean red pine as a response to microclimate changes due to urbanization in Korea
Impacts of climate change (e.g., abnormal growth in plants, early flowering, and shifting vegetation zones) are being detected throughout the world. Urban land use and its resulting microclimates work in conju...
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Fragility functions of different groups of diagonally reinforced concrete coupling beams (DRCBs)
Diagonally reinforced concrete coupling beams (DRCBs) act as a fuse element that dissipates most of the seismic energies imparted to coupled shear wall systems during earthquakes. The objective of this study i...
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Open AccessSpatial distribution of vegetation along the environmental gradient on the coastal cliff and plateau of Janggi peninsula (Homigot), southeastern Korea
Cliffs are a major plant habitat around the coastal area, but in contrast to sand dunes and salt marshes, they have been little investigated in Korea. There are simple descriptions of cliff vegetation in studi...
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Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is not fully understood. Defects in skin barrier function and dysregulation of the Th2 immune response are thought to be pivotal in AD pathoge...
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Regeneration of pitch pine (Pinus rigida) stands inhibited by fire suppression in Albany Pine Bush Preserve, New York
The Pine Barrens in New York State are dominated by pitch pine (Pinus ridgida) and scrub oaks (Quercus ilicifolia and Q. prinoides). With fire suppression over the last 90 years or so, P. rigida regeneration has ...
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Early recovery process and restoration planning of burned pine forests in central eastern Korea
In central eastern Korea, there has been a continued effort to sustain pine forests because of their value for wood and mushroom production, as well as for other resources. Through the analysis of previously b...
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Computationally Efficient and Accurate Simulation of Cyclic Behavior for Rectangular HSS Braces
During earthquakes, braces behave in complex manners because of the asymmetric response nature of their responses in tension and compression. Hollow structural sections (HSS) have been popularly used for brace...
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Open AccessGenetic variation and structure of Juniperus chinensis L. (Cupressaceae) in Korea
Juniperus chinensis L. populations are distributed locally on several areas including coastal cliffs which are difficult to access in the central eastern Korea. Wild populations inhabit relatively barren environm...
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Open AccessFloristic composition and species richness of soil seed bank in three abandoned rice paddies along a seral gradient in Gwangneung Forest Biosphere Reserve, South Korea
We sought to understand the relationship between the seed bank and vegetation in abandoned rice paddies in South Korea, in order to guide management of these sites. We investigated the floristic composition an...
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Open AccessControl of protein degradation by N-terminal acetylation and the N-end rule pathway
Nα-terminal acetylation (Nt-acetylation) occurs very frequently and is found in most proteins in eukaryotes. Despite the pervasiveness and universality of Nt-acetylation, its general functions in terms of phys...
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Do TRPV1 antagonists increase the risk for skin tumourigenesis? A collaborative in vitro and in vivo assessment
A recent hypothesis suggesting that the pharmacological target TRPV1 (transient receptor potential vanilloid subfamily, member 1) may function as a tumour suppressor, which potentially impacts the development ...
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Preface to the special issue