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Open AccessMutant mice with rod-specific VPS35 deletion exhibit retinal α-synuclein pathology-associated degeneration
Vacuolar protein sorting 35 (VPS35), the core component of the retromer complex which regulates endosomal trafficking, is genetically linked with Parkinson’s disease (PD). Impaired vision is a common non-motor...
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Article
Intermittent fasting alleviates IMQ-induced psoriasis-like dermatitis via reduced γδT17 and monocytes in mice
Psoriasis is a chronic immune mediated inflammatory skin disease with systemic manifestations. It has been reported that caloric restriction could improve severity of psoriasis patients. However, the mechanism...
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Article
Molecule-based vertical transistor via intermolecular charge transport through π-π stacking
The π-π stacking is a well-recognized intermolecular interaction that is responsible for the construction of electron hopping channels in numerous conducting frameworks/aggregates. However, the exact role of π...
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Barrier Lyapunov Function-Based Finite-Time Dynamic Surface Control for Output-Constrained Nonstrict-Feedback Systems
This paper investigates a finite-time tracking problem for the uncertainty nonlinear systems in nonstrict-feedback form, in which the output signal is restricted in a region. Based on the barrier Lyapunov func...
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Environmental collaborative governance of urban agglomeration in China: influencing factors and drivers
This study attempts to examine how urban agglomerations establish sustainable environmental collaborative governance. To achieve this goal, the qualitative comparative analysis method is used to explore the co...
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Article
Study on the Effectiveness and Mechanism of Mercapto-Modified Attapulgite for Remediation of Cadmium-Contaminated Paddy Soil
Aim of this work was to synthesize mercapto-modified attapulgite (ATP-SH) and explore the effectiveness and mechanism of ATP-SH on the remediation of Cd-contaminated soil. The ATP-SH was applied to the remedia...
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Article
Correction to: ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway
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Article
Open AccessRetinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly. Dry AMD has unclear etiology and no treatment. Lipid-rich drusen are the hallmark of dry AMD. An AMD mouse model and ...
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Article
Qingbo, a common cyprinid fish, responds diversely in behavior and locomotion to predators with different hunting modes
Almost all prey live in habitats with predators with different hunting modes; however, most studies on predation have investigated the effects of only one predator at a time. In this study, we aimed to investi...
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Article
Treatment of Donor-derived Carbapenem-resistant Klebsiella pneumoniae Infection after Renal Transplantation with Tigecycline and Extended-infusion Meropenem
Donor-derived carbapenem-resistant Klebsiella pneumoniae (CRKP) infection has recently emerged as a critical early complication after renal transplantation. Although CRKP is usually sensitive to tigecycline, mono...
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Article
Open AccessSynaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding
Adhesion G protein-coupled receptors (aGPCR) are characterized by a large extracellular region containing a conserved GPCR-autoproteolysis-inducing (GAIN) domain. Despite their relevance to several disease con...
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Article
ERCC6L that is up-regulated in high grade of renal cell carcinoma enhances cell viability in vitro and promotes tumor growth in vivo potentially through modulating MAPK signalling pathway
Renal cell carcinoma (RCC), which is one of the most diagnosed urological malignancies worldwide, is usually associated with abnormality in both genetic and cellular processes. In the present study, through an...
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Article
Effects of acclimation temperature on the thermal tolerance, hypoxia tolerance and swimming performance of two endangered fish species in China
Temperature is one of the most important environmental factors affecting the physiological activities and, thus, the fitness of fish, and physiological studies can help predict the effects of climate change on...
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Article
Open AccessPAGE4 promotes prostate cancer cells survive under oxidative stress through modulating MAPK/JNK/ERK pathway
Prostate cancer (PCa) is one of the most common cancers in male worldwide. Oxidative stress has been recognized as one of the driving signals pathologically linked to PCa progression. Nevertheless, the associa...
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Article
Information Needs and Communication Gaps between Citizens and Local Governments Online during Natural Disasters
A growing number of citizens and local governments are using tweets to communicate during natural disasters. A good understanding of the communication contents and behaviors is critical for disaster relief. Pr...
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Article
Research on oil film-assisted wire electrochemical discharge machining
Wire electrochemical discharge machining (WECDM) has the potential for cutting insulating materials. In order to achieve electrochemical discharges, WECDM is usually conducted on horizontal wire setup. It make...
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Article
Correction to: Molecular characterization of a genetically divergent equine pegivirus strain identified in China
Unfortunately, the corresponding author name was incorrectly published in the original article and the same is corrected here. The original article was corrected.
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Article
Molecular characterization of a genetically divergent equine pegivirus strain identified in China
Equine pegivirus (EPgV) is a newly discovered equine virus, which is taxonomically classified in the Pegivirus genus of the Flaviviridae family. Until now, only the complete genome sequence of the first reported ...
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Article
Correction to: Study of Flow Characteristics of ASP Solution Based on Numerical Simulation in Jet Nozzle Channel
The second author’s affiliation should read Key Laboratory of Enhanced Oil & Gas Recovery under Ministry of Education, Northeast Petroleum University, Daqing, China
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Article
Study of Flow Characteristics of ASP Solution Based on Numerical Simulation in Jet Nozzle Channel
With increasing depth of oilfield development, sublayers are becoming the main object of 0o9alkali-surfactant-polymer (ASP) flooding. Compared with major layers, sublayers differ in permeability, which may cau...