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Open AccessGestational exposure to environmental chemicals and epigenetic alterations in the placenta and cord blood mononuclear cells
Exposure to environmental chemicals such as phthalates, phenols, and polycyclic aromatic hydrocarbons (PAHs) during pregnancy can increase the risk of adverse newborn outcomes. We explored the associations bet...
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Article
Maternal and newborn metabolomic changes associated with urinary polycyclic aromatic hydrocarbon metabolite concentrations at delivery: an untargeted approach
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with adverse human health outcomes. To explore the plausible associations between maternal PAH exposure and maternal/newborn met...
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Article
Effect of Modifiable Risk Factors on Preterm Birth: A Population Based-Cohort
Objectives The purpose of this study is to evaluate the prevalence, impact, and interaction of short interpregnancy interval (IPI), pre-pregnancy body mass index (BMI) category, and pregn...
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Article
Racial Differences in the Influence of Interpregnancy Interval on Fetal Growth
Objectives Assess the influence of maternal race on the association between interpregnancy interval (IPI) and risk of small for gestational age (SGA) and large for gestational age (LGA) b...
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Article
Open AccessAssessment of DHA on reducing early preterm birth: the ADORE randomized controlled trial protocol
Preterm birth contributes to 0.5 million deliveries in the United States (one of eight pregnancies) and poses a huge burden on public health with costs in the billions. Of particular concern is that the rate o...
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Article
Open AccessSystems biology evaluation of cell-free amniotic fluid transcriptome of term and preterm infants to detect fetal maturity
Amniotic fluid (AF) is a proximal fluid to the fetus containing higher amounts of cell-free fetal RNA/DNA than maternal serum, thereby making it a promising source for identifying novel biomarkers that predict...
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Article
Open AccessPrimate-specific evolution of noncoding element insertion into PLA2G4Cand human preterm birth
The onset of birth in humans, like other apes, differs from non-primate mammals in its endocrine physiology. We hypothesize that higher primate-specific gene evolution may lead to these differences and target ...
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Article
Open AccessArea-level poverty and preterm birth risk: A population-based multilevel analysis
Preterm birth is a complex disease with etiologic influences from a variety of social, environmental, hormonal, genetic, and other factors. The purpose of this study was to utilize a large population-based bir...
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Article
Open AccessA population-based study of race-specific risk for placental abruption
Efforts to elucidate risk factors for placental abruption are imperative due to the severity of complications it produces for both mother and fetus, and its contribution to preterm birth. Ethnicity-based diffe...