1,152 Result(s)
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Chapter and Conference Paper
Dual-View Dual-Boundary Dual U-Nets for Multiscale Segmentation of Oral CBCT Images
The segmentation of teeth and root canals in oral Cone Beam Computed Tomography (CBCT) images provides crucial diagnostic value for diseases. However, existing methods have not effectively addressed the challe...
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Article
Investigating the mechanism of Lactobacillus reuteri FLRE589 on the growth and cultivation of silkworms(Bombyx mori )
The primary objective of this article is to investigate the impact of Roy's mechanism of lactobacillus on silkworm growth. The selected strain of Lactobacillus reuteri FLRE589, was employed in the experiment. L. ...
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Article
Fully integrated multi-mode optoelectronic memristor array for diversified in-sensor computing
In-sensor computing, which integrates sensing, memory and processing functions, has shown substantial potential in artificial vision systems. However, large-scale monolithic integration of in-sensor computing ...
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Article
Uncovering embodied carbon emissions network between China and major regional economies with consideration of China’s trade structure optimization
Carbon emissions embodied in trade account for 23% of total global emissions. This phenomenon will exacerbate as global trade flourishes, impeding carbon reduction. To clarify the evolutionary characteristics ...
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Article
Reducing fluorescence interference for improved Raman spectroscopic analysis of plant cell walls
Lignin fluorescence in plant cell walls significantly interferes with Raman spectroscopic signals, resulting in compromised analytical accuracy and resolution. To address this issue, a strategy was implemented...
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Article
Distinct mutation features and its clinical significance in myelodysplastic syndromes with normal karyotype
Myelodysplastic syndromes (MDS) is a highly heterogeneous myeloid neoplastic disease, which needs personalized evaluation and therapy. To analyze the features and significance of gene mutations for MDS patient...
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Article
Population pharmacokinetics of fluconazole for prevention or treatment of invasive candidiasis in Chinese young infants
The dosing of fluconazole for young infants remains empirical because of the limited pharmacokinetic (PK) data. We aimed to establish a population PK model and assess the systematic exposure-response of common...
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Article
Astragaloside IV Improves Muscle Atrophy by Modulating the Activity of UPS and ALP via Suppressing Oxidative Stress and Inflammation in Denervated Mice
Peripheral nerve injury is common clinically and can lead to neuronal degeneration and atrophy and fibrosis of the target muscle. The molecular mechanisms of muscle atrophy induced by denervation are complex a...
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Article
Label-free detection and simultaneous viability determination of CTCs by lens-free imaging cytometry
The detection of extremely rare circulating tumor cells (CTCs) in peripheral blood and simultaneously identifying their viabilities are significant for cancer diagnosis and prognosis as well as monitoring the ...
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Article
Stretchable, self-healing, adhesive and anti-freezing ionic conductive cellulose-based hydrogels for flexible supercapacitors and sensors
Conductive hydrogels have great application potential in flexible electronic devices. Nevertheless, it is a huge challenge to fabricate multifunctional conductive hydrogels simultaneously integrated with high ...
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Article
Open AccessLa-Fe-Si magnetocaloric composite with anisotropic microstructure prepared by hot pressing
In this study, we have proposed an anisotropic microstructure in La-Fe-Si magnetocaloric composites for thermal management. This is vital to the rapid heat exchange and high working efficiency in magnetic refr...
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Article
Open AccessPrivacy enhancing and generalizable deep learning with synthetic data for mediastinal neoplasm diagnosis
The success of deep learning (DL) relies heavily on training data from which DL models encapsulate information. Consequently, the development and deployment of DL models expose data to potential privacy breach...
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Article
Open AccessThe role of biophysical cues and their modulated exosomes in dental diseases: from mechanism to therapy
Dental diseases such as caries and periodontitis have been common public health problems. Dental disease treatment can be achieved through stem cell-based dental regeneration. Biophysical cues determine the fa...
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Article
Open AccessEndothelial cells derived extracellular vesicles promote diabetic arterial calcification via circ_0008362/miR-1251-5p/Runx2 axial
Arterial calcification, an independent predictor of cardiovascular events, increases morbidity and mortality in patients with diabetes mellitus (DM), but its mechanisms remain unclear. Extracellular vesicles (...
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Article
Open AccessCardiomyocyte-specific knockout of ADAM17 alleviates doxorubicin-induced cardiomyopathy via inhibiting TNFα–TRAF3–TAK1–MAPK axis
The pathogenesis of doxorubicin-induced cardiomyopathy remains unclear. This study was carried out to test our hypothesis that ADAM17 aggravates cardiomyocyte apoptosis induced by doxorubicin and inhibition of...
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Article
The role of lipoprotein‑associated phospholipase A2 in inflammatory response and macrophage infiltration in sepsis and the regulatory mechanisms
Lipoproteinassociated phospholipase A2 (Lp-PLA2), encoded by the phospholipase A2 group VII (Pla2g7) gene, has been pertinent to inflammatory responses. This study investigates the correlation between Lp-PLA2 and...
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Article
Open AccessIntratumoral microbiota as a novel prognostic indicator in bladder cancer
Microbes are important components of the tumor microenvironment and have a close relationship with tumors. However, there is still a lack of research on the intratumoral microbiota in bladder cancer and its im...
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Article
Open AccessToward long-term and high-precision multimodal intracranial biomarker monitoring
Long-term and high-precision intracranial biomarker monitoring is crucial for the diagnosis, prevention, and prognosis of various diseases. However, existing technologies are associated with several issues of ...
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Article
Open AccessQin-Yu-Qing-Chang decoction reshapes colonic metabolism by activating PPAR-γ signaling to inhibit facultative anaerobes against DSS-induced colitis
Qin-Yu-Qing-Chang decoction (QYQC), an herbal formula from China, is extensively employed to manage ulcerative colitis (UC) and exhibits potential benefits for colonic function. Nevertheless, the fundamental m...
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Article
Enhanced plasmonic scattering imaging via deep learning–based super-resolution reconstruction for exosome imaging
Exosome analysis plays pivotal roles in various physiological and pathological processes. Plasmonic scattering microscopy (PSM) has proven to be an excellent label-free imaging platform for exosome detection. ...