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Open AccessPreoperative prediction of MGMT promoter methylation in glioblastoma based on multiregional and multi-sequence MRI radiomics analysis
O6-methylguanine-DNA methyltransferase (MGMT) has been demonstrated to be an important prognostic and predictive marker in glioblastoma (GBM). To establish a reliable radiomics model based on MRI data to predi...
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Article
Magnetically circular layered triboelectric nanogenerators by advanced self-sensing composites
This paper provides a numerical simulation study of Magnetically Circular Layers of Triboelectric Nanogenerators (MCL-TENGs) for energy harvesting and self-powered sensing. The MCL-TENGs generate electrical en...
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Article
Application of 5T glutamate chemical exchange saturation transfer imaging in brain tumors: preliminary results
Glutamate chemical exchange saturation transfer (GluCEST) is a non-invasive CEST imaging technique for detecting glutamate levels in tissues. We aimed to investigate the reproducibility of the 5T GluCEST techn...
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Article
Open AccessEstimation methods of wetland carbon sink and factors influencing wetland carbon cycle: a review
In the global ecosystem, wetlands are vital carbon sinks, playing a crucial role in absorbing greenhouse gases such as carbon dioxide and mitigating global warming. Accurate estimation of wetland carbon conten...
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Article
Open AccessThe feasibility of half-dose contrast-enhanced scanning of brain tumours at 5.0 T: a preliminary study
This study investigated and compared the effects of Gd enhancement on brain tumours with a half-dose of contrast medium at 5.0 T and with a full dose at 3.0 T.
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Quantifying H&E staining results, grading and predicting IDH mutation status of gliomas using hybrid multi-dimensional MRI
To assess the performance of hybrid multi-dimensional magnetic resonance imaging (HM-MRI) in quantifying hematoxylin and eosin (H&E) staining results, grading and predicting isocitrate dehydrogenase (IDH) muta...
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Article
Gripper vibration analysis of inspection robot during variable working flight of pre-landing on high-voltage transmission line
When the high-voltage transmission line inspection robot (HVTIR) with gripper is pre-landing line during flight, the vibration of the landing gripper seriously affects the stability of landing line. To study t...
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Article
Hemispheric coupling between structural and functional asymmetries in clinically asymptomatic carotid stenosis with cognitive impairment
Advanced carotid stenosis is a known risk factor for ischemic stroke and vascular dementia, and it is associated with multidomain cognitive impairment as well as asymmetric alterations in hemispheric structure...
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Article
Open AccessMcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling
While canonical Wnt signaling is well recognized for its crucial regulatory functions in cell fate decisions, the role of non-canonical Wnt signaling in adult stem cells remains elusive and contradictory. Here...
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Article
Open AccessCT-based deep learning model: a novel approach to the preoperative staging in patients with peritoneal metastasis
Peritoneal metastasis (PM) is a frequent manifestation of advanced abdominal malignancies. Accurately assessing the extent of PM before surgery is essential for patients to receive optimal treatment. Therefore...
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Article
Functional abnormalities of the cerebellum in vascular mild cognitive impairment
The alterations in cerebellar activity that occur in vascular mild cognitive impairment remain largely unexplored. This study aimed to investigate potential associations between abnormal cerebellar functional ...
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Article
Azithromycin inhibits glioblastoma angiogenesis in mice via inducing mitochondrial dysfunction and oxidative stress
The poor outcomes in glioblastoma (GBM) necessitate new treatments. As GBM is highly vascularized and its growth is largely dependent on angiogenesis, angiogenesis inhibitors have been hotly evaluated in clini...
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Article
Activation of Ventral Pallidum CaMKIIa-Expressing Neurons Promotes Wakefulness
The ventral pallidum (VP) is involved in the regulation of a variety of behaviors such as motor, reward, and behavioral motivation, and the ability to perform these functions properly is dependent on a high de...
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CaMKIIa Neurons of the Ventromedial Hypothalamus Mediate Wakefulness and Anxiety-like Behavior
Insomnia and anxiety are two common and closely related clinical problems that pose a threat to individuals’ physical and mental well-being. There is a possibility that some nuclei and neural circuits in the b...
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Article
Open AccessStability and repeatability of diffusion-weighted imaging (DWI) of normal pancreas on 5.0 Tesla magnetic resonance imaging (MRI)
To explore the stability and repeatability of diffusion-weighted imaging (DWI) of normal pancreas with different field of views (FOV) on 5.0 T magnetic resonance imaging (MRI) system. Twenty healthy subjects u...
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Article
Physicochemical and compressibility characteristics of dispersive clay under freeze–thaw cycles and soaking in northeastern China
Dispersive clay is a special soil, and the clay particles are easily dissolved in low-salinity water. In northeastern China, frost-heave cracks and subsidence have formed in the dispersive clay subgrades of ne...
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Article
Open AccessDual signal amplification coupling with DNA-templated silver nanoclusters for sensitive and label-free detection of thrombin
Sensitive and reliable determination of thrombin is relevant in the realms of medical and biological research as it serves as an essential biomarker of a number of blood-related illnesses. Herein, we integrate...
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Article
The resting-state topological organization damage of language-related brain regions in post-stroke cognitive impairment
The topology of brain networks is the foundation of cognition. We hypothesized that stroke damaged topological organization resulting in cognitive impairment. The aim was to explore the damage pattern of the r...
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Article
Open AccessWnt signaling in colorectal cancer: pathogenic role and therapeutic target
The Wnt signaling pathway is a complex network of protein interactions that functions most commonly in embryonic development and cancer, but is also involved in normal physiological processes in adults. The ca...
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Article
Dry passivation of austenitic SUS 301L stainless steel against pitting corrosion in marine atmospheric environment
Being an exclusive construction material for lightweight rail vehicles, protection from pitting corrosion in harsh marine atmospheric environment in high humidity and Cl− ion concentration is critical for austeni...