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951 Result(s)
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Article
Effect of Glass Tube Suction Casting on Solidification Process and Si Refinement of Hypereutectic Al–Si Alloy
This study unpicks the influence of the glass tube suction casting (GTSC) with different inner diameters (8, 10, 12 and 14 mm) on the solidification process of the hypereutectic Al–Si alloy (A390) and dissects...
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Open AccessIdentification of lysine lactylation (kla)-related lncRNA signatures using XGBoost to predict prognosis and immune microenvironment in breast cancer patients
Breast cancer (BC) stands as a predominant global malignancy, significantly contributing to female mortality. Recently uncovered, histone lysine lactylation (kla) has assumed a crucial role in cancer progressi...
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Effect of Single-Pass Rolling on Microstructure and Mechanical Properties of AZ31 Alloy Processed by Equal Channel Angular Pressing
In this study, AZ31 alloys were subjected to multi-pass equal channel angular pressing (ECAP) and subsequent single-pass rolling (SPR) with increased rolling reductions. The grain structure, texture and mechan...
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Article
Exosomal GDNF from Bone Marrow Mesenchymal Stem Cells Moderates Neuropathic Pain in a Rat Model of Chronic Constriction Injury
Both of exosomes derived from mesenchymal stem cells (MSCs) and glial cell line-derived neurotrophic factor (GDNF) show potential for the treatment of neuropathic pain. Here, the analgesic effects of exosomes ...
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Article
Open AccessDietary nitrate maintains intestinal epithelia homeostasis in aged mice
The intestinal tract, which is the primary site of digestion and absorption of nutrients, is one of the most vulnerable organs during aging. Dietary nitrate, which is mainly derived from the diet and absorbed ...
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Article
Association between stigma and quality of life among chronic refractory wounds patients and informal caregivers: an actor-partner interdependence model analysis
The co-occurrence of health impairments in patients and their informal caregivers may be particularly common in intimate care settings in China. Patients with Chronic Refractory Wounds (CRWs) and their informa...
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Open AccessThe impact of integrated hepatitis B virus DNA on oncogenesis and antiviral therapy
The global burden of hepatitis B virus (HBV) infection remains high, with chronic hepatitis B (CHB) patients facing a significantly increased risk of developing cirrhosis and hepatocellular carcinoma (HCC). Th...
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Isolation of an α-glucosidase Inhibitor from Houttuynia cordata Thunb. and Its In vitro and In vivo Hypoglycemic Bioactivity
The Houttuynia cordata Thunb. belongs to the Saururaceae family and is a well-known medicine and food homologous plant. Herein, the isolation of an α-glucosidase inhibitor from Houttuynia cordata Thunb. and chara...
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Article
Open AccessSingle-cell multiomics analysis reveals cell/tissue-specific associations in bipolar disorder
This study investigates the cellular origin and tissue heterogeneity in bipolar disorder (BD) by integrating multiomics data. Four distinct datasets were employed, including single-cell RNA sequencing (scRNA-s...
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Article
Electromechanical response of fungus polysaccharide gel artificial muscle prepared from tremella fuciformis extract and carboxylated chitosan
In recent years, natural polymeric materials have been widely used in biogel artificial muscles. As a natural fungal polysaccharide material, tremella fuciformis extract (TFE) contains many hydroxyl and carbox...
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Article
Open AccessInvestigation of nutrition status and analysis of 180-day readmission factors in elderly hospitalized patients with COPD
Malnutrition is prevalent among elderly patients with COPD, who also experience a high rate of readmission. Therefore, it is imperative to investigate the nutrition status of these patients, identify risk fact...
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Open AccessMapping the molecular landscape of Lotus japonicus nodule organogenesis through spatiotemporal transcriptomics
Legumes acquire nitrogen-fixing ability by forming root nodules. Transferring this capability to more crops could reduce our reliance on nitrogen fertilizers, thereby decreasing environmental pollution and agr...
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Article
Open AccessComprehensive analysis of clinical data and radiomic features from contrast enhanced CT for differentiating benign and malignant pancreatic intraductal papillary mucinous neoplasms
The primary aim of this investigation was to leverage radiomics features derived from contrast-enhanced abdominal computed tomography (CT) scans to devise a predictive model to discern the benign and malignant...
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Article
Open AccessASM is a therapeutic target in dermatomyositis by regulating the differentiation of naive CD4 + T cells into Th17 and Treg subsets
This study aims to investigate the involvement of acid sphingomyelinase (ASM) in the pathology of dermatomyositis (DM), making it a potential therapeutic target for DM.
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Article
Deletion of Bmal1 in aggrecan-expressing cells leads to mouse temporomandibular joint osteoarthritis
Articular cartilage is the major affected tissue during the development of osteoarthritis (OA) in temporomandibular joint (TMJ). The core circadian rhythm molecule Bmal1 regulates chondrocyte proliferation, di...
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Article
Options for Dynamic Similarity of Interacting Fluids, Elastic Solids and Rigid Bodies Undergoing Large Motions
Motivated by a design of a vertical axis wind turbine, we present a theory of dynamical similarity for mechanical systems consisting of interacting elastic solids, rigid bodies and incompressible fluids. Throu...
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Article
6-mm shunt transjugular intrahepatic portosystemic shunt in patients with severe liver atrophy and variceal bleeding
We proposed a strategy for the creation of a 6-mm transjugular intrahepatic portosystemic shunt (TIPS) and to assess its effectiveness compared to a conventional 8-mm shunt for TIPS-induced hepatic encephalopa...
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Article
Effect of Room Temperature Ultrasonic Vibration Compression on the Microstructure Evolution and Mechanical Properties of AZ91 Alloy
To investigate the potential of direct ultrasonic vibration on improving the performance of magnesium alloys, this study first employed the ultrasonic vibration compression (UVC) on the solid solution treated ...
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Article
Preparation of moso bamboo columnar activated carbon with high adsorption property via polyacrylamide@asphalt adhesives and steam activation
Moso bamboo, as a kind of renewable functional material, exhibits outstanding development potential. It is promising to prepare activated carbon with good mechanical strength and high specific surface area usi...
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Article
Open AccessGenome-wide identification of the Q-type C2H2 zinc finger protein gene family and expression analysis under abiotic stress in lotus (Nelumbo nucifera G.)
Lotus (Nelumbo nucifera G.) is an important aquatic plant with high ornamental, economic, cultural and ecological values, but abiotic stresses seriously affect its growth and distribution. Q-type C2H2 zinc finger...