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Article
Open AccessRepellent effects of Chinese cinnamon oil on nymphal ticks of Haemaphysalis longicornis, Rhipicephalus haemaphysaloides, and Hyalomma asiaticum
The repellent activity of Chinese cinnamon oil (Cinnamomum cassia) on nymphal ticks (Haemaphysalis longicornis Neumann, Rhipicephalus haemaphysaloides Supino, and Hyalomma asiaticum Schulze and Schlottke) was eva...
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Article
Open AccessProteomic analysis of extracellular vesicles from tick hemolymph and uptake of extracellular vesicles by salivary glands and ovary cells
Extracellular vesicles (EVs) are a heterogeneous group of cell-derived membranous structures that are important mediators of intercellular communication. Arthropods transport nutrients, signaling molecules, wa...
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Chapter and Conference Paper
Development of No-Back Mechanism Models for Electrical THSA Based on Experimental Study
With the rapid development of power-by-wire technology applied in flight controls, electro-hydrostatic actuator (EHA) and electromechanical actuator (EMA) are preferred to the application of primary flight con...
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Article
Open AccessThe ecdysteroid receptor regulates salivary gland degeneration through apoptosis in Rhipicephalus haemaphysaloides
It is well established that ecdysteroid hormones play an important role in arthropod development and reproduction, mediated by ecdysteroid receptors. Ticks are obligate hematophagous arthropods and vectors of ...
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Article
Open AccessData from expressed sequence tags from the organs and embryos of parthenogenetic Haemaphysalis longicornis
Haemaphysalis longicornis is the most important tick species in Japan and has a wide range of vector capacity. Due to its veterinary and medical importance, this tick species has been used as a model for tick/vec...
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Article
Open AccessIdentification of the Bcl-2 and Bax homologs from Rhipicephalus haemaphysaloides and their function in the degeneration of tick salivary glands
The salivary glands of female ticks degenerate rapidly by apoptosis and autophagy after feeding. Bcl-2 family proteins play an important role in the apoptosis pathways, but the functions of these proteins in t...
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Article
Engorgement of Rhipicephalus haemaphysaloides ticks blocked by silencing a protein inhibitor of apoptosis
Inhibitors of apoptosis (IAPs) are regulators of cell death and may play a role in the salivary glands of ticks during blood-feeding. We cloned the open reading frame (ORF) sequence of the IAP gene in Rhipicephal...
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Article
Open AccessKLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy
Cardiovascular diseases have become the leading cause of death worldwide, and cardiac hypertrophy is the core mechanism underlying cardiac defect and heart failure. However, the underlying mechanisms of cardia...
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Article
A cysteine protease of Babesia microti and its interaction with tick cystatins
Babesiosis is a tick-borne protozoonosis caused by Babesia, which can cause fever, hemolytic anemia, hemoglobinuria, and even death. Babesia microti is a parasite found in rodents and can be pathogenic to humans....
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Article
Open AccessInitiator and executioner caspases in salivary gland apoptosis of Rhipicephalus haemaphysaloides
Apoptosis is fundamental in maintaining cell balance in multicellular organisms, and caspases play a crucial role in apoptosis pathways. It is reported that apoptosis plays an important role in tick salivary g...
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Article
Preparation of high-damping soft elastomer based on Eucommia ulmoides gum
This paper focus on the nature of a high-damping soft elastic material based on Eucommia ulmoides gum (EUG) obtained by epoxidation of EUG first and then in situ reaction between epoxy group and sodium bisulfite....
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Article
Molecular characterization of clathrin heavy chain (Chc) in Rhipicephalus haemaphysaloides and its effect on vitellogenin (Vg) expression via the clathrin-mediated endocytic pathway
Clathrin plays an important role in arthropods, but its function in ticks has not been explored. Here, we describe the molecular characteristics of the clathrin heavy chain of the tick Rhipicephalus haemaphysaloi...
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Article
Open AccessLocalized expression and inhibition effect of miR-184 on blood digestion and oviposition in Haemaphysalis longicornis (Acari: Ixodidae)
The hard tick Haemaphysalis longicornis (Ixodidae) is widely distributed in East Asia, China, Australia and New Zealand. It can transmit many infectious pathogens, including the causative agents of human ricketts...
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Article
Open AccessImmunomodulatory effects of Rhipicephalus haemaphysaloides serpin RHS2 on host immune responses
Rhipicephalus haemaphysaloides is a widespread tick species in China and other South East Asian countries, where it is the vector of many pathogens. The objective of this study was to study the role of serpin (se...
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Article
Molecular characterization, tissue-specific expression, and RNA knockdown of the putative heat shock cognate 70 protein from Rhipicephalus haemaphysaloides
Heat shock cognate 70-kDa protein (RH-Hsc70) was identified from a cDNA library synthesized from the sialotranscriptomes of unfed and fed Rhipicephalus haemaphysaloides. The RH-Hsc70 open reading frame is 1950 bp...
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Article
Open AccessImmunosuppressive effects of tick protein RHcyst-1 on murine bone marrow-derived dendritic cells
Ticks, as blood-feeding arthropod vectors, have evolved their own unique mechanism to suppress host immune responses and evade immune defenses in order to complete blood-feeding. The immunoregulatory effect of...
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Article
Open AccessA microRNA profile of saliva and the role of miR-375 in Haemaphysalis longicornis (Ixodida: Ixodidae)
Tick saliva contains many bioactive molecules that are involved in attachment to the host, blood-feeding and transmission of pathogens. MicroRNAs (miRNAs) are a class of short non-coding RNAs with a length of ...
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Article
Open AccessMolecular characterization of Babesia microti thioredoxin (BmTrx2) and its expression patterns induced by antiprotozoal drugs
Human babesiosis is an infectious disease that is epidemic in various regions all over the world. The predominant causative pathogen of this disease is the intra-erythrocytic parasite Babesia microti. The thiored...
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Article
Open AccessCaspase-1 participates in apoptosis of salivary glands in Rhipicephalus haemaphysaloides
Ticks are among the most harmful vectors worldwide. Their salivary glands play essential roles in blood-feeding and pathogen transmission and undergo apoptosis after feeding. Although it was previously reporte...
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Article
Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum
Kunitz/bovine pancreatic trypsin inhibitor proteins are abundant in the salivary glands of ticks and perform multiple functions in blood feeding, including inhibiting blood coagulation, regulating host blood s...