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Article
Open AccessThe lncRNA LINC01605 promotes the progression of pancreatic ductal adenocarcinoma by activating the mTOR signaling pathway
This study investigated the molecular mechanism of long intergenic non-protein coding RNA 1605 (LINC01605) in the process of tumor growth and liver metastasis of pancreatic ductal adenocarcinoma (PDAC).
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Article
The Impacts of Nirmatrelvir–Ritonavir on Myocardial Injury and Long-Term Cardiovascular Outcomes in Hospitalized Patients with COVID-19 amid the Omicron Wave of the Pandemic
Even though nirmatrelvir–ritonavir can improve the short-term morbidity and mortality in COVID-19 patients, the effects of this treatment on long-term major adverse cardiovascular events (MACEs), especially my...
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Article
Analysis of cuproptosis-related lncRNA signature for predicting prognosis and tumor immune microenvironment in pancreatic cancer
Pancreatic cancer (PC) is a highly malignant digestive tract tumor, with a dismal 5-year survival rate. Recently, cuproptosis was found to be copper-dependent cell death. This work aims to establish a cupropto...
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Article
The genomic, transcriptomic, and immunological profiles of perineural invasion in pancreatic ductal adenocarcinoma
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Chapter
Bioinspired Materials Inherited with Antimicrobial Properties for Tissue Engineering
The advancement in the preparation of biomaterials that possess tissue engineering applications has predominantly concerted on developing biomimetic materials inherited with the properties of designing new tis...
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Article
Bending Stiffness of the Floor of the Assembled-Type Light Steel-Modular House
The assembled -type light steel (ATLS) modular house is an emerging type of eco-friendly modular building and has been widely used for buildings with repetitive units. This paper focused on the bending stiffne...
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Article
A Simplified Procedure for the Structural Reinforcement Design of Hyperbolic Cooling Tower Shells
The reinforcement design is the most critical and time-consuming process in structural design of hyperbolic cooling tower (HCT) shell due to the complicate internal force distributions and arbitrary direction ...
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Article
A Comparison of Tumor-Associated and Non-Tumor-Associated Gastric Microbiota in Gastric Cancer Patients
How gastric cancer (GC) incidence is associated with changes in the gastric microbiome has not been firmly established. The present study therefore aims to investigate the microbial communities present within ...
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Article
Event-triggered Control of Positive Switched Systems with Actuator Saturation and Time-delay
This paper investigates the event-triggered control of positive switched systems with randomly occurring actuator saturation and time-delay, where the actuator saturation and time-delay obey different Bernoull...
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Article
Association between long-term prescription of febuxostat and the progression of heart failure with preserved ejection fraction in patients with hypertension and asymptomatic hyperuricemia
Both hypertension and hyperuricemia are closely associated with the morbidity and mortality of heart failure. This study was designed to evaluate the influences of long-term xanthine oxidase inhibitor (febuxos...
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Article
Modelling virgin compression line of compacted unsaturated soils
In this paper, the volumetric collapse of an unsaturated soil, upon soaking to saturation under a certain stress level, is referred to as soaking collapse. The soaking collapse for a soil under virgin conditio...
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Article
Open AccessmiR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity
Clinical therapy of doxorubicin (DOX) is limited due to its cardiotoxicity. miR-146a was proved as a protective factor in many cardiovascular diseases, but its role in chronic DOX-induced cardiotoxicity is unc...
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Article
Knockdown of TRIM32 Protects Hippocampal Neurons from Oxygen–Glucose Deprivation-Induced Injury
Tripartite motif 32 (TRIM32) is a member of TRIM family that plays a potential role in neural regeneration. However, the biological function of TRIM32 in cerebral ischemia reperfusion injury has not been inves...
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Chapter and Conference Paper
A Novel Approach for Predicting LncRNA-Disease Associations by Structural Perturbation Method
Numerous experiments have demonstrated that long non-coding RNA (lncRNA) plays an important role in various systems of the human body. The prediction of lncRNA-disease associations is conducive to the diagnosi...
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Article
Open AccessMicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma
MicroRNAs play crucial roles in tumorigenesis and tumor progression. miR-770 has been reported to be downregulated in several cancers and affects cancer cell proliferation, apoptosis, metastasis and drug resis...
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Article
Open AccessPrognostic impact of HbA1c variability on long-term outcomes in patients with heart failure and type 2 diabetes mellitus
The prognostic impact of long-term glycemic variability on clinical outcomes in patients with heart failure (HF) and type 2 diabetes mellitus (T2DM) remains unclear. We determined and compared hemoglobin A1c (...
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Chapter and Conference Paper
Constitutive Model for Soaking-Induced Volume Change of Unsaturated Compacted Expansive Soil
Several researchers have proposed models extending the independent stress state variables approach to describe the nonlinear nature of the normal consolidation line (NCL) for unsaturated soils. However, there...
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Article
Evaluation of the value of plasma concentration of copeptin in the first prenatal visit to diagnose gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is increasing worldwide. The aim of this study was to investigate whether copeptin concentrations, measured at the first prenatal visit, are associated with risk of GDM.
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Article
Open AccessHypoxia imaging in cells and tumor tissues using a highly selective fluorescent nitroreductase probe
Hypoxia is a characteristic of locally advanced solid tumors, resulting from an imbalance between oxygen consumption and supply. In hypoxic solid tumors, an increased expression of nitroreductase (NTR) is dete...
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Article
Open AccessAnti-proliferative potential of Glucosamine in renal cancer cells via inducing cell cycle arrest at G0/G1 phase
Renal cell carcinoma (RCC) is one of the most common types of cancer in urological system worldwide. Recently, the anticancer role of Glucosamine has been studied in many types of cancer. The aim of this study...