133 Result(s)
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Article
Gestational diabetes mellitus affects the differentiation of hematopoietic stem cells in neonatal umbilical cord blood
There are abundant hematopoietic stem cells (HSCs) in cord blood. It is known that HSCs continue to differentiate to CLP, CMP and erythroid progenitor cells (EPC), EPC ultimately differentiated to platelets an...
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Article
Comparative proteomic exploration of plasma proteins in different levels of vitamin D with type 2 diabetes mellitus using iTRAQ-coupled LC-MS/MS
Due to the variety of modern diet and lifestyle changes, China has become the world’s largest number of people with T2DM. How to prevent and cure T2DM has become one of the urgent public health events in China...
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Article
PDZK1 confers sensitivity to sunitinib in clear cell renal cell carcinoma by suppressing the PDGFR-β pathway
Sunitinib has emerged as the primary treatment for advanced or metastatic clear cell renal cell carcinoma (ccRCC) due to its significant improvement in patients’ average survival time. However, drug resistance...
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Article
Transcatheter Arterial Embolization with Bleomycin-Lipiodol of Hepatic Hemangiomas: Safety, Efficacy and Predictors of Response
To evaluate the safety, efficacy and predictors of response of transcatheter arterial embolization (TAE) to treat hepatic hemangiomas (HHs).
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Article
Open AccessBlocking the TRAIL-DR5 Pathway Reduces Cardiac Ischemia–Reperfusion Injury by Decreasing Neutrophil Infiltration and Neutrophil Extracellular Traps Formation
Acute myocardial infarction (AMI) is a leading cause of mortality. Neutrophils penetrate injured heart tissue during AMI or ischemia–reperfusion (I/R) injury and produce inflammatory factors, chemokines, and e...
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Article
Anti-neurofascin-155 antibody mediated a distinct phenotype of chronic inflammatory demyelinating polyradiculoneuropathy
To investigate Ranvier’s autoantibodies prevalence and isotypes in various peripheral neuropathy variants, compare clinical features between seronegative and seropositive patients, and elucidate immune mechani...
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Article
Open AccessInflammatory myofibroblastic tumor of the liver after adrenal neuroblastoma surgery: a case report
A boy aged 55 months was diagnosed with stage IV Neuroblastoma (NB) of the right adrenal gland 2 years ago. Preoperative chemotherapy was given and he was then treated with retroperitoneal tumor resection and ...
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Article
Low temperature and dark culture inhibited explant browning and promoted in vitro regeneration of Juglans mandshurica
Juglans mandshurica is an important component of Korean pine mixed and secondary forests in Northeast China and is also a precious timber and economic species. In this study, plant regeneration of J. mandshurica
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Article
Seasonal changes in gut microbiota of sea cucumber over natural aestivation cycle
Sea cucumber Apostichopus japonicus is an ideal model organism for marine invertebrate aestivation; it annually enters a “sleeping state” for nearly 3 months when ambient water temperature range is 25–30 °C. The ...
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Article
Preparation and evaluation of Thesium chinense extract loaded polyvinyl alcohol/sodium alginate hydrogel for wound healing
A novel composite hydrogel was prepared by combining polyvinyl alcohol (PVA) and sodium alginate (SA) in a specific proportion to serve as a drug carrier, and then loading the extract of Thesium chinense (TCE) on...
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Article
Open AccessHepatitis B virus reactivation in hepatocellular carcinoma patients after hepatic arterial infusion chemotherapy combined with and without immunotherapy
Hepatitis B virus (HBV) reactivation (HBVr) is a major concern for hepatocellular carcinoma (HCC) patients undergoing hepatic arterial infusion chemotherapy (HAIC) using mFOLFOX6 regimen. There is insufficient...
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Article
Open AccessANGPTL3 is a novel HDL component that regulates HDL function
Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...
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Article
Open AccessUtility and predictive value of the CRAFITY score in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus tyrosine kinase inhibitors and PD-1 inhibitor
The prognostic significance of the CRAFITY score (CRP and AFP in ImmunoTherapY) has been demonstrated in hepatocellular carcinoma (HCC) patients receiving immunotherapy. The purpose of this study was to investiga...
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Article
Fault Diagnosis of Rolling Bearings Based on the Improved Symmetrized Dot Pattern Enhanced Convolutional Neural Networks
The main purpose of this paper is to change the structure of the SDP to include more fault information. Furthermore, improve the diagnostic accuracy and anti-noise performance of the bearing fault diagnosis me...
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Article
Open AccessHotspots and trends of microglia in Alzheimer's disease: a bibliometric analysis during 2000–2022
Alzheimer's disease is one common type of dementia. Numerous studies have suggested a correlation between Alzheimer's disease and inflammation. Microglia mainly participate in the inflammatory response in the ...
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Article
Open AccessTreatment outcomes of retreated patients with isoniazid/rifampicin resistant pulmonary tuberculosis
About 8% of TB cases worldwide are estimated to have rifampicin-susceptible, isoniazid-resistant tuberculosis (Hr-TB), ranging from 5 to 11% regions. However, Hr-TB has not received much attention while compar...
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Chapter and Conference Paper
Multi-pair Contrastive Learning Based on Same-Timestamp Data Augmentation for Sequential Recommendation
The core of sequential recommendations is to model users’ dynamic preferences from their sequential historical behaviors. Bidirectional representation models can make better sequential recommendations because ...
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Article
In3+-doped Sr2Fe1.5Mo0.5O6−δ cathode with improved performance for an intermediate-temperature solid oxide fuel cell
Promoting the oxygen reduction reaction (ORR) is critical for commercialization of intermediate-temperature solid oxide fuel cells (IT-SOFCs), where Sr2Fe1.5Mo0.5O6−δ (SFM) is a promising cathode by working as a ...
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Article
Thermal-elastic field around an elliptical nano-inclusion with interface conduction and interface stress effects
We analyze the thermo-elastic behavior of an elliptical nano-inclusion incorporating interface conduction and interface stress effects when embedded in an infinite matrix under plane deformation. The effect of...
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Article
BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation and antitumor effects in preclinical models
OX40 is a costimulatory receptor that is expressed primarily on activated CD4+, CD8+, and regulatory T cells. The ligation of OX40 to its sole ligand OX40L potentiates T cell expansion, differentiation, and activ...