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Open AccessNovel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology
The cardiac action potential (AP) is vital for understanding healthy and diseased cardiac biology and drug safety testing. However, techniques for high throughput cardiac AP measurements have been limited. Her...
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Protocol
The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential
The Comprehensive In Vitro Proarrhythmia Assay (CiPA) initiative, led by the US Food and Drug Administration (FDA), aims to improve preclinical cardiac safety evaluation and reduce unwarranted drug attrition b...
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