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Article
Open AccessStorage stability of lysostaphin solution and its pulmonary delivery
Methicillin-resistant Staphylococcus aureus (MRSA) has become a leading causative pathogen of nosocomial pneumonia with an alarming in-hospital mortality rate of 30%. Last resort antibiotic, vancomycin, has been ...
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Article
Open AccessAssociation of cigarette smoking, smoking cessation with the risk of cardiometabolic multimorbidity in the UK Biobank
To investigate the association between cigarette smoking, smoking cessation and the trajectory of cardiometabolic multimorbidity (CMM), and further to examine the association of age at smoking initiation and s...
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Article
Open AccessEffect of probiotics on children with autism spectrum disorders: a meta-analysis
Researches have found that alteration of intestinal flora may be closely related to the development of autism spectrum disorder (ASD). However, whether probiotics supplementation has a protective effect on ASD...
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Article
Open AccessNitrogen addition has divergent effects on phosphorus fractions in four types of soils
Globally increasing atmospheric nitrogen (N) deposition has altered soil phosphorus (P) transformations and availability, and thereby influenced structure and function of terrestrial ecosystems. Edaphic charac...
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Article
Open AccessGenetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus
Rare genetic variants in toll-like receptor 7 (TLR7) are known to cause lupus in humans and mice. UNC93B1 is a transmembrane protein that regulates TLR7 localization into endosomes. In the present study, we id...
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Article
Association of Oxidative Stress on Cognitive Function: A Bidirectional Mendelian Randomisation Study
The purpose of this study was to investigate the relationship between oxidative stress and cognitive function, encompassing cognitive performance, intelligence, memory, reaction time, speech and vision by a bi...
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Article
Open AccessCorrection: Sodium, potassium intake, and all-cause mortality: confusion and new findings
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Article
Analysis of an Energy-Dissipating Finite Volume Scheme on Admissible Mesh for the Aggregation-Diffusion Equations
We develop the numerical analysis of an energy-dissipating finite volume scheme on admissible meshes for the non-local, nonlinear aggregation-diffusion equations. Crucially, this scheme keeps the dissipation p...
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Article
Open AccessIncorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework
The term eGene has been applied to define a gene whose expression level is affected by at least one independent expression quantitative trait locus (eQTL). It is both theoretically and empirically important to...
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Article
Open AccessSodium, potassium intake, and all-cause mortality: confusion and new findings
The World Health Organization (WHO) has established recommended daily intakes for sodium and potassium. However, there is currently some controversy regarding the association between sodium intake, potassium i...
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Chapter and Conference Paper
Study on Sliding Construction Technology of Complex Steel Structure Roof System: A Case Study of Xiamen, China
The construction of a steel structure roof is typically an exceedingly intricate system engineering, with exceedingly elevated technical and managerial demands throughout the course of construction. The insuff...
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Article
Open AccessInfluence of social deprivation on morbidity and all-cause mortality of cardiometabolic multi-morbidity: a cohort analysis of the UK Biobank cohort
The relation of social deprivation with single cardiometabolic disease (CMD) was widely investigated, whereas the association with cardiometabolic multi-morbidity (CMM), defined as experiencing more than two C...
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Article
Open AccessAssociation between remnant cholesterol, metabolic syndrome, and cardiovascular disease: post hoc analysis of a prospective national cohort study
Epidemiologic evidence suggested that remnant cholesterol (RC) is associated with the occurrence of cardiovascular disease (CVD). In recent years, RC has been connected with different types of cardiometabolic ...
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Article
Open AccessThe plasma exosomes from patients with primary Sjögren’s syndrome contain epithelial cell–derived proteins involved in ferroptosis
Primary Sjögren’s syndrome (pSS) is an autoimmune disease represented by exocrine gland epithelial cell lesions. However, the mechanism underlying these lesions remains unclear. This study analyzed the plasma ...
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Article
Open AccessPrevalence of social frailty and its associated factors in the older Chinese population: a national cross-sectional study
Social frailty has not been comprehensively studied in China. Our objective is to investigate the prevalence of social frailty among the older population in China, as well as identify relevant factors and urba...
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Article
Open AccessNeoadjuvant sintilimab in combination with concurrent chemoradiotherapy for locally advanced gastric or gastroesophageal junction adenocarcinoma: a single-arm phase 2 trial
In this multicenter, single-arm phase 2 trial (ChiCTR1900024428), patients with locally advanced gastric/gastroesophageal junction cancers receive one cycle of sintilimab (anti-PD1) and chemotherapy (S-1 and n...
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Article
How to drive strategic green innovation behavior? A qualitative comparative analysis (QCA) based on Chinese manufacturing enterprises
Green innovation is an important way for manufacturing enterprises to achieve green and high-quality development. The existing literature has ignored the heterogeneous motivations for enterprise green innovati...
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Article
Open AccessProperties of multi-GNSS uncalibrated phase delays with considering satellite systems, receiver types, and network scales
The Wide-Lane (WL) and Narrow-Lane (NL) Uncalibrated Phase Delays (UPDs) are the prerequisites in the traditional Precise Point Positioning (PPP) Ambiguity Resolution (AR). As the generation mechanism of vario...
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Article
Open AccessEvaluating significance of European-associated index SNPs in the East Asian population for 31 complex phenotypes
Genome-wide association studies (GWASs) have identified many single-nucleotide polymorphisms (SNPs) associated with complex phenotypes in the European (EUR) population; however, the extent to which EUR-associa...
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Article
Open AccessGut microbiota combined with fecal metabolomics reveals the effects of FuFang Runzaoling on the microbial and metabolic profiles in NOD mouse model of Sjögren’s syndrome
Sjögren’s syndrome (SS) is an inflammatory autoimmune disease characterized by high levels of chronic lymphocyte infiltration. Differences and dysfunction in the gut microbiota and metabolites may be closely r...