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594 Result(s)
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Article
Exploring Plasma-Induced Transparency: Coupling Plasmonic Waveguides with Resonators for Innovative Nanophotonic Applications
A novel plasmonic structure is proposed to achieve plasmon-induced transparency (PIT), which is composed of a stub resonator (SR) and a square ring resonator (SRR). The research delves into the theoretical cal...
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Article
Exploring the Spatiotemporal Changes and Driving Forces of Ecosystem Services of Zhejiang Coasts, China, Under Sustainable Development Goals
Ecosystem services (ESs) refer to the continuous provisioning of ecosystem goods and services that benefit human beings. Over recent decades, rapid urbanization has exerted significant pressure on coastal ecos...
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A cathode homogenization strategy for enabling long-cycle-life all-solid-state lithium batteries
All-solid-state lithium batteries typically employ heterogeneous composite cathodes where conductive additives are introduced to improve mixed conduction. These electrochemically inactive additives are not ful...
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Open AccessAuthor Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
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Article
Targeting net-zero emissions while advancing other sustainable development goals in China
The global net-zero transition needed to combat climate change may have profound effects on the energy–food–water–air quality nexus. Accomplishing the net-zero target while addressing other environmental chall...
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Article
Open AccessCohesin prevents cross-domain gene coactivation
The contrast between the disruption of genome topology after cohesin loss and the lack of downstream gene expression changes instigates intense debates regarding the structure–function relationship between gen...
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Open AccessAdenine base editing-mediated exon skipping restores dystrophin in humanized Duchenne mouse model
Duchenne muscular dystrophy (DMD) affecting 1 in 3500–5000 live male newborns is the frequently fatal genetic disease resulted from various mutations in DMD gene encoding dystrophin protein. About 70% of DMD-caus...
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Open AccessMining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application.
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Open AccessManagement of patient with Fusobacterim nucletum related pleural empyema: intrapleural antibiotic therapy can be considered for salvage therapy
Pleural empyema can lead to significant morbidity and mortality despite chest drainage and antibiotic treatment, necessitating novel and minimally invasive interventions. Fusobacterium nucleatum is an obligate...
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Article
Subgraph matching-based reference placement for printed circuit board designs
Reference placement is promising to handle the increasing complexity in printed circuit board (PCB) designs, which aims to find the isomorphism of the placed template in component combination to reuse the plac...
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Article
Open AccessWTCRNet: a wavelet transform and contrastive regularization network for sonar denoising by self-supervision
In the field of underwater acoustics, forward-looking sonar represents a pivotal tool for acquiring subaqueous imagery. However, this technique is susceptible to the inherent ambient noise prevalent in underwa...
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Open AccessImpact of baseline cardiovascular risk on the outcomes of intensive blood pressure intervention: a post hoc analysis of the China rural hypertension control project
The 2018/2023 ESC/ESH Guidelines underlined a gap how baseline cardiovascular disease (CVD) risk predicted blood pressure (BP) lowering benefits. Further, 2017 ACC/AHA Guideline and 2021 WHO Guideline recommen...
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Open AccessRisk factors for mortality in post-myocardial infarction patients: insights from the improve SCA bridge study
Underutilization of implantable cardioverter defibrillators (ICD) to prevent sudden cardiac death (SCD) in post-myocardial infarction (MI) patients remains an issue across several geographies. A better underst...
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Open AccessIntradermal Injection in Balding Region Versus Intramuscular Injection in Surrounding Muscles: A Split-Scalp, Randomized Trial on BoNT for Androgenetic Alopecia
Recent advancements in androgenetic alopecia (AGA) treatment have highlighted the efficacy of botulinum toxin (BoNT). However, inconsistencies in injection sites and depths warrant attention. It remains unclea...
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Article
Graphene-Enhanced Refractive Index Sensing and Narrow-band Filtering with Crossed Bicircular Resonator Cavity Waveguides
This work presents a dynamically tunable metal–insulator-metal (MIM) graphene hybrid refractive index sensor and narrow-band filter. Through the use of the finite element method (FEM), the transmission charact...
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Article
Recognition of autism spectrum disorder in children based on electroencephalogram network topology
Although our knowledge of autism spectrum disorder (ASD) has been deepened, the accurate diagnosis of ASD from normal individuals is still left behind. In this study, we proposed to apply the spatial pattern o...
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Study on the mechanism of heterogeneous tumor-associated macrophages in three subtypes of breast cancer through the integration of single-cell RNA sequencing and in vitro experiments
Tumor-associated macrophages (TAM) exert a significant influence on the progression and heterogeneity of various subtypes of breast cancer (BRCA). However, the roles of heterogeneous TAM within BRCA subtypes r...
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Open AccessIn-situ observation of silk nanofibril assembly via graphene plasmonic infrared sensor
Silk nanofibrils (SNFs), the fundamental building blocks of silk fibers, endow them with exceptional properties. However, the intricate mechanism governing SNF assembly, a process involving both protein confor...
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Article
Open AccessAplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β precursor-like protein 1 (Aplp1) interacts with Lag3...
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Article
Open AccessHHLA2 deficiency inhibits pancreatic cancer progression and THP-1 macrophage M2 polarization via EGFR/MAPK/ERK and mTOR/AKT pathway
Human endogenous retrovirus subfamily H long terminal repeat associating protein 2, (HHLA2), a member of B7 family, exhibits heightened expression in various malignant tumors. However, the exact functions of H...