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Article
Open AccessLower serum creatinine to cystatin C ratio associated with increased incidence of frailty in community-dwelling elderly men but not in elderly women
Sarcopenia has been reported to play an important role in frailty syndrome. The serum creatinine/serum cystatin C ratio (Scr/Cys C ratio) has recently been recognized as a valuable indicator for assessing sarc...
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Article
Open AccessEfficient and precise genomic deletion in rice using enhanced prime editing
Efficient and precise genomic deletion shows promise for investigating the function of proteins in plant research and enhancing agricultural traits. In this study, we tested the PRIME-Del (PDel) strategy using...
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Article
Open AccessExosome-coated oxygen nanobubble-laden hydrogel augments intracellular delivery of exosomes for enhanced wound healing
Wound healing is an obvious clinical concern that can be hindered by inadequate angiogenesis, inflammation, and chronic hypoxia. While exosomes derived from adipose tissue-derived stem cells have shown promise...
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Article
Laboratory and field evaluation of maize resistance to the two-spotted spider mite, Tetranychus urticae
Spider mites are some of the most important agricultural pests worldwide, jeopardizing maize production across many continents. However, mechanisms of resistance to spider mite in maize remain unclear. Here, w...
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Article
Experimental and Theoretical Study on Catenary Mechanism of Steel Frame Beam Subject to Fire
Two fire tests were carried out on planar steel sub-frames to study the catenary mechanism of steel frame beams exposed to fire. The temperature distribution of steel frame structure and catenary mechanism of ...
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Article
Energy efficiency characteristic analysis of tri-coil PT symmetric MC-WPT systems
The parity-time (PT) symmetric magnetic coupling wireless power transfer (MC-WPT) system has received a great deal of attention since it was proposed. Its transmission efficiency has been greatly improved when...
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Article
Trash to treasure: lactate and protein lactylation in maize root impacts response to drought
Lactate, protein lactylation (Kla), and specifically histone lactylation have recently been shown to regulate antipathogenic immune responses in mammals. Herein, after we confirmed the presence and accumulatio...
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Article
Lower abundance of Bacteroides and metabolic dysfunction are highly associated with the post-weaning diarrhea in piglets
Growing evidences show a direct link between diarrhea and disorders of gut microbiota in pigs. However, whether there are microbial markers associated with post-weaning diarrhea remains unknown. In the current...
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Article
Open AccessiTRAQ-based quantitative proteomic analysis provides insight into the drought-stress response in maize seedlings
Drought is a major abiotic stress that harms plant cell physiology and limits the growth and productivity of crops. Maize (Zea mays L.), one of the most drought-susceptible crops, is a major food source for human...
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Article
Nimodipine Attenuates Early Brain Injury by Protecting the Glymphatic System After Subarachnoid Hemorrhage in Mice
The glymphatic system (GS) plays an important role in subarachnoid hemorrhage (SAH). Nimodipine treatment provides SAH patients with short-term neurological benefits. However, no trials have been conducted to ...
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Chapter and Conference Paper
Direct Current Voltage Prediction Control Method Based on the Rate of Load Current
With the arriving of 5G age, the DC power supply system is increasing to apply to the data center, and performance requirements of the rectifier module which is the main components of the data center is increa...
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Article
A design optimized prime editor with expanded scope and capability in plants
The ability to manipulate the genome in a programmable manner has illuminated biology and shown promise in plant breeding. Prime editing, a versatile gene-editing approach that directly writes new genetic info...
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Article
Indication of the prognosis of pulmonary hypertension by using CMR function parameters
This study aimed to compare the cardiac function among different sub-types of pulmonary hypertension (PH) and to explore the independent predictors of major adverse cardiovascular events (MACE).
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Article
Open AccessIs oral microbiome of children able to maintain resistance and functional stability in response to short-term interference of ingesta?
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Article
Electrospinning Janus Nanofibrous Membrane for Unidirectional Liquid Penetration and Its Applications
Janus membrane with opposite wettability on its two sides has witnessed an explosion of interest in the field of liquid spontaneous and directional transport for their promising prospect. The advances in fabric.....
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Article
Correction: A novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination
A Correction to this paper has been published: https://doi.org/10.1038/s41388-021-01717-5
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Article
Probabilistic collapse analysis of steel frame structures exposed to fire scenarios
In this paper, we propose a probabilistic method for analysing the collapse time of steel frame structures in a fire. The method considers the uncertainty of influencing factors. Tornado diagrams are used for ...
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Article
Open AccessA novel UBE2T inhibitor suppresses Wnt/β-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination
Dysregulation of the Wnt/β-catenin signaling pathway is critically involved in gastric cancer (GC) progression. However, current Wnt pathway inhibitors being studied in preclinical or clinical settings for oth...
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Article
Design and synthesis of novel spirooxindole–indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors
In the current study, we used an integrated approach combining bioinformatics, rational drug design, one-pot synthesis, and biological experiments in vitro for the potential discovery of novel tryptophanyl-tRN...
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Article
CO2 adsorption performance of CuBTC/graphene aerogel composites
Metal-organic frameworks (MOFs) have been recognized as promising adsorbents for carbon capture due to their ultrahigh surface areas and tunable properties. However, a majority of MOFs have strict requirements...