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Article
Four mutations identified in Chinese families with autosomal dominant congenital cataracts by next-generation sequencing
Congenital cataracts, which can arise due to a combination of factors like environmental influences and genetic predisposition, significantly impact children’s visual health globally. The occurrence rate of co...
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Article
Structure-Guided Evolution Modulate Alcohol Oxidase to Improve Ethanol Oxidation Performance
A high ethanol usage of alcohol oxidase (AOX) was required in industry. In this study, a “expand substrate pocket” strategy achieved a high activity AOX from Hansenula polymorpha (H. polymorpha) by Phe to Val res...
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Article
Open AccessTissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox
Retinal pigment epithelium (RPE) cell therapy is a promising way to treat many retinal diseases. However, obtaining transplantable RPE cells is time-consuming and less effective. This study aimed to develop no...
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Article
Open AccessKoningipyridines A and B, two nitrogen-containing polyketides from the fungus Trichoderma koningiopsis SC-5
Two novel koninginin derivatives, koningipyridines A and B (1 and 2), along with four known compounds (3˗6) were isolated from the EtOAc extract of the endophytic fungus Trichoderma koningiopsis SC-5. Among them,...
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Article
A single-mode chalcogenide photonic crystal fiber for bending resistance with large mode area and wide bandwidth
In this paper, a large mode area photonic crystal fiber (PCF) based on chalcogenide glass \(As_{2}S_{3}\) ...
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Article
Open AccessApplication of Induced Pluripotent Stem Cells in Malignant Solid Tumors
In the past decade, induced pluripotent stem cells (iPSCs) technology has significantly progressed in studying malignant solid tumors. This technically feasible reprogramming techniques can reawaken sequestere...
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Article
Design of hexagonal photonic crystal fiber with Ge10As22Se68 chalcogenide core and As2S3 cladding for mid-infrared supercontinuum generation
In this paper, we propose a hexagonal photonic crystal fiber (PCF) suitable for broadened mid-infrared supercontinuum generation. The designed PCF has five air-hole rings with three different air holes, arrang...
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Article
Open AccessSuppressing electron-phonon coupling in organic photovoltaics for high-efficiency power conversion
The nonradiative energy loss (∆Enr) is a critical factor to limit the efficiency of organic solar cells. Generally, strong electron-phonon coupling induced by molecular motion generates fast nonradiative decay an...
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Article
Weathering properties of wood treated with 3-isocyanatopropyltriethoxysilane-TiO2
Plantation poplar is one of the most commonly used fast-growing woods in China. However, it is susceptible to weathering due to climatic conditions such as sunlight irradiation, rain, temperature changes, and ...
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Article
Modeling and Simulation of Sintering Process Across Scales
Sintering, as a thermal process at elevated temperature below the melting point, is widely used to bond contacting particles into engineering products such as ceramics, metals, polymers, and cemented carbides....
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Article
Multilayer Structured CaBi4Ti4O15 Thin Film Capacitor with Excellent Energy Storage Performance
Ferroelectric Aurivillius compounds have the unique electric resistance and fatigue-free features due to the natural superlattice structure, which is benefit for exploring high energy storage performance. Howe...
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Article
Open AccessAlterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer
Current diagnosis tools for prostate cancer (PCa) such as serum PSA detection and prostate biopsy cannot distinguish dormant tumors from invasive malignancies, either be used as prognosis marker for castration...
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Article
In vitro adventitious shoot regeneration system for Agrobacterium-mediated genetic transformation of Fraxinus mandshurica Rupr.
Using hypocotyls as explants, an in vitro adventitious shoot regeneration system of Manchurian ash was established, and it has been successfully applied in Agrobacterium-mediated genetic transformation.
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Article
Open AccessLaBr2 bilayer multiferroic moiré superlattice with robust magnetoelectric coupling and magnetic bimerons
Two-dimensional (2D) van der Waals (vdW) materials provide the versatile playground to stack two or more vdW layers for creation of superior materials with desired properties. Here we theoretically adopt a twi...
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Article
High-κ perovskite membranes as insulators for two-dimensional transistors
The scaling of silicon metal–oxide–semiconductor field-effect transistors has followed Moore’s law for decades, but the physical thinning of silicon at sub-ten-nanometre technology nodes introduces issues such...
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Article
A New Stilbenoid from Caryopteris incana
A new stilbenoid, methyl 2,4-dihydroxy-6-(4-hydroxyphenethyl)-3-methylbenzoate (1), along with 11 known compounds, cirsimaritin (2), cirsiliol (3), quercetin (4), apigenin (5), acacetin (6), genkwanin (7), luteol...
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Chapter and Conference Paper
Research on Photovoltaic Grid Connected Inverter Without Isolation Transformer
Traditional photovoltaic grid connected inverter usually has power frequency transformer or high frequency transformer, which brings many inconvenience. Due to the existence of equivalent parasitic capacitance...
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Chapter and Conference Paper
Med-DANet: Dynamic Architecture Network for Efficient Medical Volumetric Segmentation
For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice ma...
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Article
Open AccessA chromosome-level genome assembly of Cairina moschata and comparative genomic analyses
The Muscovy duck (Cairina moschata) is an economically important duck species, with favourable growth and carcass composition parameters in comparison to other ducks. However, limited genomic resources for Muscov...
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Article
Open AccessBerlin Green Framework-Based Gas Sensor for Room-Temperature and High-Selectivity Detection of Ammonia
Berlin green (BG) framework is highly promising for ammonia detection demonstrated by both theoretical and experimental investigations.