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Open Access“Documentation is now so ingrained in me”: how students interpret and value documentation in creative learning domains
Within creative domains in studio- and project-based education, documentation is often central to demonstrating outcomes, process, and progress. Despite much prior work into the instructional practices, techno...
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Article
Open AccessAxillary vein as an alternative venous access site for VV-ECMO cannulation: a case report
Ultrasound-guided percutaneous axillary vein cannulation can reduce cannulation failure and mechanical complications, is as safe and effective as internal jugular vein cannulation, and is superior to subclavia...
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Article
Significance of Oxidative Stress in the Diagnosis and Subtype Classification of Intervertebral Disc Degeneration
Intervertebral disc degeneration (IVDD) is a common illness of aging, and its pathophysiological process is mainly manifested by cell aging and apoptosis, an imbalance in the production and catabolism of extra...
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Article
An optimized data interaction structure for SERCOS-based open CNC system
With the wide acceptance of open CNC systems and the rapid development of network technology, end-users can easily integrate control strategies or intelligent algorithm modules into open CNC systems. The openn...
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Article
Incorporating a new perspective of Z-number into ELECTRE II with group consensus involving reliance degree and prospect theory
Z-number expresses the membership degrees of an element to a set by several possibilities and their reliability. Therefore, it has a great advantage in dealing with fuzziness and uncertainty especially for mul...
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Article
Flood risk assessment of metro stations based on the SMAA-2-FFS-H method: a case study of the “7 \(\cdot\) 20” rainstorm in Zhengzhou, China
Motivated by the realistic demand of reducing the flood risk of urban metro stations, this paper proposes an innovative research framework for flood risk assessment and classification. In this framework, a spe...
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Article
Open AccessProphylactic noninvasive respiratory support in the immediate postoperative period after cardiac surgery - a systematic review and network meta-analysis
Noninvasive respiratory support has been increasingly applied in the immediate postoperative period to prevent postoperative pulmonary complications (PPCs). However, the optimal approach remains uncertain. We ...
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Article
Open AccessVariation in central venous oxygen saturation to evaluate fluid responsiveness: a systematic review and meta-analysis
Since oxygen content and oxygen consumption typically remain unchanged within a short period, variation in central venous oxygen saturation (ΔScvO2) during fluid challenge can theoretically track the changes in c...
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Article
Integrated BWM-Entropy weighting and MULTIMOORA method with probabilistic linguistic information for the evaluation of Waste Recycling Apps
Based on the encouragement and increasingly recycling demands of the Chinese governments, online recycling platforms based on B2C, such as loving recycling app, waste recycling alliance app, have emerged as th...
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Article
Open AccessSuccessful management of hemodynamic instability secondary to saddle pulmonary embolism-induced cardiac arrest using VA-ECMO in advanced malignancy with brain metastases
Saddle pulmonary embolism (SPE) represents a rare type of venous thromboembolism that frequently causes circulation collapse and sudden death. While venoarterial extracorporeal membrane oxygenation (VA-ECMO) h...
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Article
A Novel Group TODIM Method Based on Multi-Granularity Proportional Hesitant Fuzzy Linguistic Term Sets for Water Resources Risk Evaluation
The risk of water resources has become a serious crisis threatening the human survival and social development. Based on the establishment of a comprehensive risk evaluation system from perspective of water qua...
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Article
Open AccessSpinal cord infarction secondary to pulmonary embolism-induced cardiac arrest: a case report
Pulmonary embolism is a common cause of cardiac arrest. Pulmonary embolism-induced cardiac arrest typically suffers from ischemic injuries to various organs, including the central nervous system. However, spin...
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Article
Open AccessThe ROX index as a predictor of high-flow nasal cannula outcome in pneumonia patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis
The respiratory rate-oxygenation (ROX) index has been increasingly applied to predict the outcome of high-flow nasal cannula (HFNC) in pneumonia patients with acute hypoxemic respiratory failure (AHRF). Howeve...
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Article
Open AccessOptimizing left ventricular-arterial coupling during the initial resuscitation in septic shock – a pilot prospective randomized study
Left ventricular-arterial coupling (VAC), defined as the ratio of effective arterial elastance (Ea) to left ventricular end-systolic elastance (Ees), has been extensively described as a key determinant of card...
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Article
Open AccessPCSK9 inhibitor recaticimab for hypercholesterolemia on stable statin dose: a randomized, double-blind, placebo-controlled phase 1b/2 study
Recaticimab (SHR-1209, a humanized monoclonal antibody against PCSK9) showed robust LDL-C reduction in healthy volunteers. This study aimed to further assess the efficacy and safety of recaticimab in patients ...
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Article
Open AccessPrevotellaceae produces butyrate to alleviate PD-1/PD-L1 inhibitor-related cardiotoxicity via PPARα-CYP4X1 axis in colonic macrophages
Immune checkpoint inhibitor-related cardiotoxicity is one of the most lethal adverse effects, and thus, the identification of underlying mechanisms for developing strategies to overcome it has clinical importa...
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Article
Open AccessPredictive performance of dynamic arterial elastance for arterial pressure response to fluid expansion in mechanically ventilated hypotensive adults: a systematic review and meta-analysis of observational studies
Dynamic arterial elastance (Eadyn) has been extensively considered as a functional parameter of arterial load. However, conflicting evidence has been obtained on the ability of Eadyn to predict mean arterial pres...
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Article
Open AccessLeft ventricular-arterial coupling as a predictor of stroke volume response to norepinephrine in septic shock – a prospective cohort study
Left ventricular-arterial coupling (VAC), defined as the ratio of arterial elastance (Ea) to left ventricular end-systolic elastance (Ees), is a key determinant of cardiovascular performance. This study aims t...
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Article
Open AccessCOVID-19 patients with hypertension are at potential risk of worsened organ injury
In less than 6 months, COVID-19 spread rapidly around the world and became a global health concern. Hypertension is the most common chronic disease in COVID-19 patients, but its impact on these patients has no...
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Article
Production of gene-edited pigs harboring orthologous human mutations via double cutting by CRISPR/Cas9 with long single-stranded DNAs as homology-directed repair templates by zygote injection
Precise gene editing of model organisms is required for accurately modeling human diseases and deciphering gene functions. In this study, we used a pair of guide RNAs (sgRNAs), which in vitro transcribed along...