219 Result(s)
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Open AccessThe Brain Salience Network at the Intersection of Pain and Substance use Disorders: Insights from Functional Neuroimaging Research
The brain’s salience network (SN), primarily comprising the anterior insula and anterior cingulate cortex, plays a key role in detecting salient stimuli and processing physical and socioemotional pain (e.g., s...
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Open AccessQuantitative CT analysis of idiopathic pulmonary fibrosis and correlation with lung function study
Idiopathic Pulmonary Fibrosis (IPF) is a progressive fibrotic lung disease. However, the field of quantitative CT scan analysis in conjunction with pulmonary function test for IPF patients remains relatively u...
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Open AccessMedial prefrontal neuroplasticity during extended-release naltrexone treatment of opioid use disorder – a longitudinal structural magnetic resonance imaging study
Opioid use disorder (OUD) has been linked to macroscopic structural alterations in the brain. The monthly injectable, extended-release formulation of μ-opioid antagonist naltrexone (XR-NTX) is highly effective...
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Open AccessRenalase rs2296545 variant improve hypertension susceptibility by modifying binding affinity to catecholamines in obstructive sleep apnea
Obstructive sleep apnea (OSA), a condition often linked with hypertension, has an undefined relationship with renalase, a protein known for regulating blood pressure. This study aimed to investigate the relati...
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Exploring Research Trend and Hotspots on Oxidative Stress in Ischemic Stroke (2001–2022): Insights from Bibliometric
Oxidative stress is widely involved in the pathological process of ischemic stroke and ischemia-reperfusion. Several research have demonstrated that eliminating or reducing oxidative stress can alleviate the p...
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N2 component implied a subjective conflict detection thinking strategy: an event-related potential study of the covariation detection task
Previous research on decision-making tasks suggests that material differences between conflict and non-conflict questions induce differences in the N2 component. However, varying thinking strategies of individ...
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Theoretical study of potential energetic material CL-20/DNAN eutectic explosive based on molecular dynamics method
The exploration of CL-20 eutectic has been a subject of fervent interest within the realm of high-energy material modification. Through the utilization of density functional and molecular dynamics methods, an ...
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Guest-adaptive chiral coassembly of a conformationally locked host into supramolecular boxes and ladders through arene-perfluoroarene force
Unveiling the role of weak non-covalent forces in chiral self-assembly is pivotal in the design and fabrication of functional chiroptical materials. The nature of arene-perfluoroarene (AP) force is the electro...
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Simple Fabrication of Nb2O5/PANI Nanocomposite on Self-Supporting Carbon Cloth for High Performance Lithium-Sulfur Batteries
Lithium-sulfur batteries have attracted significant attention due to their high theoretical capacity density (1675 mA h g− 1) and low production cost. However, under practical conditions, the low conductivity of ...
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Triglyceride-glucose index predicts major adverse cardiovascular events in patients with chronic kidney disease
Triglyceride-glucose (TyG) index has been regarded as a reliable surrogate marker of insulin resistance for predicting cardiovascular outcomes. The current study aimed to explore the associations between TyG i...
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Protein-sparing effects of lipids in the diet of golden pompano (Trachinotus ovatus): evaluation of growth, feed utilization, and lipid metabolism
To investigate the influences of dietary protein and lipid levels on the growth, feed utilization, morphometric parameters, body composition, serum biochemical parameters, and lipid metabolism of golden pompano (
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Expanding the genetic and phenotypic relevance of CLCN4 variants in neurodevelopmental condition: 13 new patients
CLCN4 variations have recently been identified as a genetic cause of X-linked neurodevelopmental disorders. This study aims to broaden the phenotypic spectrum of CLCN4-related condition and correlate it with func...
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Open AccessJNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans
The interleukin (IL)-23 pathway is a pathogenic driver in psoriasis, psoriatic arthritis, and inflammatory bowel disease. Currently, no oral therapeutics selectively target this pathway. JNJ-77242113 is a pept...
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Open AccessTargeted nanoparticles triggered by plaque microenvironment for atherosclerosis treatment through cascade effects of reactive oxygen species scavenging and anti-inflammation
Inflammatory factors and reactive oxygen species (ROS) are risk factors for atherosclerosis. Many existing therapies use ROS-sensitive delivery systems to alleviate atherosclerosis, which achieved certain effi...
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Correction to: Triglyceride‑glucose index predicts major adverse cardiovascular events in patients with chronic kidney disease
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Article
Sharp Asymptotics for Arm Probabilities in Critical Planar Percolation
In this work, we consider critical planar site percolation on the triangular lattice and derive sharp estimates on the asymptotics of the probability of half-plane j-arm events for
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Open AccessQuantitative assessment of preoperative brain development in pediatric congenital heart disease patients by synthetic MRI
This study investigated the quantitative assessment and application of Synthetic MRI (SyMRI) for preoperative brain development in children with congenital heart disease (CHD).
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Open AccessRelationships between apolipoprotein E and insulin resistance in patients with obstructive sleep apnoea: a large-scale cross-sectional study
Obstructive sleep apnoea (OSA) is commonly associated with insulin resistance (IR) and dyslipidaemia. Apolipoprotein E (APOE) plays important roles in lipid metabolism. The study aimed to disentangle the multi...
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Monitoring and analysis of side-slope deformation along Changgan high-speed railway based on time-series InSAR and BDS techniques
The stability of side slope is very important to the construction and operation of high-speed railway. In this study, we proposed to jointly apply Interferometric synthetic aperture radar (InSAR) and BeiDou Na...
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Norepinephrine–Astrocyte Signaling Regulates Cortical State Homeostasis