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157 Result(s)
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Article
Pannonibacter tanglangensis sp. nov., a New Species Isolated from Pond Sediment
Two bacterial strains (XCT-34T and XCT-53) isolated from sediment samples of an artificial freshwater reservoir were analyzed using a polyphasic approach. The two isolates are aerobic, Gram-stain-negative, oxidas...
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Article
Open AccessTWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in triple-negative breast cancer
Triple Negative Breast Cancer (TNBC) is the most aggressive breast cancer subtype suffering from limited targeted treatment options. Following recent reports correlating Fibroblast growth factor-inducible 14 (...
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Article
Open AccessCosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction
Missions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as t...
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Article
Data-driven model identification and control of the quasi-zero-stiffness system
Nonlinear vibraion isolation technique is widely employed for vibration suppression. An identification-control integrated method based on data-driven approaches is proposed for solving the optimal control law ...
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Article
Open AccessActivating the healing process: three-dimensional culture of stem cells in Matrigel for tissue repair
To establish a strategy for stem cell-related tissue regeneration therapy, human gingival mesenchymal stem cells (hGMSCs) were loaded with three-dimensional (3D) bioengineered Matrigel matrix scaffolds in high...
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Article
Open AccessNeurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8+ T cells in cerebral malaria
Cerebral malaria (CM) is the most lethal complication of malaria, and survivors usually endure neurological sequelae. Notably, the cytotoxic effect of infiltrating Plasmodium-activated CD8+ T cells on cerebral mi...
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Article
Open AccessThiamine-modified metabolic reprogramming of human pluripotent stem cell-derived cardiomyocyte under space microgravity
During spaceflight, the cardiovascular system undergoes remarkable adaptation to microgravity and faces the risk of cardiac remodeling. Therefore, the effects and mechanisms of microgravity on cardiac morpholo...
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Article
Vibration Suppression of Optical Payload Based on Parallel Manipulator
Currently, the observational resolution of Earth observation satellites and space telescopes is progressively advancing. Nevertheless, the detrimental effects of vibrations induced by solar panel oscillation, ...
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Article
Open AccessBoosting Hydrogen Storage Performance of MgH2 by Oxygen Vacancy-Rich H-V2O5 Nanosheet as an Excited H-Pump
Graphene-like 2D V2O5 nanosheets rich in oxygen vacancies are designed as multi-functional catalysts to fabricate MgH2-H-V2O5 composites.
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Article
Open AccessAberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma
In multiple myeloma, abnormal plasma cells establish oncogenic niches within the bone marrow by engaging the NF-κB pathway to nurture their survival while they accumulate pro-proliferative mutations. Under the...
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Article
Open AccessFixed-time angle of attack constrained control for aircraft considering dynamic icing process
Aircraft icing deteriorates aerodynamic performance and reduces stall angle of attack, the fast convergence rate of tracking error is required to stabilize the aircraft when aircraft icing occurs. The state-of...
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Article
Open AccessSingle dose recombinant VSV based vaccine elicits robust and durable neutralizing antibody against Hantaan virus
Hantaan virus (HTNV) is a pathogenic orthohantavirus prevalent in East Asia that is known to cause hemorrhagic fever with severe renal syndrome (HFRS), which has a high fatality rate. However, a Food and Drug ...
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Article
Contrasting Iron Metabolism in Undifferentiated Versus Differentiated MO3.13 Oligodendrocytes via IL-1β-Induced Iron Regulatory Protein 1
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder characterized by the loss of dopaminergic neurons and the accumulation of iron in the substantia nigra. While iron accumulation and inflammati...
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Article
Open AccessQuantitative ultrasound image assessment of the optic nerve subarachnoid space during 90-day head-down tilt bed rest
The elevation in the optic nerve sheath (ONS) pressure (ONSP) due to microgravity-induced headward fluid shift is the primary hypothesized contributor to SANS. This longitudinal study aims to quantify the axia...
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Article
Open AccessMaxillofacial growth changes after maxillary protraction therapy in children with class III malocclusion: a dual control group retrospective study
To investigate the balance between post-treatment effect and continued nature growth after maxillary protraction treatment in patients with skeletal class III malocclusion.
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Chapter and Conference Paper
Semi-Analytic Solutions for the Bending-Bending-Torsion Coupled Forced Vibrations of a Rotating Wind Turbine Blade by Means of Green’s Functions
In recent years, wind power has received continuous attention as a renewable energy source in the context of carbon neutrality. Blades in wind turbines with elongated structures are susceptible to damage due t...
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Article
Effects of Thirty Days Isolation on Attention Networks: A Behavioral and Event-related Potential Study
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Article
Open AccessDesign of A Novel Wheel-Legged Robot with Rim Shape Changeable Wheels
The wheel-legged hybrid structure has been utilized by ground mobile platforms in recent years to achieve good mobility on both flat surfaces and rough terrain. However, most of the wheel-legged robots only ha...
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Article
Erratum to: Phase-field simulation of lack-of-fusion defect and grain growth during laser powder bed fusion of Inconel 718
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Article
Dynamic Nonlinear Analysis of Functionally Graded Flow Pipelines with Defects Based on Different Foundation Layouts
The dynamic characteristics of fluid-conveying pipelines with an initial deflection on nonlinear elastic foundation with local distribution and discrete point arrangement are studied.