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Article
Open AccessCircular RNA hsa_circ_0050386 suppresses non-small cell lung cancer progression via regulating the SRSF3/FN1 axis
Lung cancer is the most prevalent cancer worldwide, with non-small cell lung cancer (NSCLC) accounting for 85% of all cases. Circular RNAs(circRNA) play crucial roles in regulating the progression of lung canc...
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Article
A novel LINC00478 serves as a tumor suppressor in endometrial carcinoma progression
Long noncoding RNAs (lncRNAs) are involved in the pathogenesis and progression of various cancers, but their roles in endometrial cancer (EC) are largely unknown.
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Article
Open AccessAn EMT-related genes signature as a prognostic biomarker for patients with endometrial cancer
The epithelial-mesenchymal transition (EMT) plays an indispensable role in the development and progression of Endometrial cancer (EC). Nevertheless, little evidence is reported to uncover the functionality and...
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Article
miR-181c, a potential mediator for acute kidney injury in a burn rat model with following sepsis
The miRNA profile is changed after burn or sepsis and is involved in regulating inflammatory reactions. However, the function and molecular mechanism of miRNAs in regulating burn sepsis-induced acute kidney in...
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Article
Open AccessPathogen Distribution and Antimicrobial Resistance of Early Onset Sepsis in Very Premature Infants: A Real-World Study
Early onset sepsis (EOS) remains a potentially fatal newborn condition, especially in very preterm infants. Data on the pathogen distribution and antibiotic susceptibility patterns of EOS among very preterm in...
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Article
Open AccessAssociation Between Antibiotic Overexposure and Adverse Outcomes in Very-Low-Birth-Weight Infants Without Culture-Proven Sepsis or Necrotizing Enterocolitis: A Multicenter Prospective Study
To explore the associations between higher antibiotic use rates (AURs) and adverse outcomes in very-low-birth-weight (VLBW) infants without culture-proven sepsis or necrotizing enterocolitis (NEC) in a multice...
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Article
Open AccessNovel genotypes of Coxiella burnetii circulating in rats in Yunnan Province, China
Coxiella burnetii (Cb) is the causative agent of the zoonotic disease Q fever which is distributed worldwide. Molecular typing of Cb strains is essential to find out the infectious source and prevent Q fever outb...
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Article
Open AccessPathogens distribution and antimicrobial resistance in bloodstream infections in twenty-five neonatal intensive care units in China, 2017–2019
Overcrowding, abuse of antibiotics and increasing antimicrobial resistance negatively affect neonatal survival rates in developing countries. We aimed to define pathogens and their antimicrobial resistance (AM...
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Article
Open AccessIdentification of tick-borne pathogens by metagenomic next-generation sequencing in Dermacentor nuttalli and Ixodes persulcatus in Inner Mongolia, China
Hard ticks act as arthropod vectors in the transmission of human and animal pathogens and are widely distributed in northern China. The aim of this study is to screen the important tick-borne pathogens (TBPs) ...
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Chapter
Ensuring Food and Drug Safety
“Food safety is a big issue, and drug safety is a matter of life.” The security of food and drug (including five types of products: food, medicine, health food, medical equipment, cosmetics and so on, hereinaf...
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Chapter
The Overall Deepening of Medical and Health System Reform
Deepening the reform of medical and health system, greatly focused on by the Party Central Committee and the State Council, is an important part of comprehensively deepening reform and a major livelihood proje...
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Chapter
Intensifying International Exchanges and Cooperation
The “Outline for Strengthening International Exchanges and Cooperation” has made in-depth expositions on strengthening international exchanges and cooperation and actively participating in global health govern...
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Chapter
Promoting Science and Technology Innovation in Healthcare
Our society is in the process of modernization. With economic development, social progress and rapid improvement of people’s living standards, industrialization, urbanization, informatization and international...
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Chapter
“Healthy China 2030”: Promoting Health and Longevity of the Whole Nation
Health and longevity are not only the core objective of human development, but also the common wishes of people of all ethnic groups in our country. Healthy China is the China where the people can enjoy health...
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Chapter
Urbanization and Building a Healthy China
Firstly, the rapid development of urbanization has led to an increasing population of agricultural transfer. In 1978–2015, the urbanization rate in China increased by around 1.03 percentage points annually on ...
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Chapter
Healthy Living for All
Healthy living refers to the habitual behaviors beneficial to one’s health, which should include the following aspects: well-balanced diets, moderate exercises, tobacco and alcohol control and psychological ba...
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Chapter
Promoting Universal Access to Public Health Services
Major diseases refer to the illnesses that severely endanger public health and life safety of the people, severely affect the national economy and the development of society, and severely impair national secur...
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Chapter
Delivery of High-Quality and Efficient Medical Care
With rapidly increased number of medical institutions and ward beds as well as expanded scale of medical institutions, great achievements have been made in the medical and health service systems during the 12t...
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Chapter
Letting Traditional Chinese Medicine Play Its Unique Role
Traditional Chinese medicine is a treasure of Chinese ancient science and also a valuable fortune in the construction of a healthy China. TCM-based unique outlook on life, health, disease and prevention has be...
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Chapter
Improving the Drug Supply Security System
Making improving the drug supply security system as an important task, the Outline of the Healthy China 2030 Plan requires to deepen the reform of the drug and device circulation system and to improve the nationa...