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689 Result(s)
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Article
The Relationship Between Metal Exposure and HPV Infection: Evidence from Explainable Machine Learning Methods
HPV is a ubiquitous pathogen implicated in cervical and other cancers. Although vaccines are available, they do not encompass all subtypes. Meanwhile, metal exposure may elevate the risk of HPV infection and ...
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Open AccessNaringenin ameliorates amyloid-β pathology and neuroinflammation in Alzheimer’s disease
Alzheimer’s disease (AD) is the most common cause of dementia characterized by amyloid-β (Aβ) deposition, tau hyperphosphorylation, and neuroinflammation. Naringenin (NRG), a natural flavonoid widely present i...
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Article
Open AccessKIAA1429 increases FOXM1 expression through YTHDF1–mediated m6A modification to promote aerobic glycolysis and tumorigenesis in multiple myeloma
Multiple myeloma (MM) is a deadly plasma cell malignancy with elusive pathogenesis. N6-methyladenosine (m6A) is critically engaged in hematological malignancies. The function of KIAA1429, the largest component...
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Response of phytoplankton functional group to spring drought in a large subtropical reservoir
Global warming has caused an increase in the frequency and duration of droughts worldwide. Droughts could trigger large changes in physico-chemical conditions and phytoplankton community in waterbodies, result...
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Open AccessTargeted materials discovery using Bayesian algorithm execution
Rapid discovery and synthesis of future materials requires intelligent data acquisition strategies to navigate large design spaces. A popular strategy is Bayesian optimization, which aims to find candidates th...
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Open AccessCorrection: Mesenchymal stem cell-derived microvesicles improve intestinal barrier function by restoring mitochondrial dynamic balance in sepsis rats
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Article
Spatial-temporal distribution and fluxes of microplastics in Jiulong River basin
Microplastics (MPs) pollution has emerged as a critical global environmental issue, for which rivers serve as key conduits for the transport of MPs from land to ocean. There remained a lack of clarity regardin...
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Study on the microscopic pore permeability behavior of granite under multiple cycles of cold-hot alternating damage effects
In the process of harnessing geothermal energy, the enduring effects of thermal cycling on granite within the geothermal reservoir led to alterations in rock permeability. This, in turn, directly impacts the e...
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Article
Role of ZNF334 in cervical cancer: implications for EMT reversal and tumor suppression
Zinc-finger proteins are involved in many biological processes. However, the role of Zinc-finger protein 334 (ZNF334) in cervical cancer remains unidentified. This study showed that promoter methylation of ZNF...
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Article
Open AccessAssessment of OCT-Based Macular Curvature and Its Relationship with Macular Microvasculature in Children with Anisomyopia
To evaluate the intraocular differences in optical coherence tomography (OCT)-based macular curvature index (MCI) among children with anisomyopia and to investigate the relationship between MCI and the macular...
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Article
Influence of Litter and Nitrogen Addition on Carbon and Nitrogen Levels in Soil Aggregates under a Subtropical Forest
The purpose of this study was to evaluate the responses of carbon (C) and nitrogen (N) in dry and wet sieved aggregates or particles to the litter treatment and N addition, in a forest ecosystem, assuming that...
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Article
Open AccessDevelopment of graphitic carbon nitride quantum dots-based oxygen self-sufficient platforms for enhanced corneal crosslinking
Keratoconus, a disorder characterized by corneal thinning and weakening, results in vision loss. Corneal crosslinking (CXL) can halt the progression of keratoconus. The development of accelerated corneal cross...
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Article
Oncoprotein LAMTOR5-mediated CHOP silence via DNA hypermethylation and miR-182/miR-769 in promotion of liver cancer growth
C/EBP homologous protein (CHOP) triggers the death of multiple cancers via endoplasmic reticulum (ER) stress. However, the function and regulatory mechanism of CHOP in liver cancer remain elusive. We have reporte...
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Thermal transports in the MXenes family: Opportunities and challenges
The carbides and nitrides of transition metals known as “MXenes” refer to a fast-growing family of two-dimensional materials discovered in 2011. Thanks to their unique nanolayer structure, superior electrical,...
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Article
Open AccessWhich factors are associated with adverse prognosis in multiple myeloma patients after surgery? - preliminary establishment and validation of the nomogram
To investigate the prognosis of patients with Multiple Myeloma (MM) after surgery, analyze the risk factors leading to adverse postoperative outcomes, and establish a nomogram.
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Article
Cyber-Physical Wireless Networks for Smart Health Monitoring for Elderly Persons
The rapid advancement in Cyber-Physical Systems (CPS) and wireless networking technologies has ushered in a new era for healthcare, particularly in the domain of smart health monitoring for elderly populations...
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Article
Optical fiber magnetic field sensor based on Fabry–Perot interferometer and magnetostrictive effect
An air gap Fabry–Perot fiber interferometric magnetic field sensor based on magnetostrictive effect is proposed. The sensor is composed of single mode fiber (SMF), silica capillary and magnetostrictive materia...
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Article
Open AccessQualitative and quantitative MRI analysis of alveolar soft part sarcoma: correlation with histological grade and Ki-67 expression
To investigate the correlation between MRI findings and histological features for preoperative prediction of histological grading and Ki-67 expression level in alveolar soft part sarcoma (ASPS).
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Article
Anomaly Detection in Metaverse Healthcare and Fitness: Bigdata Analytics Using 6G-Enabled Internets of Things
The healthcare and fitness industries are experiencing an unparalleled surge of big data from virtual environments, wearable technology, and networked systems because of how quickly the metaverse has expanded....
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Open AccessEnhanced abscopal anti-tumor response via a triple combination of thermal ablation, IL-21, and PD-1 inhibition therapy
Despite the success of immune checkpoint inhibitors (ICIs) in treating solid tumors, lots of patients remain unresponsive to this therapy. Microwave ablation (MWA) stimulates systemic adaptive immunity against...