142 Result(s)
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Article
Aesthetic Temporal Augmentation with the Pedicled Temporoparietal Fascia Flap
The contour of the temple area can significantly influence the overall facial shape and proportions. To date, various methods and techniques have been used to augment the deficient temporal fossa; however, eac...
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Article
Open AccessAcetylation-dependent regulation of core spliceosome modulates hepatocellular carcinoma cassette exons and sensitivity to PARP inhibitors
Despite the importance of spliceosome core components in cellular processes, their roles in cancer development, including hepatocellular carcinoma (HCC), remain poorly understood. In this study, we uncover a c...
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Article
Novel Iminocoumarin-substituted Tetraphenylethylene-based Near-infrared Fluorescent Probe for Ratiometric Detection of F− and H2S
An iminocoumarin and tetraphenylethylene compound that exhibits aggregation-induced emission (AIE) and a significant Stokes shift (Δλ = 135 nm) in THF was created via the Knoevenagel condensation method. TPICBT c...
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Article
Open AccessWogonin upregulates SOCS3 to alleviate the injury in Diabetic Nephropathy by inhibiting TLR4-mediated JAK/STAT/AIM2 signaling pathway
Diabetic nephropathy (DN) is a life-threatening renal disease and needs urgent therapies. Wogonin is renoprotective in DN. This study aimed to explore the mechanism of how wogonin regulated high glucose (HG)-i...
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Rapid and specific detection of Chinook salmon bafinivirus (CSBV) in flatfish using loop-mediated isothermal amplification (LAMP)
It is now understood that the flatfish farming industry faces significant threats from Chinook salmon bafinivirus (CSBV) induced hemorrhagic disease. Developing a prompt and efficient diagnostic method is cruc...
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Article
Nanozymes for nanohealthcare
Nanozymes, nanomaterial-based artificial enzymes, exhibit potential for emulating the catalytic functions inherent in enzymes. Nanozymes have advantages such as low cost, facile synthesis, high stability and a...
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Open AccessControlled condensation by liquid contact-induced adaptations of molecular conformations in self-assembled monolayers
Surface condensation control strategies are crucial but commonly require relatively tedious, time-consuming, and expensive techniques for surface-chemical and topographical engineering. Here we report a strate...
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Open AccessBRAF/MEK-targeted therapy in BRAF ex15 p.T599dup mutation-driven NSCLC: a case report
BRAF mutations are found in 1–5% of non-small-cell lung cancer (NSCLC), with V600 and non-V600 accounting for approximately 50% each. It has been confirmed that targeted therapy with dabrafenib + trametinib is...
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Open AccessApurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer
APE1 is an essential gene involved in DNA damage repair, the redox regulation of transcriptional factors (TFs) and RNA processing. APE1 overexpression is common in cancers and correlates with poor patient surv...
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Article
Open AccessProteomic characterization identifies clinically relevant subgroups of soft tissue sarcoma
Soft tissue sarcoma is a broad family of mesenchymal malignancies exhibiting remarkable histological diversity. We portray the proteomic landscape of 272 soft tissue sarcomas representing 12 major subtypes. Hi...
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Inter-reflection compensation for immersive projection display
To ensure high-quality multi-projection display and fast projection scattering compensation processing, we propose a novel inter-reflection compensation algorithm for an immersive multi-projection system. Firs...
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Article
Graph Grammar Formalism with Multigranularity for Spatial Graphs
Traditional spatial enabled grammars lack flexibility in specifying the spatial semantics of graphs. This paper describes a new graph grammar formalism called the multigranularity Coordinate Graph Grammar (mgC...
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Article
GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis
Radioresistance is the primary reason for radiotherapy failure in non-small cell lung cancer (NSCLC) patients. Glycosylation-related alterations are critically involved in tumor radioresistance. However, the r...
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Article
The genetic evolution behavior of carbides in powder metallurgy FGH96 Ni-based superalloys
Understanding the evolution of carbides in FGH96 Ni-based superalloys during solidification carries profound significance in the context of regulating prior particle boundaries (PPBs) formation and enhancing t...
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Article
PKCι induces differential phosphorylation of STAT3 to modify STAT3-related signaling pathways in pancreatic cancer cells
An increasing number of studies have documented atypical protein kinase C isoform ι (PKCι) as an oncoprotein playing multifaceted roles in pancreatic carcinogenesis, including sustaining the transformed growth...
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Article
Microorganisms regulate soil phosphorus fractions in response to low nocturnal temperature by altering the abundance and composition of the pqqC gene rather than that of the phoD gene
Low nocturnal temperature (LNT) is a primary limitation in the greenhouse cultivation of vegetables during winter and spring, because it limits the availability of soil phosphorus (P), causing P-deficient symp...
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A CauchyTV non-convex regularization model for MRI reconstruction
In this paper, we study the non-convex regularization problem based on magnetic resonance imaging (MRI) reconstruction. In order to achieve high quality and fast reconstruction of MRI images, we use the non-co...
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Article
Open AccessKnowledge, attitude, and practice toward self-control of dental plaque among patients with periodontal diseases: a cross-sectional study
The development of periodontal disease is closely linked to individual oral healthcare behaviors. This study aimed to investigate the knowledge, attitude, and practice (KAP) toward the self-control of dental p...
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Open AccessAcaricidal and repellent activities of ethanol extracts of nine chinese medicinal herbs against Rhipicephalus microplus (Acari: Ixodidae)
Rhipicephalus microplus is a major threat to the cattle industry worldwide. The intensive use of acaricides and repellents has resulted in drug resistance. Hence, effective and eco-friendly pest control alternati...
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Open AccessOrbital-symmetry effects on magnetic exchange in open-shell nanographenes
Open-shell nanographenes appear as promising candidates for future applications in spintronics and quantum technologies. A critical aspect to realize this potential is to design and control the magnetic exchan...