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Open AccessGender differences in the association between healthy eating index-2015 and hypertension in the US population: evidence from NHANES 1999–2018
Diet has long been recognized as an important modifiable risk factor for hypertension. Herein, our research goal was to decipher the association of healthy eating index-2015 (HEI-2015) with hypertension, and t...
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Article
Open AccessAssociation between dietary inflammatory index and Stroke in the US population: evidence from NHANES 1999–2018
There is an increasing awareness that diet-related inflammation may have an impact on the stroke. Herein, our goal was to decipher the association of dietary inflammatory index (DII) with stroke in the US gene...
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Article
Open AccessA 2-decade bibliometric analysis of epigenetics of cardiovascular disease: from past to present
Cardiovascular disease (CVD) remains a major health killer worldwide, and the role of epigenetic regulation in CVD has been widely studied in recent decades. Herein, we perform a bibliometric study to decipher...
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Article
Association of Blood Heavy Metal Exposure with Atherosclerotic Cardiovascular Disease (ASCVD) Among White Adults: Evidence from NHANES 1999–2018
Cardiovascular diseases (CVD) are main public health concerns highly prevalent in industrialized societies where human health is threatened by a series of environmental pollutants, particularly heavy metal con...
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Article
Open AccessNuclear import of Mas-related G protein-coupled receptor member D induces pathological cardiac remodeling
Alamandine (Ala), a ligand of Mas-related G protein-coupled receptor, member D (MrgD), alleviates angiotensin II (AngII)-induced cardiac hypertrophy. However, the specific physiological and pathological role o...
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Article
The emerging role of leptin in obesity-associated cardiac fibrosis: evidence and mechanism
Cardiac fibrosis is a hallmark of various cardiovascular diseases, which is quite commonly found in obesity, and may contribute to the increased incidence of heart failure arrhythmias, and sudden cardiac death...
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Open AccessAlamandine alleviated heart failure and fibrosis in myocardial infarction mice
Alamandine (Ala) is the newest identified peptide of the renin-angiotensin system and has protective effect on myocyte hypertrophy. However, it is still unclear whether Ala can alleviate heart failure (HF). Th...
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Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts
The extent of myocardial fibrosis is closely related to the prognosis of diabetic cardiomyopathy (DCM). Low-intensity pulsed ultrasound (LIPUS) has been reported to have multiple biological effects. However, t...
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Open AccessOral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling
The vagus nerve can transmit signals to the brain resulting in a reduction in depressive behavior as evidenced by the long-term beneficial effects of electrical stimulation of the vagus in patients with intrac...