İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, 2022
In this study, the variability of the systemic immune inflammation index (SII), which is accepted... more In this study, the variability of the systemic immune inflammation index (SII), which is accepted as a new marker of inflammation, was investigated in patients with vitamin D deficiency. Biochemical and complete blood count data of outpatients were scanned and recorded retrospectively from digital data. SII was calculated for each patient based on whole blood parameters (neutrophil x platelet/lymphocyte). The relationship between SII and vitamin D variation was investigated. The mean age of the 113 patients included in the study was 38.58±12.37 years. Mean levels of vitamin D, B12 and folate were 13.68±6.57 ng/ml, 309.54±110.73 pg/ml and 7.13±2.77 ng/ml, respectively. The mean SII was 434.39±156.72. Vitamin D was below 10 ng/mL in 38 patients (33.6%). It was between 10-20 ng/mL in 56 patients (49.5%) and 20 ng/mL and above in 19 patients (16.8%). Vitamin B12 was significantly lower in the primary group than in the secondary group (p0.05). Vitamin D deficiency is one of the most comm...
Aim The aim of this study was to evaluate whether systemic immune-inflammation index (SII) could ... more Aim The aim of this study was to evaluate whether systemic immune-inflammation index (SII) could predict mortality in patients with novel coronavirus 2019 (COVID-19) disease. Methods This two-center, retrospective study included a total of 191 patients with confirmed diagnosis of COVID-19 via nucleic acid test (NAT). The SII was calculated based on the complete blood parameters (neutrophil × platelet/lymphocyte) during hospitalization. The relationship between the SII and other inflammatory markers and mortality was investigated. Results The mortality rate was 18.3%. The mean age was 54.32±17.95 years. The most common symptoms were fever (70.7%) and dry cough (61.3%), while 8 patients (4.2%) were asymptomatic. The most common comorbidities were hypertension (37.7%), diabetes (23.0%), chronic renal failure (14.7%), and heart failure (7.9%) which all significantly increased the mortality rate (p<0.001). There was a highly positive correlation between the SII and polymorphonuclear l...
Background. Metabolic syndrome (MetS) is associated with the risk of developing chronic kidney di... more Background. Metabolic syndrome (MetS) is associated with the risk of developing chronic kidney disease. Although the negative effects of high thyroid-stimulating hormone (TSH) values on glomerular filtration rate (GFR) levels have been known for years, the negative effects of increased TSH on GFR in euthyroid cases have been reported in recent years. This study was aimed at investigating the association between the effect of increased TSH values and estimated-GFR (eGFR) levels in euthyroid cases with MetS. Methods. For this hospital-based descriptive study, 191 MetS cases (123 females, 68 males) were evaluated. Those whose TSH was not within 0.5–4.5 uIU/mL, eGFR was <40 mL/min/1.73 m2, and/or reported any thyroid/kidney disease were excluded. Partial correlation coefficients were calculated to investigate the relationship between the eGFR values and several other numerical variables while controlling for age and BMI in addition to the adjusted gender effect. Thereafter, the multi...
İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, 2022
In this study, the variability of the systemic immune inflammation index (SII), which is accepted... more In this study, the variability of the systemic immune inflammation index (SII), which is accepted as a new marker of inflammation, was investigated in patients with vitamin D deficiency. Biochemical and complete blood count data of outpatients were scanned and recorded retrospectively from digital data. SII was calculated for each patient based on whole blood parameters (neutrophil x platelet/lymphocyte). The relationship between SII and vitamin D variation was investigated. The mean age of the 113 patients included in the study was 38.58±12.37 years. Mean levels of vitamin D, B12 and folate were 13.68±6.57 ng/ml, 309.54±110.73 pg/ml and 7.13±2.77 ng/ml, respectively. The mean SII was 434.39±156.72. Vitamin D was below 10 ng/mL in 38 patients (33.6%). It was between 10-20 ng/mL in 56 patients (49.5%) and 20 ng/mL and above in 19 patients (16.8%). Vitamin B12 was significantly lower in the primary group than in the secondary group (p0.05). Vitamin D deficiency is one of the most comm...
Aim The aim of this study was to evaluate whether systemic immune-inflammation index (SII) could ... more Aim The aim of this study was to evaluate whether systemic immune-inflammation index (SII) could predict mortality in patients with novel coronavirus 2019 (COVID-19) disease. Methods This two-center, retrospective study included a total of 191 patients with confirmed diagnosis of COVID-19 via nucleic acid test (NAT). The SII was calculated based on the complete blood parameters (neutrophil × platelet/lymphocyte) during hospitalization. The relationship between the SII and other inflammatory markers and mortality was investigated. Results The mortality rate was 18.3%. The mean age was 54.32±17.95 years. The most common symptoms were fever (70.7%) and dry cough (61.3%), while 8 patients (4.2%) were asymptomatic. The most common comorbidities were hypertension (37.7%), diabetes (23.0%), chronic renal failure (14.7%), and heart failure (7.9%) which all significantly increased the mortality rate (p<0.001). There was a highly positive correlation between the SII and polymorphonuclear l...
Background. Metabolic syndrome (MetS) is associated with the risk of developing chronic kidney di... more Background. Metabolic syndrome (MetS) is associated with the risk of developing chronic kidney disease. Although the negative effects of high thyroid-stimulating hormone (TSH) values on glomerular filtration rate (GFR) levels have been known for years, the negative effects of increased TSH on GFR in euthyroid cases have been reported in recent years. This study was aimed at investigating the association between the effect of increased TSH values and estimated-GFR (eGFR) levels in euthyroid cases with MetS. Methods. For this hospital-based descriptive study, 191 MetS cases (123 females, 68 males) were evaluated. Those whose TSH was not within 0.5–4.5 uIU/mL, eGFR was <40 mL/min/1.73 m2, and/or reported any thyroid/kidney disease were excluded. Partial correlation coefficients were calculated to investigate the relationship between the eGFR values and several other numerical variables while controlling for age and BMI in addition to the adjusted gender effect. Thereafter, the multi...
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Papers by Tahsin Karaaslan