Women were not allowed to graduate from Cambridge University before 1948. It wasn't until 1969, w... more Women were not allowed to graduate from Cambridge University before 1948. It wasn't until 1969, when Princeton University admitted women.
It has been suggested that computer-assisted instruction (CAI) is a promising method for educatin... more It has been suggested that computer-assisted instruction (CAI) is a promising method for educating students on the autism spectrum. We aimed to determine whether automated recognition of facial expressions aided in predicting CAI engagement and learning performance. Seven youth with autism (mean age = 12.7, SD = 4.2) interacted with a CAI program, TeachTown Basics, for 15 consecutive sessions. Video recordings of the participants' faces were collected during these sessions and facial expressions from these videos were analyzed using CERT, an algorithm that automatically outputs intensity values for each facial action unit (AU). Using these data, we attempted to operationally define two engagement indices:
Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecogniti... more Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecognition of clinical pain. Facial expressions are a sensitive, specific biomarker of the presence and severity of pain, and computer vision (CV) and machine-learning (ML) techniques enable reliable, valid measurement of pain-related facial expressions from video. We developed and evaluated a CVML approach to measure pain-related facial expressions for automated pain assessment in youth. A CVML-based model for assessment of pediatric postoperative pain was developed from videos of 50 neurotypical youth 5 to 18 years old in both endogenous/ongoing and exogenous/transient pain conditions after laparoscopic appendectomy. Model accuracy was assessed for self-reported pain ratings in children and time since surgery, and compared with by-proxy parent and nurse estimates of observed pain in youth. Model detection of pain versus no-pain demonstrated good-to-excellent accuracy (Area under the receiver o...
Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecogniti... more Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecognition of clinical pain. Facial expressions are a sensitive, specific biomarker of the presence and severity of pain, and computer vision (CV) and machine-learning (ML) techniques enable reliable, valid measurement of pain-related facial expressions from video. We developed and evaluated a CVML approach to measure pain-related facial expressions for automated pain assessment in youth. A CVML-based model for assessment of pediatric postoperative pain was developed from videos of 50 neurotypical youth 5 to 18 years old in both endogenous/ongoing and exogenous/transient pain conditions after laparoscopic appendectomy. Model accuracy was assessed for self-reported pain ratings in children and time since surgery, and compared with by-proxy parent and nurse estimates of observed pain in youth. Model detection of pain versus no-pain demonstrated good-to-excellent accuracy (Area under the receiver o...
Despite often showing behaviorally typical levels of social cognitive ability, unaffected sibling... more Despite often showing behaviorally typical levels of social cognitive ability, unaffected siblings of children with autism spectrum disorder have been found to show similar functional and morphological deficits within brain regions associated with social processing. They have also been reported to show increased activation to biological motion in these same regions, such as the posterior superior temporal sulcus (pSTS), relative to both children with autism and control children. It has been suggested that this increased activation may represent a compensatory reorganization of these regions as a result of the highly heritable genetic influence of autism. However, the response patterns of unaffected siblings in the domain of action perception are unstudied, and the phenomenon of compensatory activation has not yet been replicated. The present study used functional magnetic resonance imaging to determine the neural responses to intentional biological actions in 22 siblings of children with autism and 22 matched controls. The presented actions were either congruent or incongruent with the actor's emotional cue. Prior studies reported that typically developing children and adults, but not children with autism, show increased activation to incongruent actions (relative to congruent), within the pSTS and dorsolateral prefrontal cortex. We report that unaffected siblings did not show a compensatory response, or a preference for incongruent over congruent trials, in any brain region. Moreover, interaction analyses revealed a sub-region of the pSTS in which control children showed an incongruency preference to a significantly greater degree than siblings, which suggests a localized deficit in siblings. A sample of children with autism also did not show differential activation in the pSTS, providing further evidence that it is an area of selective disruption in children with autism and siblings. While reduced activation to both conditions was unique to the autism sample, lack of differentiation to incongruent and congruent intentional actions was common to both children with ASD and unaffected siblings.
Women were not allowed to graduate from Cambridge University before 1948. It wasn't until 1969, w... more Women were not allowed to graduate from Cambridge University before 1948. It wasn't until 1969, when Princeton University admitted women.
It has been suggested that computer-assisted instruction (CAI) is a promising method for educatin... more It has been suggested that computer-assisted instruction (CAI) is a promising method for educating students on the autism spectrum. We aimed to determine whether automated recognition of facial expressions aided in predicting CAI engagement and learning performance. Seven youth with autism (mean age = 12.7, SD = 4.2) interacted with a CAI program, TeachTown Basics, for 15 consecutive sessions. Video recordings of the participants' faces were collected during these sessions and facial expressions from these videos were analyzed using CERT, an algorithm that automatically outputs intensity values for each facial action unit (AU). Using these data, we attempted to operationally define two engagement indices:
Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecogniti... more Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecognition of clinical pain. Facial expressions are a sensitive, specific biomarker of the presence and severity of pain, and computer vision (CV) and machine-learning (ML) techniques enable reliable, valid measurement of pain-related facial expressions from video. We developed and evaluated a CVML approach to measure pain-related facial expressions for automated pain assessment in youth. A CVML-based model for assessment of pediatric postoperative pain was developed from videos of 50 neurotypical youth 5 to 18 years old in both endogenous/ongoing and exogenous/transient pain conditions after laparoscopic appendectomy. Model accuracy was assessed for self-reported pain ratings in children and time since surgery, and compared with by-proxy parent and nurse estimates of observed pain in youth. Model detection of pain versus no-pain demonstrated good-to-excellent accuracy (Area under the receiver o...
Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecogniti... more Current pain assessment methods in youth are suboptimal and vulnerable to bias and underrecognition of clinical pain. Facial expressions are a sensitive, specific biomarker of the presence and severity of pain, and computer vision (CV) and machine-learning (ML) techniques enable reliable, valid measurement of pain-related facial expressions from video. We developed and evaluated a CVML approach to measure pain-related facial expressions for automated pain assessment in youth. A CVML-based model for assessment of pediatric postoperative pain was developed from videos of 50 neurotypical youth 5 to 18 years old in both endogenous/ongoing and exogenous/transient pain conditions after laparoscopic appendectomy. Model accuracy was assessed for self-reported pain ratings in children and time since surgery, and compared with by-proxy parent and nurse estimates of observed pain in youth. Model detection of pain versus no-pain demonstrated good-to-excellent accuracy (Area under the receiver o...
Despite often showing behaviorally typical levels of social cognitive ability, unaffected sibling... more Despite often showing behaviorally typical levels of social cognitive ability, unaffected siblings of children with autism spectrum disorder have been found to show similar functional and morphological deficits within brain regions associated with social processing. They have also been reported to show increased activation to biological motion in these same regions, such as the posterior superior temporal sulcus (pSTS), relative to both children with autism and control children. It has been suggested that this increased activation may represent a compensatory reorganization of these regions as a result of the highly heritable genetic influence of autism. However, the response patterns of unaffected siblings in the domain of action perception are unstudied, and the phenomenon of compensatory activation has not yet been replicated. The present study used functional magnetic resonance imaging to determine the neural responses to intentional biological actions in 22 siblings of children with autism and 22 matched controls. The presented actions were either congruent or incongruent with the actor's emotional cue. Prior studies reported that typically developing children and adults, but not children with autism, show increased activation to incongruent actions (relative to congruent), within the pSTS and dorsolateral prefrontal cortex. We report that unaffected siblings did not show a compensatory response, or a preference for incongruent over congruent trials, in any brain region. Moreover, interaction analyses revealed a sub-region of the pSTS in which control children showed an incongruency preference to a significantly greater degree than siblings, which suggests a localized deficit in siblings. A sample of children with autism also did not show differential activation in the pSTS, providing further evidence that it is an area of selective disruption in children with autism and siblings. While reduced activation to both conditions was unique to the autism sample, lack of differentiation to incongruent and congruent intentional actions was common to both children with ASD and unaffected siblings.
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Papers by Alex Ahmed