To compare pregnancy rates with two different methods of intrauterine insemination (IUI) timing i... more To compare pregnancy rates with two different methods of intrauterine insemination (IUI) timing in patients treated with clomiphene citrate (CC). Prospective, randomized trial. Academic medical center. One hundred fifty ovulatory, infertile women. Patients were randomized into a luteinizing hormone (LH) surge group or a follicle monitoring/human chorionic gonadotropin (hCG) group. All patients underwent baseline ultrasound, and took clomiphene citrate, during days 5-9. Patients in the LH surge group underwent IUI on the day after a home test for the LH surge was positive, whereas those in the hCG group received hCG according to ultrasound parameters and underwent insemination 33-40 hours later. Patients remained in the same study group for up to three cycles. Pregnancy rates per cycle and per patient. No significant differences were found between groups in pregnancy rates per patient or per cycle. The LH surge group underwent IUI significantly later than the hCG group. Cancellation ...
American journal of obstetrics and gynecology, Jan 15, 1984
The increase in uterine blood flow during pregnancy is maximal at the placental implantation site... more The increase in uterine blood flow during pregnancy is maximal at the placental implantation site, but the mechanisms of this increase are poorly understood. Adrenergic receptor activation may influence blood flow both directly and indirectly. We therefore asked whether distribution of myometrial adrenergic receptors within the rabbit uterus could explain the increased blood flow to smooth muscle under the placenta. alpha-Adrenergic and beta-adrenergic receptor concentrations and affinities were measured in myometrium from under the placenta and compared to myometrium between placentas and distant from the placentas. There were no differences in receptor concentrations or affinities in different parts of the uterus. We therefore conclude that the distribution of adrenergic receptors in the pregnant rabbit uterus cannot explain the preferential blood flow to myometrium at the placental implantation site.
In this report, we describe a six-year experience (2007-2012) in a single CTSA awardee institutio... more In this report, we describe a six-year experience (2007-2012) in a single CTSA awardee institution on the development, implementation and evaluation of a hybrid online mentoring curriculum that is applicable to CTSA trainees at various levels (graduate, medical students, and junior faculty) of career training. The curriculum offers convenience, engagement, and financial sustainability. Overall, we found high levels of satisfaction with the curriculum and mentoring experience among both protégés and mentors. Qualitative data showed remarkable consensus of 14 of the 15 domains of mentoring that form the framework of the mentoring curriculum: (1) accessibility, (2) selectivity, (3) engagement/support, (4) teaching/training, (5) clarity of performance/expectations, (6) sponsorship/sharing power judiciously, (7) demystifying the system (academia), (8) challenging/encouraging risk taking, (9) affirming, (10) providing exposure/visibility, (11) being an intentional role model, (12) protect...
To compare pregnancy rates with two different methods of intrauterine insemination (IUI) timing i... more To compare pregnancy rates with two different methods of intrauterine insemination (IUI) timing in patients treated with clomiphene citrate (CC). Prospective, randomized trial. Academic medical center. One hundred fifty ovulatory, infertile women. Patients were randomized into a luteinizing hormone (LH) surge group or a follicle monitoring/human chorionic gonadotropin (hCG) group. All patients underwent baseline ultrasound, and took clomiphene citrate, during days 5-9. Patients in the LH surge group underwent IUI on the day after a home test for the LH surge was positive, whereas those in the hCG group received hCG according to ultrasound parameters and underwent insemination 33-40 hours later. Patients remained in the same study group for up to three cycles. Pregnancy rates per cycle and per patient. No significant differences were found between groups in pregnancy rates per patient or per cycle. The LH surge group underwent IUI significantly later than the hCG group. Cancellation ...
American journal of obstetrics and gynecology, Jan 15, 1984
The increase in uterine blood flow during pregnancy is maximal at the placental implantation site... more The increase in uterine blood flow during pregnancy is maximal at the placental implantation site, but the mechanisms of this increase are poorly understood. Adrenergic receptor activation may influence blood flow both directly and indirectly. We therefore asked whether distribution of myometrial adrenergic receptors within the rabbit uterus could explain the increased blood flow to smooth muscle under the placenta. alpha-Adrenergic and beta-adrenergic receptor concentrations and affinities were measured in myometrium from under the placenta and compared to myometrium between placentas and distant from the placentas. There were no differences in receptor concentrations or affinities in different parts of the uterus. We therefore conclude that the distribution of adrenergic receptors in the pregnant rabbit uterus cannot explain the preferential blood flow to myometrium at the placental implantation site.
In this report, we describe a six-year experience (2007-2012) in a single CTSA awardee institutio... more In this report, we describe a six-year experience (2007-2012) in a single CTSA awardee institution on the development, implementation and evaluation of a hybrid online mentoring curriculum that is applicable to CTSA trainees at various levels (graduate, medical students, and junior faculty) of career training. The curriculum offers convenience, engagement, and financial sustainability. Overall, we found high levels of satisfaction with the curriculum and mentoring experience among both protégés and mentors. Qualitative data showed remarkable consensus of 14 of the 15 domains of mentoring that form the framework of the mentoring curriculum: (1) accessibility, (2) selectivity, (3) engagement/support, (4) teaching/training, (5) clarity of performance/expectations, (6) sponsorship/sharing power judiciously, (7) demystifying the system (academia), (8) challenging/encouraging risk taking, (9) affirming, (10) providing exposure/visibility, (11) being an intentional role model, (12) protect...
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