User profiles for xiaofeng huang weill

Xiaofeng (Steve) Huang

Assistant Professor, Weill Cornell Medical College
Verified email at med.cornell.edu
Cited by 571

Stomach-derived human insulin-secreting organoids restore glucose homeostasis

X Huang, W Gu, J Zhang, Y Lan, JL Colarusso, S Li… - Nature cell …, 2023 - nature.com
… Samples were kept in GINS medium on ice until ready to be processed by 10x Genomics
single-cell droplet sample preparation workflow at the Genomics Core Facility at Weill Cornell …

[HTML][HTML] SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

W Gu, H Wang, X Huang, J Kraiczy, PNP Singh, C Ng… - Cell Stem Cell, 2022 - cell.com
Adult stem cells maintain regenerative tissue structure and function by producing tissue-specific
progeny, but the factors that preserve their tissue identities are not well understood. The …

Generation of DelNS1 influenza viruses: a strategy for optimizing live attenuated influenza vaccines

…, SY Lau, P Chen, BWY Mok, S Liu, H Liu, X Huang… - MBio, 2019 - Am Soc Microbiol
Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional
roles in virus replication and a potent antagonist of host immune response. Deletion of …

A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin

W Gu, X Huang, PNP Singh, S Li, Y Lan… - Nature …, 2024 - nature.com
Plasticity among cell lineages is a fundamental, but poorly understood, property of regenerative
tissues. In the gut tube, the small intestine absorbs nutrients, whereas the colon absorbs …

Restoring glucose homeostasis with stomach-derived human insulin-secreting organoids

X Huang, W Gu, J Zhang, Y Lan, JL Colarusso, S Li… - BioRxiv, 2022 - biorxiv.org
… All studies involving human samples were approved by the ethical committee at Weill Cornell
Medical College. Human stomach samples were obtained from Children’s Hospital Boston…

[PDF][PDF] Generation of gastirc insulin-secreting organoids from human stomach sample.

X Huang, Q Zhou - Research Square, 2023 - pdfs.semanticscholar.org
Stomach stem cells are accessible by biopsy and propagate robustly in culture, offering an
invaluable resource for autologous cell therapies. Here we describe a detailed protocol to …

[PDF][PDF] Current Research in Biotechnology

CJ Cremin, S Dash, X Huang - researchgate.net
Big data is transforming biomedical research by integrating massive amounts of data from
laboratory experiments, clinical investigations, healthcare records, and the internet of things. …

DrugComboRanker: drug combination discovery based on target network analysis

L Huang, F Li, J Sheng, X Xia, J Ma, M Zhan… - …, 2014 - academic.oup.com
Motivation: Currently there are no curative anticancer drugs, and drug resistance is often
acquired after drug treatment. One of the reasons is that cancers are complex diseases, …

Percutaneous vertebroplasty versus conservative treatment in aged patients with acute osteoporotic vertebral compression fractures: a prospective randomized …

EZ Yang, JG Xu, GZ Huang, WZ Xiao, XK Liu, BF Zeng… - 2016 - journals.lww.com
… Address correspondence and reprint requests to Xiao-Feng Lian, MD, PhD, Department
of … The authors thank Thamina Khair from Brain and Spine Center of Weill Cornell Medical …

PUMA and BIM are required for oncogene inactivation–induced apoptosis

…, Y Dong, S Takeda, H Liu, PM Chan, Y Huang… - Science …, 2013 - science.org
The clinical efficacy of tyrosine kinase inhibitors supports the dependence of distinct
subsets of cancers on specific driver mutations for survival, a phenomenon called “oncogene …