DCPG

DCPG
(IUPAC) ime
	4-[(1S)-1-amino-2-hidroksi-2-oksoetil]ftalna kiselina
Klinički podaci
Identifikatori
CAS broj	201730-11-2
ATC kod	nije dodeljen
PubChem	16062593
Hemijski podaci
Formula	C10H9NO6
Mol. masa	239,181 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1 ; Key: IJVMOGKBEVRBPP-ZETCQYMHSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

DCPG ((S)-3,4-DCPG) je lek koji se koristi u naučnim istraživanjima. On deluje kao potentan i selektivan agonist za metabotropni glutamatni receptor mGluR₈. On ima antikonvulzivno dejstvo u životinjskim studijama.^[3]^[4] On je takođe istraživan kao mogući tretman za hiperalgeziju.^[5]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Moldrich RX, Chapman AG, De Sarro G, Meldrum BS. Glutamate metabotropic receptors as targets for drug therapy in epilepsy. European Journal of Pharmacology. 2003 Aug 22;476(1-2):3-16. DOI:10.1016/S0014-2999(03)02149-6 PMID 12969743
↑ Folbergrová J, Druga R, Haugvicová R, Mares P, Otáhal J. Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid. Neuropharmacology. 2008 Mar;54(4):665-75. PMID 18191956
↑ Marabese I, de Novellis V, Palazzo E, Scafuro MA, Vita D, Rossi F, Maione S. Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice. Neuropharmacology. 2007 Feb;52(2):253-62. PMID 17113112

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