HDEP-28

HDEP-28
Pravni status
Pravni status	CA: Seznam III ; DE: NpSG ; UK: Class B ;
Identifikatorji
	IUPAC ime Etil (naftalen-2-il)(piperidin-2-il)acetat;
Številka CAS	2170529-69-6;
PubChem CID	91844468;
ChemSpider	52085106;
UNII	A8326SH248;
CompTox Dashboard (EPA)	DTXSID601336139 ;
Kemični in fizikalni podatki
Formula	C19H23NO2
Mol. masa	297,40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOC(=O)C(C1CCCCN1)c2ccc3ccccc3c2;
	InChI InChI=1S/C19H23NO2/c1-2-22-19(21)18(17-9-5-6-12-20-17)16-11-10-14-7-3-4-8-15(14)13-16/h3-4,7-8,10-11,13,17-18,20H,2,5-6,9,12H2,1H3; Key:OTQVTBPHZRARTL-UHFFFAOYSA-N;

HDEP-28 ali etilnaftidat je stimulativna droga na osnovi piperidina, strukturno zelo sorodna etilfenidatu, vendar z zamenjavo benzenskega obroča z naftalenskim. Strukturno še sorodnejši je HDMP-28, ki deluje kot kratkodelujoč močan zaviralec ponovnega privzema serotonina-noradrenalina-dopamina z nekajkrat večjo jakostjo delovanja od metilfenidata.^[1]

Pravni status

HDEP-28 je v Združenem kraljestvu prepovedan od junija 2015 po neodobreni prodaji kot dizajnerske droge skupaj s 4-metilmetilfenidatom.^[2]^[3]^[4]

Sklici

↑ Lile JA, Wang Z, Woolverton WL, France JE, Gregg TC, Davies HM, Nader MA (Oktober 2003). »The reinforcing efficacy of psychostimulants in rhesus monkeys: the role of pharmacokinetics and pharmacodynamics«. The Journal of Pharmacology and Experimental Therapeutics. 307 (1): 356–66. doi:10.1124/jpet.103.049825. PMID 12954808.
↑ Methylphenidate-based NPS: A review of the evidence of use and harm. Advisory Council on the Misuse of Drugs, 31. 3. 2015
↑ »Letter to Mike Penning on methylphenidate-based novel psychoactive substances«. Advisory Council on the Misuse of Drugs. 25. junij 2015. Pridobljeno 25. junija 2015.
↑ »Ministerial response to the Advisory Council on the Misuse of Drugs about 2 new methylphenidate-based substances«. Home Office. 25. junij 2015. Pridobljeno 25. junija 2015.

[pmid12954808-1] Lile JA, Wang Z, Woolverton WL, France JE, Gregg TC, Davies HM, Nader MA (Oktober 2003). »The reinforcing efficacy of psychostimulants in rhesus monkeys: the role of pharmacokinetics and pharmacodynamics«. The Journal of Pharmacology and Experimental Therapeutics. 307 (1): 356–66. doi:10.1124/jpet.103.049825. PMID 12954808.

[2] Methylphenidate-based NPS: A review of the evidence of use and harm. Advisory Council on the Misuse of Drugs, 31. 3. 2015

[3] »Letter to Mike Penning on methylphenidate-based novel psychoactive substances«. Advisory Council on the Misuse of Drugs. 25. junij 2015. Pridobljeno 25. junija 2015.

[4] »Ministerial response to the Advisory Council on the Misuse of Drugs about 2 new methylphenidate-based substances«. Home Office. 25. junij 2015. Pridobljeno 25. junija 2015.

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