Serological evidences of CMV and Chlamydia pneumoniae infectious were highly prevalent in all human population samples. There was a limited epidemiological data relating these infections to myocardial ischemic disease (IHD) and future... more
Serological evidences of CMV and Chlamydia pneumoniae infectious were highly prevalent in all human population samples. There was a limited epidemiological data relating these infections to myocardial ischemic disease (IHD) and future risks in patients with acute coronary syndrome (ACS) and atherosclerosis. The aim of our study were to evaluated: (i) the serum levels of IgG antibodies to CMV and Chlamydia pneumoniae in patients with different CVDs and healthy controls; and (ii) the risks related to persistent CMV and chronic C. pneumoniae infections for late cardiac events in the general population. Plasma specimens were collected from 93 patients (55 men and 38 women aged 41-85) who have been hospitalized in IV th Cardiology Clinic affiliated to Medical University-Sofia. They were analysed for IgG antibodies to CMV and C. pneumoniae by ELISA. The patients were divided into 4 groups: 1) chronically IHD; 2) ACS; 3) stable angina pectoris (AP); and 4) healthy controls. 52 cases (94,5 ...